Standout Papers

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 1993 2026 2004 2015 3.0k
  1. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 (1993)
    Manuel Serrano, Gregory J. Hannon et al. Nature
  2. p21 is a universal inhibitor of cyclin kinases (1993)
    Yue Xiong, Gregory J. Hannon et al. Nature
  3. pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest (1994)
    Gregory J. Hannon, David Beach Nature
  4. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA (1994)
    S Waga, Gregory J. Hannon et al. Nature
  5. Role of the INK4a Locus in Tumor Suppression and Cell Mortality (1996)
    Manuel Serrano, Han‐Woong Lee et al. Cell
  6. Senescence in premalignant tumours (2005)
    Manuel Collado, Jesús Gil et al. Nature
  7. Radiation-induced cell cycle arrest compromised by p21 deficiency (1995)
    James Brugarolas, Chitra Chandrasekaran et al. Nature
  8. Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD (1995)
    Orna Halevy, Bennett G. Novitch et al. Science
  9. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. (1995)
    Kay F. Macleod, Norelle L. Sherry et al. Genes & Development
  10. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA (1992)
    Yue Xiong, Hui Zhang et al. Cell
  11. A p16 INK4a -Insensitive CDK4 Mutant Targeted by Cytolytic T Lymphocytes in a Human Melanoma (1995)
    Thomas Wölfel, Jörg Schneider et al. Science
  12. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts (1996)
    David A. Alcorta, Yue Xiong et al. Proceedings of the National Academy of Sciences
  13. Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement (1988)
    Giulio Draetta, David Beach Cell
  14. Targeting CDK4 and CDK6: From Discovery to Therapy (2015)
    Charles J. Sherr, David Beach et al. Cancer Discovery
  15. Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator (1997)
    Neil D. Perkins, Lisa K. Felzien et al. Science
  16. Human D-type cyclin (1991)
    Yue Xiong, Bruce Futcher et al. Cell
  17. Cdc25 cell-cycle phosphatase as a target of c-myc (1996)
    Konstantin Galaktionov, David Beach et al. Nature
  18. cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF (1989)
    J M Westendorf, Leonardo Brizuela et al. Cell
  19. mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2 (1991)
    Karen Lundgren, Nancy C. Walworth et al. Cell
  20. p21-containing cyclin kinases exist in both active and inactive states. (1994)
    H Zhang, Greg Hannon et al. Genes & Development
  21. Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair (1994)
    Rong Li, S Waga et al. Nature
  22. Myc activates telomerase (1998)
    Jing Wang, Lin Xie et al. Genes & Development
  23. A Proinflammatory Cytokine Inhibits P53 Tumor Suppressor Activity (1999)
    James D. Hudson, M. A. Shoaibi et al. The Journal of Experimental Medicine
  24. Glycolytic Enzymes Can Modulate Cellular Life Span (2005)
    Hiroshi Kondoh, Matilde E. Lleonart et al. Cancer Research
  25. cdc2 is a component of the M phase-specific histone H1 kinase: Evidence for identity with MPF (1988)
    Dominique Arion, Laurent Meijer et al. Cell
  26. Functionally homologous cell cycle control genes in budding and fission yeast (1982)
    David Beach, Barbara W. Durkacz et al. Nature
  27. High-frequency transformation of the fission yeast Schizosaccharomyces pombe (1981)
    David Beach, Paul Nurse Nature
  28. Construction of a Schizosaccharomyces pombe gene bank in a yeast bacterial shuttle vector and its use to isolate genes by complementation (1982)
    David Beach, Melanie Piper et al. Molecular and General Genetics MGG

Immediate Impact

131 by Nobel laureates 117 from Science/Nature 233 standout
Sub-graph 1 of 9

Citing Papers

Neoantigens in cancer immunotherapy
2015 StandoutScience
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
4 intermediate papers

Works of David Beach being referenced

A High Glycolytic Flux Supports the Proliferative Potential of Murine Embryonic Stem Cells
2007
A p16 INK4a -Insensitive CDK4 Mutant Targeted by Cytolytic T Lymphocytes in a Human Melanoma
1995 StandoutScience

Author Peers

Author Last Decade Papers Cites
David Beach 34200 20131 9114 241 46.9k
Jiří Bártek 40971 22942 8164 378 52.8k
Charles J. Sherr 38985 30272 7513 270 57.5k
Frank McCormick 42325 14260 9298 376 56.7k
Gérard I. Evan 29571 11800 4210 244 42.5k
Mariano Barbacid 30539 14700 6107 262 51.4k
Michael B. Kastan 30153 18219 4001 153 38.5k
J. Wade Harper 48175 19357 11582 303 61.5k
Yue Xiong 23999 11215 4986 253 33.7k
Jiří Lukáš 30184 17547 6829 206 36.7k
Channing J. Der 35801 12591 10541 403 47.7k

All Works

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2026