Giuseppe Legname

Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

In vitro aggregation assays for the characterization of α-synuclein prion-like properties

Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes