Standout Papers

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidatio... 1993 2026 2004 2015 2.3k
  1. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. (1994)
    Tsutomu Shimada, Hiroshi Yamazaki et al. Journal of Pharmacology and Experimental Therapeutics
  2. The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature (1993)
    David R. Nelson, T. Kamataki et al. DNA and Cell Biology
  3. Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity (2001)
    F. Peter Guengerich Chemical Research in Toxicology
  4. Cytochrome P450 and Chemical Toxicology (2007)
    F. Peter Guengerich Chemical Research in Toxicology
  5. CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism (1999)
    F. Peter Guengerich The Annual Review of Pharmacology and Toxicology
  6. Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone (1982)
    F. Peter Guengerich, Ghazi A. Dannan et al. Biochemistry
  7. The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature (1991)
    Daniel W. Nebert, David R. Nelson et al. DNA and Cell Biology
  8. Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes (1991)
    F. Peter Guengerich, Tsutomu Shimada Chemical Research in Toxicology
  9. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. (1986)
    F. Peter Guengerich, M V Martin et al. Journal of Biological Chemistry
  10. The P450 Gene Superfamily: Recommended Nomenclature (1987)
    Daniel W. Nebert, Milton Adesnik et al. DNA
  11. Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat (1985)
    Ronald A. Lubet, Richard T. Mayer et al. Archives of Biochemistry and Biophysics
  12. Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. (1989)
    Marguerite A. Butler, M. Iwasaki et al. Proceedings of the National Academy of Sciences
  13. Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes (1985)
    David J. Waxman, Ghazi A. Dannan et al. Biochemistry
  14. The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci (1989)
    Daniel W. Nebert, David R. Nelson et al. DNA
  15. Reactions and significance of cytochrome P-450 enzymes (1991)
    F. Peter Guengerich Journal of Biological Chemistry
  16. Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis (1982)
    F. Peter Guengerich, Philip Wang et al. Biochemistry
  17. Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals (2014)
    Slobodan Rendić, F. Peter Guengerich Chemical Research in Toxicology
  18. Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis (2017)
    Tatiana Y. Hargrove, Laura Friggeri et al. Journal of Biological Chemistry

Immediate Impact

18 by Nobel laureates 26 from Science/Nature 84 standout
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Works of F. Peter Guengerich being referenced

Mechanisms of Cytochrome P450-Catalyzed Oxidations
2018
Complex reactions catalyzed by cytochrome P450 enzymes
2006
and 28 more

Author Peers

Author Last Decade Papers Cites
F. Peter Guengerich 37244 26888 16701 936 67.4k
Frank J. Gonzalez 30954 55848 26726 1.3k 117.1k
Daniel W. Nebert 16623 18406 8295 488 45.2k
Timothy M. Willson 7208 30944 13832 225 53.2k
Magnus Ingelman‐Sundberg 17831 10603 7725 523 34.7k
Bharat B. Aggarwal 6771 47593 13641 558 101.1k
David J. Waxman 12260 11711 9387 371 30.9k
Masahiko Negishi 10095 15545 5543 510 32.8k
Steven A. Kliewer 7926 32561 14227 166 55.4k
Allan H. Conney 8681 11549 4212 370 28.8k
Wayne Levin 11863 8640 4442 313 21.8k

All Works

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