Standout Papers

HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for... 2005 2026 2012 2019 3.0k
  1. HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia (2006)
    Jung‐whan Kim, Irina Tchernyshyov et al. Cell Metabolism
  2. Otto Warburg's contributions to current concepts of cancer metabolism (2011)
    Willem H. Koppenol, Patricia L. Bounds et al. Nature reviews. Cancer
  3. MYC on the Path to Cancer (2012)
    Chi V. Dang Cell
  4. c-Myc-regulated microRNAs modulate E2F1 expression (2005)
    Kathryn A. O’Donnell, Erik A. Wentzel et al. Nature
  5. c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism (2009)
    Ping Gao, Irina Tchernyshyov et al. Nature
  6. From Krebs to clinic: glutamine metabolism to cancer therapy (2016)
    Brian J. Altman, Zachary E. Stine et al. Nature reviews. Cancer
  7. c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism (1999)
    Chi V. Dang Molecular and Cellular Biology
  8. Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1 (2011)
    Eric V. Dang, Huang‐Yu Yang et al. Cell
  9. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression (2010)
    Anne Le, Charles R. Cooper et al. Proceedings of the National Academy of Sciences
  10. Widespread microRNA repression by Myc contributes to tumorigenesis (2007)
    Tsung-Cheng Chang, Duonan Yu et al. Nature Genetics
  11. Cancer's Molecular Sweet Tooth and the Warburg Effect (2006)
    Jung‐whan Kim, Chi V. Dang Cancer Research
  12. HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells (2007)
    Ryo Fukuda, Huafeng Zhang et al. Cell
  13. The c-Myc target gene network (2006)
    Chi V. Dang, Kathryn A. O’Donnell et al. Seminars in Cancer Biology
  14. MYC, Metabolism, and Cancer (2015)
    Zachary E. Stine, Zandra E. Walton et al. Cancer Discovery
  15. Oncogenic alterations of metabolism (1999)
    Chi V. Dang, Gregg L. Semenza Trends in Biochemical Sciences
  16. Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells (2012)
    Anne Le, Andrew N. Lane et al. Cell Metabolism
  17. c-Myc transactivation of LDH-A : Implications for tumor metabolism and growth (1997)
    Hyunsuk Shim, Christine Dolde et al. Proceedings of the National Academy of Sciences
  18. Links between metabolism and cancer (2012)
    Chi V. Dang Genes & Development
  19. HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity (2007)
    Huafeng Zhang, Ping Gao et al. Cancer Cell
  20. MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities (2009)
    Chi V. Dang, Anne Le et al. Clinical Cancer Research
  21. Targeting cancer metabolism in the era of precision oncology (2021)
    Zachary E. Stine, Zachary T. Schug et al. Nature Reviews Drug Discovery
  22. Deregulation of Glucose Transporter 1 and Glycolytic Gene Expression by c-Myc (2000)
    Hyunsuk Shim, Sunkyu Kim et al. Journal of Biological Chemistry
  23. Drugging the 'undruggable' cancer targets (2017)
    Chi V. Dang, E. Premkumar Reddy et al. Nature reviews. Cancer
  24. Multifaceted roles of glycolytic enzymes (2005)
    Jung‐whan Kim, Chi V. Dang Trends in Biochemical Sciences
  25. Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1 (2007)
    Jung‐whan Kim, Ping Gao et al. Molecular and Cellular Biology
  26. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth (2008)
    Huafeng Zhang, David Z. Qian et al. Proceedings of the National Academy of Sciences
  27. HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo (2007)
    Ping Gao, Huafeng Zhang et al. Cancer Cell
  28. The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer (2022)
    Gauri Mirji, Sajad A. Bhat et al. Science Immunology

Immediate Impact

71 by Nobel laureates 49 from Science/Nature 235 standout
Sub-graph 1 of 17

Citing Papers

Metabolic reprogramming and cancer progression
2020 StandoutScience
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
68 intermediate papers

Works of Chi V. Dang being referenced

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
and 47 more

Author Peers

Author Last Decade Papers Cites
Chi V. Dang 38321 23758 9323 299 52.1k
Matthew G. Vander Heiden 36431 25534 7132 218 53.1k
Amato J. Giaccia 22859 17174 10629 346 39.7k
M. Celeste Simon 25915 20715 7040 259 46.7k
William G. Kaelin 35237 22252 14721 244 49.6k
Ralph J. DeBerardinis 27775 19196 5080 230 41.4k
Jacques Pouysségur 28749 12099 6023 368 41.5k
Richard G. Pestell 32954 13379 15007 459 49.3k
Pier Paolo Pandolfi 61139 22576 12933 449 79.2k
John M. Asara 23820 11141 5099 287 35.5k
Scott W. Lowe 49438 16688 22670 324 68.3k

All Works

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2026