Standout Papers

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expr... 1998 2026 2007 2016 1.3k
  1. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. (1998)
    J�rgen Lehmann, David D. McKee et al. Journal of Clinical Investigation
  2. An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway (1998)
    Steven A. Kliewer, John T. Moore et al. Cell
  3. Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition (2002)
    Randy K. Bledsoe, Valerie G. Montana et al. Cell
  4. Nuclear Pregnane X Receptor and Constitutive Androstane Receptor Regulate Overlapping but Distinct Sets of Genes Involved in Xenobiotic Detoxification (2002)
    Jodi M. Maglich, Bryan Goodwin et al. Molecular Pharmacology
  5. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα (2002)
    H. Eric Xu, Thomas B. Stanley et al. Nature

Immediate Impact

12 by Nobel laureates 55 from Science/Nature 182 standout
Sub-graph 1 of 14

Citing Papers

Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Nuclear Receptors, RXR, and the Big Bang
2014 Standout
51 intermediate papers

Works of John T. Moore being referenced

The Nuclear Receptor Superfamily and Drug Discovery
2006
An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway
1998 Standout
and 11 more

Author Peers

Author Last Decade Papers Cites
John T. Moore 3485 3149 938 3393 68 9.0k
David D. McKee 3516 2656 1447 2808 23 8.7k
Tatsuya Sueyoshi 2362 1676 479 3725 87 6.6k
Bryan Goodwin 4534 2459 3487 4891 69 13.9k
Derek J. Parks 4289 1784 2225 1333 39 9.3k
Charles N. Falany 3311 1531 758 2670 147 7.0k
G. Bruce Wisely 5826 1976 1417 1548 37 10.0k
Linda B. Moore 7064 2826 3015 3304 44 13.6k
Jon L. Collins 4986 1497 3499 2044 69 10.3k
Dean W. Hum 2763 1058 917 1785 91 5.8k
Philip S. Guzelian 2369 1120 895 5897 119 9.8k

All Works

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2026