Xiao-Feng Le

1.6k citations

23 papers · 1.3k indexed · h-index 21

Impact in

Cancer Research top 10%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
Oncology top 5%
- HER2/EGFR in Cancer Research
- Cancer-related Molecular Pathways

Papers in

Oncology 9
- Cancer-related Molecular Pathways 7
- HER2/EGFR in Cancer Research 6
Cell Biology 5
- Microtubule and mitosis dynamics 5

Co-authors: Robert C. Bast Kun-Sang Chang Peirong Yang Weiqun Mao Mien‐Chie Hung George A. Calin François-Xavier Claret Sadeq Vallian
Journals: Cell Cycle (3 papers)Journal of Biological Chemistry (3 papers)Oncogene (3 papers)Clinical Cancer Research (2 papers)Cancer Research (2 papers)
Partner nations: United States China Hong Kong

In The Last Decade

Xiao-Feng Le

23 papers receiving 1.3k citations

Peers

Countries citing papers authored by Xiao-Feng Le

Since Specialization

Citations

This map shows the geographic impact of Xiao-Feng Le's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xiao-Feng Le with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xiao-Feng Le more than expected).

Fields of papers citing papers by Xiao-Feng Le

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xiao-Feng Le. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xiao-Feng Le. The network helps show where Xiao-Feng Le may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Xiao-Feng Le, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xiao-Feng Le Line = papers co-authored together Xiao-Feng Le links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Jab1/Csn5–Thioredoxin Signaling in Relapsed Acute Monocytic Leukemia under Oxidative Stress Clinical Cancer Research ·Fuling Zhou, Yunbao Pan, Yongchang Wei, Ronghua Zhang, KyeoReh Lee, Shangde Cai, Shan Meng, Xiao-Feng Le, Michael Andreeff, François X. Claret	2017	52
2	Clinically Relevant microRNAs in Ovarian Cancer Molecular Cancer Research ·Shu Zhang, Zhen Lü, Anna K. Unruh, Cristina Ivan, Keith Baggerly, George A. Călin, Zongfang Li, Robert C. Bast, Xiao-Feng Le	2014	70
3	ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells Journal of Hematology & Oncology ·Christine M. Stellrecht, Hima V. Vangapandu, Xiao-Feng Le, Weiqun Mao, Shujun Shentu	2014	30
4	Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling International Journal of Oncology ·Keyvan Hashtrudi‐Zaad, Shu Zhang, Graciela Echeverria, Jihan Nurhaliza, Jun Li, A. Isiaka, Chen Huang, Xiao-Feng Le, Jun Yang, Fernandes Pereira Francisco	2012	55
5	Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel Cancer Research ·Ahmed A. Ahmed, Xiaoyan Wang, Zhen Lü, Juliet Goldsmith, Xiao-Feng Le, Geoffrey Grandjean, Geoffrey Bartholomeusz, Bradley M. Broom, Robert C. Bast	2011	45
6	iASPP and Chemoresistance in Ovarian Cancers: Effects on Paclitaxel-Mediated Mitotic Catastrophe Clinical Cancer Research ·Magdalena Grajek, Michelle K.Y. Siu, Oscar Gee‐Wan Wong, L.M. Duizer, Xin Lü, Eric W.‐F. Lam, Hys Ngan, Xiao-Feng Le, Esther S.Y. Wong, Lara J. Monteiro, Antoni Riera Font, Any Cheung	2011	63
7	Src family kinases and paclitaxel sensitivity Cancer Biology & Therapy ·Xiao-Feng Le, Robert C. Bast	2011	69
8	Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival Histopathology ·Yue-You Chen, Michelle K.Y. Siu, Lili Jiang, Kar Fai Tam, Hys Ngan, Xiao-Feng Le, Oscar Gee‐Wan Wong, Esther S.Y. Wong, Chy Chan, Any Cheung	2011	16
9	The Role of p27 Kip1 in Dasatinib-Enhanced Paclitaxel Cytotoxicity in Human Ovarian Cancer Cells JNCI Journal of the National Cancer Institute ·Xiao-Feng Le, Weiqun Mao, Guangan He, François-Xavier Claret, Weiya Xia, Ahmed A. Ahmed, Mien‐Chie Hung, Zahid H. Siddik, Robert C. Bast	2011	23
