William J. Brock

955 total citations
41 papers, 671 citations indexed

About

William J. Brock is a scholar working on Genetics, Molecular Biology and Oncology. According to data from OpenAlex, William J. Brock has authored 41 papers receiving a total of 671 indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Genetics, 8 papers in Molecular Biology and 8 papers in Oncology. Recurrent topics in William J. Brock's work include Carcinogens and Genotoxicity Assessment (8 papers), Drug Transport and Resistance Mechanisms (7 papers) and Animal testing and alternatives (7 papers). William J. Brock is often cited by papers focused on Carcinogens and Genotoxicity Assessment (8 papers), Drug Transport and Resistance Mechanisms (7 papers) and Animal testing and alternatives (7 papers). William J. Brock collaborates with scholars based in United States, Japan and Spain. William J. Brock's co-authors include D. B. Warheit, K. L. Reed, Mary Vore, Kim L. R. Brouwer, Sharin E. Roth, Paul B. Watkins, Merrie Mosedale, Henry J. Trochimowicz, James J. Beaudoin and J. Scott Eaddy and has published in prestigious journals such as Journal of Pharmacology and Experimental Therapeutics, British Journal of Pharmacology and Carcinogenesis.

In The Last Decade

William J. Brock

40 papers receiving 639 citations

Peers

Countries citing papers authored by William J. Brock

Since Specialization

Citations

This map shows the geographic impact of William J. Brock's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William J. Brock with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William J. Brock more than expected).

Fields of papers citing papers by William J. Brock

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William J. Brock. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William J. Brock. The network helps show where William J. Brock may publish in the future.

Co-authorship network of co-authors of William J. Brock

This figure shows the co-authorship network connecting the top 25 collaborators of William J. Brock. A scholar is included among the top collaborators of William J. Brock based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William J. Brock. William J. Brock is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Translation From Ophthalmic Research to Ophthalmic Products 2025 ·American Journal of Ophthalmology ·Gary D. Novack, William J. Brock, (unknown)	0
2	A weight of evidence evaluation of the mode of action of isoeugenol 2024 ·Regulatory Toxicology and Pharmacology ·William J. Brock, (unknown), Cynthia Van Landingham, Robinan Gentry	1
3	Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease 2019 ·Drug Metabolism and Disposition ·Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock, Kim L. R. Brouwer	16
4	Bile Acids as Potential Biomarkers to Assess Liver Impairment in Polycystic Kidney Disease 2018 ·International Journal of Toxicology ·William J. Brock, James J. Beaudoin, (unknown), Mingming Su, Wei Jia, Sharin E. Roth, Kim L. R. Brouwer	16
5	miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model 2017 ·Toxicological Sciences ·Merrie Mosedale, J. Scott Eaddy, O. Joseph Trask, (unknown), Kristina Wolf, Edward L. LeCluyse, Brenton R. Ware, Salman R. Khetani, Jingtao Lu, William J. Brock, Sharin E. Roth, Paul B. Watkins	40
6	Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors 2016 ·Toxicological Sciences ·Jeffrey L. Woodhead, William J. Brock, Sharin E. Roth, Susan E. Shoaf, Kim L. R. Brouwer, Rachel J. Church, Tom N. Grammatopoulos, Linsey Stiles, Scott Q. Siler, Brett A. Howell, Merrie Mosedale, Paul B. Watkins, Lisl K.M. Shoda	71
7	Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes 2016 ·Drug Metabolism and Disposition ·Yang Lu, (unknown), Kenneth R. Brouwer, (unknown), Kimberly Freeman, Min Pan, William J. Brock, Kim L. R. Brouwer	16
8	Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach 2016 ·Toxicological Sciences ·Merrie Mosedale, Yunjung Kim, William J. Brock, Sharin E. Roth, Tim Wiltshire, J. Scott Eaddy, Gregory R. Keele, Robert W. Corty, Yuying Xie, William Valdar, Paul B. Watkins	38
9	Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury? 2015 ·Toxicological Sciences ·(unknown), Yang Lu, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly Freeman, (unknown), William J. Brock, Kim L. R. Brouwer	40
10	Comparative Pulmonary Toxicity Inhalation and Instillation Studies with Different TiO2 Particle Formulations: Impact of Surface Treatments on Particle Toxicity 2005 ·Toxicological Sciences ·D. B. Warheit, William J. Brock, (unknown), (unknown), K. L. Reed	170
11	Cardiac sensitization: methodology and interpretation in risk assessment 2003 ·Regulatory Toxicology and Pharmacology ·William J. Brock, George M. Rusch, Henry J. Trochimowicz	12
12	Developmental Toxicity and Genotoxicity Studies of 1,1,1,3,3,3-Hexachloropropane (HCC-230fa) in Rats 2003 ·Toxicological Sciences ·William J. Brock	2
13	EFFECTS OF HCFC-123 EXPOSURE TO MATERNAL AND INFANT RHESUS MONKEYS ON HEPATIC BIOCHEMISTRY, LACTATIONAL PARAMETERS AND POSTNATAL GROWTH 2002 ·Drug and Chemical Toxicology ·Gregg D. Cappon, Douglas A. Keller, William J. Brock, (unknown), Mark E. Hurtt	3
14	Subchronic Inhalation Toxicity of the Chlorinated Propane 1,1,1,3,3,3-Hexachloropropane (HCC-230fa) 2001 ·Toxicological Sciences ·(unknown), Gregory S. Ladics, Mark E. Hurtt, Mark S. Swanson, William J. Brock	2
15	Inhalation toxicity and genotoxicity of hydrochlorofluorocarbon (HCFC)-225ca and HCFC-225cb 1999 ·Journal of Applied Toxicology ·William J. Brock, (unknown), George M. Rusch, Colin Hardy, Henry J. Trochimowicz	2
16	1,1,1-Trifluoro-2,2-dichloroethane (HCFC-123) and 1,1,1-Trifluoro-2-bromo-2-chloroethane (Halothane) Cause Similar Biochemical Effects in Rats Exposed by Inhalation for Five Days 1998 ·Drug and Chemical Toxicology ·Douglas A. Keller, Paul H. Lieder, William J. Brock, Jon C. Cook	4
17	Hepatic macromolecular binding and tissue distribution of ortho- and para-toluidine in rats 1990 ·Toxicology Letters ·William J. Brock, (unknown), Paul H. Lieder	12
18	Characterization of the interaction between estrogen metabolites and taurocholate for uptake into isolated hepatocytes. Lack of correlation between cholestasis and inhibition of taurocholate uptake 1984 ·Journal of Steroid Biochemistry ·William J. Brock, (unknown), Mary Vore	8
19	The effect of pregnancy and treatment with 17 beta-estradiol on the transport of organic anions into isolated rat hepatocytes. 1984 ·Drug Metabolism and Disposition ·William J. Brock, Mary Vore	12
20	Hepatic morphine and estrone glucuronyltransferase activity and morphine biliary excretion in the isolated perfused rat liver. Effect of pregnancy and estradiol-17 beta treatment. 1982 ·Drug Metabolism and Disposition ·William J. Brock, Mary Vore	9

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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