Yakov M. Koen

1.1k total citations
27 papers, 914 citations indexed

About

Yakov M. Koen is a scholar working on Molecular Biology, Pharmacology and Oncology. According to data from OpenAlex, Yakov M. Koen has authored 27 papers receiving a total of 914 indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 17 papers in Pharmacology and 7 papers in Oncology. Recurrent topics in Yakov M. Koen's work include Pharmacogenetics and Drug Metabolism (13 papers), Drug Transport and Resistance Mechanisms (7 papers) and Computational Drug Discovery Methods (7 papers). Yakov M. Koen is often cited by papers focused on Pharmacogenetics and Drug Metabolism (13 papers), Drug Transport and Resistance Mechanisms (7 papers) and Computational Drug Discovery Methods (7 papers). Yakov M. Koen collaborates with scholars based in United States, Russia and France. Yakov M. Koen's co-authors include Robert P. Hanzlik, Nadezhda A. Galeva, Todd D. Williams, Diganta Sarma, Heather Hajovsky, Jianwen Fang, Jeff L. Staudinger, Gang Hu, Wenqi Cui and Г.П. Кузнецова and has published in prestigious journals such as Journal of the American Chemical Society, SHILAP Revista de lepidopterología and Archives of Biochemistry and Biophysics.

In The Last Decade

Yakov M. Koen

27 papers receiving 902 citations

Peers

Yakov M. Koen
Kirk R. Henne United States
Jason Boer United States
Shawn Harriman United States
Patrick Porubsky United States
J S Miles United Kingdom
Stuart W. Paine United Kingdom
George Tonn United States
Hsia-lien Lin United States
Ken Grime United Kingdom
Kirk R. Henne United States
Yakov M. Koen
Citations per year, relative to Yakov M. Koen Yakov M. Koen (= 1×) peers Kirk R. Henne

Countries citing papers authored by Yakov M. Koen

Since Specialization
Citations

This map shows the geographic impact of Yakov M. Koen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yakov M. Koen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yakov M. Koen more than expected).

Fields of papers citing papers by Yakov M. Koen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yakov M. Koen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yakov M. Koen. The network helps show where Yakov M. Koen may publish in the future.