10	A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway Cancer Letters ·K. J. Frost, Ting Yu, 李静霞, Chao Feng, M. Tayal, Xiufeng Liu, Donald C. Chang, Xiao-Feng Le, Kathy Qian Luo	2010	50
11	Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2 Cell Cycle ·Xiao-Feng Le, Weiqun Mao, Chunhua Lu, Angela Thornton, John V. Heymach, Anil K. Sood, Robert C. Bast	2008	45
12	Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells Molecular Cancer Therapeutics ·Xiao-Feng Le, Hadas Shejtman, Weiqun Mao, Mary C. Horne, Robert C. Bast	2007	37
13	Anti-HER2 Antibody Trastuzumab Inhibits CDK2-Mediated NPAT and Histone H4 Expression via PI3K Pathway Cell Cycle ·Xiao-Feng Le, акмал қувондиқов, Weiqun Mao, In Gyu Yang, Zhen Lü, Khandan Keyomarsi, Mong‐Hong Lee, Jiyong Zhao, Robert C. Bast	2006	20
14	HER2-targeting Antibodies Modulate the Cyclin-dependent Kinase Inhibitor p27Kip1 via Multiple Signaling Pathways Cell Cycle ·Xiao-Feng Le, Michal Etzion, Robert C. Bast	2004	114
15	The Role of Cyclin-dependent Kinase Inhibitor p27Kip1 in Anti-HER2 Antibody-induced G1 Cell Cycle Arrest and Tumor Growth Inhibition Journal of Biological Chemistry ·Xiao-Feng Le, François-Xavier Claret, 哲士広田, Ling Tian, Deepa Deshpande, Ruth LaPushin, Ana M. Tari, Robert C. Bast	2003	123
16	Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis Oncogene ·Xiao-Feng Le, Walter N. Hittelman, Jiaxin Liu, Amanda McWatters, Chun Li, Gordon B. Mills, Robert C. Bast	2003	50
17	Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C α activity Oncogene ·Xiao-Feng Le, Marco Marcelli, Amanda McWatters, Bicheng Nan, Gordon B. Mills, Catherine A. O’Brian, Robert C. Bast	2001	39
18	Regulation of AML2/CBFA3 in Hematopoietic Cells through the Retinoic Acid Receptor α-Dependent Signaling Pathway Journal of Biological Chemistry ·Xiao-Feng Le, Yoram Groner, Steve Kornblau, Yun Gu, Walter N. Hittelman, Ditsa Levanon, Kapil Mehta, Ralph B. Arlinghaus, Kun-Sang Chang	1999	50
19	Analysis of the Growth and Transformation Suppressor Domains of Promyelocytic Leukemia Gene, PML Journal of Biological Chemistry ·Xiao-Feng Le, Peirong Yang, Kun-Sang Chang	1996	113
20	The Biologic Function of PML and its Role in Acute Promyelocytic Leukemia Leukemia & lymphoma ·Tomek Korbak, Xiao-Feng Le, Armand B. Glassman, Kun‐Sang Chang	1996	18

About Xiao-Feng Le

Xiao-Feng Le is a scholar working on Oncology, Cell Biology, Hematology, Molecular Biology and Physiology, having authored 23 papers that have together received 1.3k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (7 papers), HER2/EGFR in Cancer Research (6 papers), Microtubule and mitosis dynamics (5 papers), Retinoids in leukemia and cellular processes (4 papers), Acute Myeloid Leukemia Research (3 papers), MicroRNA in disease regulation (2 papers), PI3K/AKT/mTOR signaling in cancer (2 papers) and Protein Kinase Regulation and GTPase Signaling (2 papers). The work is most often cited by research in Cancer Research (274 citations), Oncology (462 citations), Molecular Biology (910 citations), Hematology (132 citations) and Radiology, Nuclear Medicine and Imaging (155 citations). Xiao-Feng Le has collaborated with scholars based in United States, China and Hong Kong. Frequent co-authors include Robert C. Bast, Kun-Sang Chang, Peirong Yang, Weiqun Mao, Mien‐Chie Hung, George A. Calin, François-Xavier Claret, Sadeq Vallian, Ana M. Tari and Ruth LaPushin. Their work appears in journals such as Cell Cycle, Journal of Biological Chemistry, Oncogene, Clinical Cancer Research and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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