Hsia-lien Lin

979 total citations
26 papers, 799 citations indexed

About

Hsia-lien Lin is a scholar working on Pharmacology, Oncology and Molecular Biology. According to data from OpenAlex, Hsia-lien Lin has authored 26 papers receiving a total of 799 indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Pharmacology, 12 papers in Oncology and 9 papers in Molecular Biology. Recurrent topics in Hsia-lien Lin's work include Pharmacogenetics and Drug Metabolism (22 papers), Drug Transport and Resistance Mechanisms (11 papers) and Receptor Mechanisms and Signaling (4 papers). Hsia-lien Lin is often cited by papers focused on Pharmacogenetics and Drug Metabolism (22 papers), Drug Transport and Resistance Mechanisms (11 papers) and Receptor Mechanisms and Signaling (4 papers). Hsia-lien Lin collaborates with scholars based in United States, Australia and Italy. Hsia-lien Lin's co-authors include Paul F. Hollenberg, Ute M. Kent, Haoming Zhang, Lucy Waskell, Yoichi Osawa, Jan R. Crowley, Elizabeth S. Roberts, Haoming Zhang, Matthew Pratt–Hyatt and Leslie A. Parsels and has published in prestigious journals such as Biochemistry, Journal of Pharmacology and Experimental Therapeutics and Archives of Biochemistry and Biophysics.

In The Last Decade

Hsia-lien Lin

26 papers receiving 783 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hsia-lien Lin United States	17	467	249	217	114	107	26	799
Ylva Terelius Sweden	19	549 1.2×	420 1.7×	272 1.3×	198 1.7×	66 0.6×	33	1.3k
Sylvie Dijols France	18	571 1.2×	241 1.0×	250 1.2×	247 2.2×	180 1.7×	24	976
Craig B. Marcus United States	22	416 0.9×	542 2.2×	205 0.9×	107 0.9×	46 0.4×	51	1.4k
Maryse Jaouen France	16	385 0.8×	249 1.0×	228 1.1×	66 0.6×	70 0.7×	33	805
Sharon L. Ripp United States	22	569 1.2×	390 1.6×	269 1.2×	146 1.3×	100 0.9×	30	1.3k
David A. Tess United States	18	365 0.8×	296 1.2×	477 2.2×	42 0.4×	146 1.4×	45	1.1k
R. Foti United States	21	680 1.5×	408 1.6×	373 1.7×	98 0.9×	146 1.4×	51	1.3k
Steven J. Pernecky United States	11	419 0.9×	228 0.9×	196 0.9×	56 0.5×	77 0.7×	18	645
Tetsuya Kamataki Japan	16	589 1.3×	364 1.5×	273 1.3×	75 0.7×	37 0.3×	22	961
Zuyu Guo United States	18	507 1.1×	635 2.6×	212 1.0×	87 0.8×	72 0.7×	24	1.2k

Countries citing papers authored by Hsia-lien Lin

Since Specialization

Citations

This map shows the geographic impact of Hsia-lien Lin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hsia-lien Lin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hsia-lien Lin more than expected).

Fields of papers citing papers by Hsia-lien Lin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hsia-lien Lin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hsia-lien Lin. The network helps show where Hsia-lien Lin may publish in the future.

Co-authorship network of co-authors of Hsia-lien Lin

This figure shows the co-authorship network connecting the top 25 collaborators of Hsia-lien Lin. A scholar is included among the top collaborators of Hsia-lien Lin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hsia-lien Lin. Hsia-lien Lin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lin, Hsia-lien, et al.. (2017). Heme Modification Contributes to the Mechanism-Based Inactivation of Human Cytochrome P450 2J2 by Two Terminal Acetylenic Compounds. Drug Metabolism and Disposition. 45(9). 990–999. 15 indexed citations

Lin, Hsia-lien, et al.. (2013). The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir. Drug Metabolism and Disposition. 41(10). 1813–1824. 18 indexed citations

Lin, Hsia-lien, et al.. (2012). Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism. Drug Metabolism and Disposition. 41(1). 101–110. 14 indexed citations

Pratt–Hyatt, Matthew, Hsia-lien Lin, & Paul F. Hollenberg. (2010). Mechanism-Based Inactivation of Human CYP2E1 by Diethyldithocarbamate. Drug Metabolism and Disposition. 38(12). 2286–2292. 27 indexed citations

Lin, Hsia-lien, et al.. (2010). Covalent Modification of Thr302 in Cytochrome P450 2B1 by the Mechanism-Based Inactivator 4-tert-Butylphenylacetylene. Journal of Pharmacology and Experimental Therapeutics. 333(3). 663–669. 16 indexed citations

Lin, Hsia-lien, et al.. (2010). Inactivation of Cytochrome P450 (P450) 3A4 but not P450 3A5 by OSI-930, a Thiophene-Containing Anticancer Drug. Drug Metabolism and Disposition. 39(2). 345–350. 19 indexed citations

Zhang, Haoming, et al.. (2010). Targeting of the highly conserved threonine 302 residue of cytochromes P450 2B family during mechanism-based inactivation by aryl acetylenes. Archives of Biochemistry and Biophysics. 507(1). 135–143. 14 indexed citations

Lin, Hsia-lien, Haoming Zhang, Kathleen R. Noon, & Paul F. Hollenberg. (2009). Mechanism-Based Inactivation of CYP2B1 and Its F-Helix Mutant by Two tert-Butyl Acetylenic Compounds: Covalent Modification of Prosthetic Heme Versus Apoprotein. Journal of Pharmacology and Experimental Therapeutics. 331(2). 392–403. 10 indexed citations

Lin, Hsia-lien, Haoming Zhang, & Paul F. Hollenberg. (2009). Metabolic Activation of Mifepristone [RU486; 17β-Hydroxy-11β-(4-dimethylaminophenyl)-17α-(1-propynyl)-estra-4,9-dien-3-one] by Mammalian Cytochromes P450 and the Mechanism-Based Inactivation of Human CYP2B6. Journal of Pharmacology and Experimental Therapeutics. 329(1). 26–37. 16 indexed citations

10.

Zhang, Haoming, et al.. (2009). tert-Butylphenylacetylene Is a Potent Mechanism-Based Inactivator of Cytochrome P450 2B4: Inhibition of Cytochrome P450 Catalysis by Steric Hindrance. Molecular Pharmacology. 76(5). 1011–1018. 23 indexed citations

11.

Lin, Hsia-lien & Paul F. Hollenberg. (2007). The Inactivation of Cytochrome P450 3A5 by 17α-Ethynylestradiol Is Cytochrome b5-Dependent: Metabolic Activation of the Ethynyl Moiety Leads to the Formation of Glutathione Conjugates, a Heme Adduct, and Covalent Binding to the Apoprotein. Journal of Pharmacology and Experimental Therapeutics. 321(1). 276–287. 24 indexed citations

12.

Kent, Ute M., Hsia-lien Lin, Kathleen R. Noon, Danni L. Harris, & Paul F. Hollenberg. (2006). Metabolism of Bergamottin by Cytochromes P450 2B6 and 3A5. Journal of Pharmacology and Experimental Therapeutics. 318(3). 992–1005. 29 indexed citations

13.

Kent, Ute M., et al.. (2006). Identification of 17-α-Ethynylestradiol-Modified Active Site Peptides and Glutathione Conjugates Formed during Metabolism and Inactivation of P450s 2B1 and 2B6. Chemical Research in Toxicology. 19(2). 279–287. 25 indexed citations

14.

Lin, Hsia-lien, Ute M. Kent, & Paul F. Hollenberg. (2005). The Grapefruit Juice Effect Is Not Limited to Cytochrome P450 (P450) 3A4: Evidence for Bergamottin-Dependent Inactivation, Heme Destruction, and Covalent Binding to Protein in P450s 2B6 and 3A5. Journal of Pharmacology and Experimental Therapeutics. 313(1). 154–164. 72 indexed citations

15.

Lin, Hsia-lien, Ute M. Kent, Haoming Zhang, Lucy Waskell, & Paul F. Hollenberg. (2004). The Functional Role of Threonine-205 in the Mechanism-Based Inactivation of P450 2B1 by Two Ethynyl Substrates: The Importance of the F Helix in Catalysis. Journal of Pharmacology and Experimental Therapeutics. 311(3). 855–863. 8 indexed citations

16.

Lin, Hsia-lien, Ute M. Kent, & Paul F. Hollenberg. (2002). Mechanism-Based Inactivation of Cytochrome P450 3A4 by 17α-Ethynylestradiol: Evidence for Heme Destruction and Covalent Binding to Protein. Journal of Pharmacology and Experimental Therapeutics. 301(1). 160–167. 106 indexed citations

17.

Lin, Hsia-lien & Paul F. Hollenberg. (2001). N-Nitrosodimethylamine-Mediated Formation of Oxidized and Methylated DNA Bases in a Cytochrome P450 2E1 Expressing Cell Line. Chemical Research in Toxicology. 14(5). 562–566. 46 indexed citations

18.

Lin, Hsia-lien, Leslie A. Parsels, Jonathan Maybaum, & Paul F. Hollenberg. (1999). N-Nitrosodimethylamine-Mediated Cytotoxicity in a Cell Line Expressing P450 2E1: Evidence for Apoptotic Cell Death. Toxicology and Applied Pharmacology. 157(2). 117–124. 43 indexed citations

19.

Roberts, Elizabeth S., et al.. (1998). Peroxynitrite-Mediated Nitration of Tyrosine and Inactivation of the Catalytic Activity of Cytochrome P450 2B1. Chemical Research in Toxicology. 11(9). 1067–1074. 88 indexed citations

20.

Lin, Hsia-lien, Nicola C. Day, Yasuko Ueda, et al.. (1993). Tissue-Specific and Substrate-Specific Endoproteolytic Cleavage of Monkey Pro-Opiomelanocortin in Heterologous Endocrine Cells: Processing at Lys-Lys Dibasic Pairs. Neuroendocrinology. 58(1). 94–105. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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