Co-authorship network of co-authors of Yakov M. Koen

This figure shows the co-authorship network connecting the top 25 collaborators of Yakov M. Koen. A scholar is included among the top collaborators of Yakov M. Koen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yakov M. Koen. Yakov M. Koen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hanzlik, Robert P., Yakov M. Koen, & Jianwen Fang. (2013). Bioinformatic Analysis of 302 Reactive Metabolite Target Proteins. Which Ones Are Important for Cell Death?. Toxicological Sciences. 135(2). 390–401. 14 indexed citations
2.
Koen, Yakov M., Diganta Sarma, Heather Hajovsky, et al.. (2013). Protein Targets of Thioacetamide Metabolites in Rat Hepatocytes. Chemical Research in Toxicology. 26(4). 564–574. 62 indexed citations
3.
Koen, Yakov M., Diganta Sarma, Todd D. Williams, et al.. (2012). Identification of Protein Targets of Reactive Metabolites of Tienilic Acid in Human Hepatocytes. Chemical Research in Toxicology. 25(5). 1145–1154. 12 indexed citations
4.
Koen, Yakov M., Heather Hajovsky, Ke Liu, et al.. (2012). Liver Protein Targets of Hepatotoxic 4-Bromophenol Metabolites. Chemical Research in Toxicology. 25(8). 1777–1786. 13 indexed citations
5.
Sarma, Diganta, Heather Hajovsky, Yakov M. Koen, et al.. (2012). Covalent Modification of Lipids and Proteins in Rat Hepatocytes and in Vitro by Thioacetamide Metabolites. Chemical Research in Toxicology. 25(9). 1868–1877. 25 indexed citations
6.
Hajovsky, Heather, Gang Hu, Yakov M. Koen, et al.. (2012). Metabolism and Toxicity of Thioacetamide and Thioacetamide S-Oxide in Rat Hepatocytes. Chemical Research in Toxicology. 25(9). 1955–1963. 164 indexed citations
7.
Fang, Jianwen, Yakov M. Koen, & Robert P. Hanzlik. (2009). Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners. SHILAP Revista de lepidopterología. 9(1). 5–5. 16 indexed citations
8.
Hanzlik, Robert P., Jianwen Fang, & Yakov M. Koen. (2008). Filling and mining the reactive metabolite target protein database. Chemico-Biological Interactions. 179(1). 38–44. 22 indexed citations
9.
Hanzlik, Robert P., et al.. (2007). The reactive metabolite target protein database (TPDB) – a web-accessible resource. BMC Bioinformatics. 8(1). 95–95. 29 indexed citations
10.
Ikehata, Keisuke, et al.. (2007). Covalent Modification of Microsomal Lipids by Thiobenzamide Metabolites in Vivo. Chemical Research in Toxicology. 20(4). 701–708. 27 indexed citations
11.
Koen, Yakov M., et al.. (2007). A Proteomic Analysis of Bromobenzene Reactive Metabolite Targets in Rat Liver Cytosol in Vivo. Chemical Research in Toxicology. 20(3). 511–519. 32 indexed citations
12.
Koen, Yakov M., et al.. (2005). Use of Isotopic Signatures for Mass Spectral Detection of Protein Adduction by Chemically Reactive Metabolites of Bromobenzene:  Studies with Model Proteins. Chemical Research in Toxicology. 18(11). 1748–1754. 9 indexed citations
13.
Lucas, Laura H., Matthew A. Cerny, Yakov M. Koen, Robert P. Hanzlik, & Cynthia K. Larive. (2004). 1H high-resolution magic-angle spinning (HR-MAS) NMR analysis of ligand density on resins using a resin internal standard. Analytical and Bioanalytical Chemistry. 380(4). 627–631. 6 indexed citations
14.
Koen, Yakov M., et al.. (2004). Synthesis of Nτ-arylhistidine derivatives via direct N-arylation. Bioorganic & Medicinal Chemistry Letters. 14(7). 1637–1640. 10 indexed citations
15.
Galeva, Nadezhda A., et al.. (2003). Direct Identification of Cytochrome P450 Isozymes by Matrix-assisted Laser Desorption/Ionization Time of Flight-Based Proteomic Approach. Drug Metabolism and Disposition. 31(4). 351–355. 20 indexed citations
16.
Davydov, Dmitri R., Tatyana V. Knyushko, Irina P. Kanaeva, et al.. (1996). Interactions of cytochrome P450 2B4 with NADPH-cytochrome P450 reductase studied by fluorescent probe. Biochimie. 78(8-9). 734–743. 27 indexed citations
17.
Davydov, Dmitri R., Eric Deprez, Gaston Hui Bon Hoa, et al.. (1995). High-pressure-induced transitions in microsomal cytochrome P450 2B4 in solution: Evidence for conformational inhomogeneity in the oligomers. Archives of Biochemistry and Biophysics. 320(2). 330–344. 98 indexed citations
18.
Kanaeva, Irina P., et al.. (1994). Catalytic Activity of Cytochrome P4501A2 in Reconstituted System with Emulgen 913. Archives of Biochemistry and Biophysics. 311(1). 133–143. 13 indexed citations
19.
Kanaeva, Irina P., et al.. (1992). Comparative study of monomeric reconstituted and membrane microsomal monooxygenase systems of the rabbit liver. Archives of Biochemistry and Biophysics. 298(2). 395–402. 44 indexed citations
20.
Kanaeva, Irina P., Dmitri R. Davydov, Yakov M. Koen, et al.. (1992). Comparative study of monomeric reconstituted and membrane microsomal monooxygenase systems of the rabbit liver. Archives of Biochemistry and Biophysics. 298(2). 403–412. 21 indexed citations

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