Standout Papers

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub>... 1998 2026 2007 2016 4.5k
  1. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation (2001)
    Panu Jaakkola, David R. Mole et al. Science
  2. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis (1999)
    Patrick H. Maxwell, Michael S. Wiesener et al. Nature
  3. C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation (2001)
    Andrew Epstein, Jonathan Gleadle et al. Cell
  4. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (1998)
    Peter Carmeliet, Yuval Dor et al. Nature
  5. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. (2000)
    Charles C. Wykoff, Nigel Beasley et al. PubMed
  6. The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages (2000)
    Helen Turley, Kevin C. Gatter et al. American Journal Of Pathology
  7. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth (1997)
    Patrick H. Maxwell, Gabi U. Dachs et al. Proceedings of the National Academy of Sciences
  8. Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein (2000)
    Matthew E. Cockman, Norma Masson et al. Journal of Biological Chemistry
  9. Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation (2001)
    Norma Masson, Carsten Willam et al. The EMBO Journal
  10. Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma (2005)
    Raju R. Raval, Maxine Tran et al. Molecular and Cellular Biology
  11. Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL (2002)
    Wai‐Ching Hon, Michael Wilson et al. Nature
  12. Widespread, hypoxia‐inducible expression of HIF‐2α in distinct cell populations of different organs (2002)
    Michael S. Wiesener, Jan Steffen Jürgensen et al. The FASEB Journal
  13. Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α (1998)
    Michael S. Wiesener, Helen Turley et al. Blood
  14. Expression of Hypoxia-Inducible Factor-1α and -2α in Hypoxic and Ischemic Rat Kidneys (2002)
    Christian Rosenberger, Stefano J. Mandriota et al. Journal of the American Society of Nephrology
  15. HIF activation identifies early lesions in VHL kidneys (2002)
    Stefano J. Mandriota, Kevin Turner et al. Cancer Cell
  16. Identification of the renal erythropoietin-producing cells using transgenic mice (1993)
    Patrick H. Maxwell, Mark Osmond et al. Kidney International

Immediate Impact

223 by Nobel laureates 50 from Science/Nature 337 standout
Sub-graph 1 of 12

Citing Papers

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9 intermediate papers

Works of Patrick H. Maxwell being referenced

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
and 11 more

Author Peers

Author Last Decade Papers Cites
Patrick H. Maxwell 21346 19893 5156 208 34.1k
Christopher W. Pugh 21532 19067 5142 142 32.0k
M. Celeste Simon 20715 25915 4122 259 46.7k
Jacques Pouysségur 12099 28749 2687 368 41.5k
Chi V. Dang 23758 38321 2975 299 52.1k
William G. Kaelin 22252 35237 5899 244 49.6k
Bing‐Hua Jiang 15985 19202 2972 306 31.1k
Matthew G. Vander Heiden 25534 36431 1848 218 53.1k
Amato J. Giaccia 17174 22859 2567 346 39.7k
Werner Risau 9220 26986 1725 148 37.9k
Eamonn R. Maher 11620 19136 7556 415 31.7k

All Works

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