Standout Papers

The Inflammasome 2002 2026 2010 2018 4.8k
  1. The Inflammasome (2002)
    Fabio Martinon, Kimberly Burns et al. Molecular Cell
  2. The Inflammasomes (2010)
    Kate Schroder, Jürg Tschopp Cell
  3. A role for mitochondria in NLRP3 inflammasome activation (2010)
    Rongbin Zhou, Amir S. Yazdi et al. Nature
  4. Gout-associated uric acid crystals activate the NALP3 inflammasome (2006)
    Fabio Martinon, Virginie Pétrilli et al. Nature
  5. Thioredoxin-interacting protein links oxidative stress to inflammasome activation (2009)
    Rongbin Zhou, Aubry Tardivel et al. Nature Immunology
  6. Inhibition of death receptor signals by cellular FLIP (1997)
    Martin Irmler, Margot Thome et al. Nature
  7. Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica (2008)
    Catherine Dostert, Virginie Pétrilli et al. Science
  8. Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes (2003)
    Olivier Micheau, Jürg Tschopp Cell
  9. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus (2005)
    Etienne Meylan, Joseph Curran et al. Nature
  10. The Inflammasomes: Guardians of the Body (2009)
    Fabio Martinon, Jürg Tschopp et al. Annual Review of Immunology
  11. Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule (2000)
    Nils Holler, Rossana Zaru et al. Nature Immunology
  12. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? (2010)
    Jürg Tschopp, Kate Schroder Nature reviews. Immunology
  13. NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder (2004)
    Laetitia Agostini, Fabio Martinon et al. Immunity
  14. Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations (1999)
    Fabienne Mackay, Christine Ambrose et al. The Journal of Experimental Medicine
  15. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration (2007)
    Virginie Pétrilli, Stéphanie Papin et al. Cell Death and Differentiation
  16. BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth (1999)
    Pascal Schneider, Fabienne Mackay et al. The Journal of Experimental Medicine
  17. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors (1997)
    Margot Thome, Pascal Schneider et al. Nature
  18. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways (1994)
    Bente Lowin, Michael Hahne et al. Nature
  19. Intracellular pattern recognition receptors in the host response (2006)
    Etienne Meylan, Jürg Tschopp et al. Nature
  20. The NLRP3 Inflammasome: A Sensor for Metabolic Danger? (2010)
    Kate Schroder, Rongbin Zhou et al. Science
  21. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response (2008)
    Daniel A. Muruve, Virginie Pétrilli et al. Nature
  22. BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF (2001)
    Jeffrey S. Thompson, Sarah A. Bixler et al. Science
  23. Inflammatory Caspases (2004)
    Fabio Martinon, Jürg Tschopp Cell
  24. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence (2009)
    Olaf Groß, Hendrik Poeck et al. Nature
  25. Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation (2011)
    Greta Guarda, Marion Braun et al. Immunity
  26. The molecular architecture of the TNF superfamily (2002)
    Jean-Luc Bodmer, Pascal Schneider et al. Trends in Biochemical Sciences
  27. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome (2002)
    Joanna R. Groom, Susan L. Kalled et al. Journal of Clinical Investigation
  28. RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation (2004)
    Etienne Meylan, Kim Burns et al. Nature Immunology
  29. Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation (2011)
    James Harris, Michelle Hartman et al. Journal of Biological Chemistry
  30. The inflammasome: an integrated view (2011)
    Olaf Groß, Christina J. Thomas et al. Immunological Reviews
  31. Inflammatory caspases and inflammasomes: master switches of inflammation (2006)
    Fabio Martinon, Jürg Tschopp Cell Death and Differentiation
  32. TRAIL Receptors 1 (DR4) and 2 (DR5) Signal FADD-Dependent Apoptosis and Activate NF-κB (1997)
    Pascal Schneider, Margot Thome et al. Immunity
  33. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome (2002)
    Joanna R. Groom, Susan L. Kalled et al. Journal of Clinical Investigation
  34. Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation (2013)
    Yiqing Yan, Wei Jiang et al. Immunity
  35. Baff Mediates Survival of Peripheral Immature B Lymphocytes (2000)
    Marcel Batten, Joanna R. Groom et al. The Journal of Experimental Medicine
  36. NALPs: a novel protein family involved in inflammation (2003)
    Jürg Tschopp, Fabio Martinon et al. Nature Reviews Molecular Cell Biology
  37. The inflammasome: a danger sensing complex triggering innate immunity (2007)
    Virginie Pétrilli, Catherine Dostert et al. Current Opinion in Immunology
  38. A pilot study of IL-1 inhibition by anakinra in acute gout (2007)
    Alexander So, Thibaut De Smedt et al. Arthritis Research & Therapy
  39. MyD88, an Adapter Protein Involved in Interleukin-1 Signaling (1998)
    Kimberly Burns, Fabio Martinon et al. Journal of Biological Chemistry

Immediate Impact

5 by Nobel laureates 89 from Science/Nature 233 standout
Sub-graph 1 of 11

Citing Papers

The microbiome and innate immunity
2016 StandoutNature
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
2016 StandoutNature
42 intermediate papers

Works of Jürg Tschopp being referenced

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
2007 Standout
The Inflammasome
2002 Standout
and 52 more

Author Peers

Author Last Decade Papers Cites
Jürg Tschopp 42911 51322 7960 11729 282 86.1k
Katherine A. Fitzgerald 39041 37056 6753 12136 331 67.9k
Gabriel Núñez 33855 47173 6432 10577 407 83.1k
Charles A. Dinarello 46442 36261 5474 15647 864 106.0k
Vishva M. Dixit 32645 61633 15634 9085 312 86.9k
Eicke Latz 31007 31605 3603 8780 278 59.6k
Russell Ross 17410 24997 8951 9760 241 78.4k
Anthony Cerami 20595 18668 3529 10646 513 75.8k
Kiyoshi Takeda 56555 27378 10436 14493 454 91.3k
Ruslan Medzhitov 60569 27356 8820 13228 221 95.1k
Shigekazu Nagata 32653 41993 6606 7736 608 75.6k

All Works

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2026