Xilin Lyu

875 total citations
24 papers, 696 citations indexed

About

Xilin Lyu is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Xilin Lyu has authored 24 papers receiving a total of 696 indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 8 papers in Oncology and 7 papers in Cancer Research. Recurrent topics in Xilin Lyu's work include Ubiquitin and proteasome pathways (7 papers), Protein Degradation and Inhibitors (5 papers) and Cancer-related Molecular Pathways (5 papers). Xilin Lyu is often cited by papers focused on Ubiquitin and proteasome pathways (7 papers), Protein Degradation and Inhibitors (5 papers) and Cancer-related Molecular Pathways (5 papers). Xilin Lyu collaborates with scholars based in China, Germany and United States. Xilin Lyu's co-authors include Fengtian He, Gang Huang, Zhenhong Ni, Haojun Xiong, Xiao Li, Bin Li, Jianzhong He, Weijuan Gong, Biao Chen and S Chen and has published in prestigious journals such as Oncogene, Journal of Medicinal Chemistry and Molecules.

In The Last Decade

Xilin Lyu

22 papers receiving 690 citations

Peers

Countries citing papers authored by Xilin Lyu

Since Specialization

Citations

This map shows the geographic impact of Xilin Lyu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xilin Lyu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xilin Lyu more than expected).

Fields of papers citing papers by Xilin Lyu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xilin Lyu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xilin Lyu. The network helps show where Xilin Lyu may publish in the future.

Co-authorship network of co-authors of Xilin Lyu

This figure shows the co-authorship network connecting the top 25 collaborators of Xilin Lyu. A scholar is included among the top collaborators of Xilin Lyu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xilin Lyu. Xilin Lyu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Synthesis of an RBM39 Degrader That Downregulates CEP192 and Induces Disorganized Spindle Structures 2025 ·Journal of Medicinal Chemistry ·Xilin Lyu, Xiancheng Wang, (unknown), Yuhan Lu, Chenxu Wang, Ziqin Yan, Zhiyi Wang, Ying Cheng, Jing Cheng, Xuelian Ren, Yi Su, (unknown), Yi Chen, He Huang, Yujun Zhao	0
2	Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach 2024 ·Journal of Medicinal Chemistry ·(unknown), Lijian Feng, (unknown), Ziqin Yan, Xilin Lyu, Kaige Li, (unknown), (unknown), Weiwei Lu, Chao Wang, (unknown), (unknown), (unknown), Yingjie Li, Yujun Zhao, Zhiqiang Duan, Jidong Zhu, Xiaojie Lu	4
3	Synthesis and biological evaluation of 4-imidazolidinone–containing compounds as potent inhibitors of the MDM2/p53 interaction 2024 ·European Journal of Medicinal Chemistry ·(unknown), Chen Liu, Ziqin Yan, (unknown), Xiancheng Wang, Feilong Zhou, Xilin Lyu, Shiyan Zhang, Daizhou Zhang, Xiangjing Meng, Yujun Zhao	3
4	Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1 2024 ·Journal of Medicinal Chemistry ·(unknown), (unknown), Xilin Lyu, (unknown), Chen Liu, Ziqin Yan, Yan Li, (unknown), (unknown), Jian Ding, Ye Lu, He Huang, Hua Xie, Yujun Zhao	5
5	Structure-based optimization of indoline-containing compounds as second generation inhibitors of NF-κB-inducing kinase (NIK) 2023 ·Journal of Molecular Structure ·Jing Cheng, Ziqin Yan, Xinzhi Li, Chen Liu, Linjiang Tong, Xilin Lyu, Bingjie Yang, Zheng Chen, Yujun Zhao	0
6	Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines 2023 ·European Journal of Medicinal Chemistry ·Ziqin Yan, Xilin Lyu, (unknown), (unknown), Gong Yang, Xuelian Ren, Jian Xiao, (unknown), He Huang, Yi Chen, Yujun Zhao	9
7	Synthesis and Biological Evaluation of Sclareolide-Indole Conjugates and Their Derivatives 2023 ·Molecules ·Ying Cheng, Xilin Lyu, Chen Liu, Xiancheng Wang, Jing Cheng, Daizhou Zhang, Xiangjing Meng, Yujun Zhao	2
8	Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein–Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 2023 ·Journal of Medicinal Chemistry ·(unknown), Ziqin Yan, (unknown), Chen Liu, Dehua Xu, Xilin Lyu, Xiaobei Hu, Shiyan Zhang, Yubo Zhou, Jia Li, Yujun Zhao	11
9	Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells 2022 ·European Journal of Medicinal Chemistry ·(unknown), Ziqin Yan, Feilong Zhou, (unknown), Xilin Lyu, Xuelian Ren, Ziyu Zeng, Chenglong Liu, Shiyan Zhang, Di Zhu, He Huang, Jinming Yang, Yujun Zhao	7
10	Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine 2021 ·Journal of Molecular Structure ·Xian Zhou, (unknown), (unknown), Deheng Chen, (unknown), Ziqin Yan, Xilin Lyu, Huan Wang, Jinming Yang, Yujun Zhao	3
11	Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein–Protein Interactions 2021 ·Journal of Medicinal Chemistry ·Shiyan Zhang, (unknown), Yafang Li, Feilong Zhou, Ziqin Yan, Xilin Lyu, Yujun Zhao	32
12	Upregulation of miR-124-3p by Liver X Receptor Inhibits the Growth of Hepatocellular Carcinoma Cells Via Suppressing Cyclin D1 and CDK6 2020 ·Technology in Cancer Research & Treatment ·Dan Zhong, Xilin Lyu, Xiaohong Fu, Peng Xie, (unknown), Fengtian He, Gang Huang	8
13	Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1) 2020 ·European Journal of Medicinal Chemistry ·Shiyan Zhang, (unknown), Xilin Lyu, Peipei Wang, Yi Zang, Zengtao Wang, Huan Wang, Jia Li, Yujun Zhao	10
14	Chlorogenic Acid Inhibits BAFF Expression in Collagen-Induced Arthritis and Human Synoviocyte MH7A Cells by Modulating the Activation of the NF-κB Signaling Pathway 2019 ·Journal of Immunology Research ·Xiaohong Fu, Xilin Lyu, Han Liu, Dan Zhong, Zhizhen Xu, Fengtian He, Gang Huang	33
15	Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins 2019 ·European Journal of Medicinal Chemistry ·Deheng Chen, Tian Lu, Ziqin Yan, Wenchao Lu, Feilong Zhou, Xilin Lyu, (unknown), Hualiang Jiang, Kaixian Chen, Cheng Luo, Yujun Zhao	45
16	Metformin Synergizes with BCL-XL/BCL-2 Inhibitor ABT-263 to Induce Apoptosis Specifically in p53-Defective Cancer Cells 2017 ·Molecular Cancer Therapeutics ·Xinzhe Li, Bo Li, Zhenhong Ni, Peng Zhou, Bin Wang, (unknown), Haojun Xiong, Fan Yang, Yaran Wu, Xilin Lyu, Yan Zhang, Yijun Zeng, Jiqin Lian, Fengtian He	18
17	LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells 2017 ·Oncogene ·Haojun Xiong, Zhenhong Ni, Jianzhong He, (unknown), Xiao Li, Weijuan Gong, Lei Zheng, S Chen, Bin Li, Ning Zhang, Xilin Lyu, Gang Huang, Biao Chen, (unknown), Fengtian He	311
18	HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells 2017 ·Cancer Letters ·Nan Zhang, Yaran Wu, Xilin Lyu, Bo Li, Xiaojing Yan, Haojun Xiong, Xinzhe Li, Gang Huang, Yijun Zeng, Yan Zhang, Jiqin Lian, Zhenhong Ni, Fengtian He	38
19	Activation of LXR attenuates collagen-induced arthritis via suppressing BLyS production 2015 ·Clinical Immunology ·Yan Huang, Xiaohong Fu, Xilin Lyu, Zhizhen Xu, Zhicheng He, Yan Zhang, Yijun Zeng, Fengtian He, Gang Huang	19
20	FXR induces SOCS3 and suppresses hepatocellular carcinoma 2015 ·Oncotarget ·Fei Guo, Zhizhen Xu, Yan Zhang, Peng Jiang, Gang Huang, Shan Chen, Xilin Lyu, Ping Zheng, Xin Zhao, Yijun Zeng, Shuguang Wang, Fengtian He	46

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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