William G. Fairbrother

4.8k citations

48 papers · 3.0k indexed · 1 hit paper · h-index 25

Molecular Biology top 5%
- RNA Research and Splicing 35
- RNA modifications and cancer 29
- RNA and protein synthesis mechanisms 23
- Genomics and Chromatin Dynamics 4
- CRISPR and Genetic Engineering 3
Cancer Research top 5%
- Cancer-related molecular mechanisms research 4
Genetics top 5%
- Neurogenetic and Muscular Disorders Research 3
Genetics top 5%
- Neurogenetic and Muscular Disorders Research 3
Cardiology and Cardiovascular Medicine top 10%
Infectious Diseases
- SARS-CoV-2 and COVID-19 Research 2

Co-authors: Phillip A. Sharp Christopher B. Burge Ru‐Fang Yeh Kamil J. Cygan Kian‐Huat Lim Allison J. Taggart Lawrence A. Chasin Benjamin J. Raphael
Cited by: Molecular Biology Cancer Research Genetics
Journals: Science (1 paper)Proceedings of the National Academy of Sciences (2 papers)Nucleic Acids Research (3 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

William G. Fairbrother

47 papers receiving 2.9k citations

Hit Papers

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Peers

Countries citing papers authored by William G. Fairbrother

Since Specialization

Citations

This map shows the geographic impact of William G. Fairbrother's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William G. Fairbrother with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William G. Fairbrother more than expected).

Fields of papers citing papers by William G. Fairbrother

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William G. Fairbrother. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William G. Fairbrother. The network helps show where William G. Fairbrother may publish in the future.

Co-authorship network

The 25 scholars most cited alongside William G. Fairbrother, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William G. Fairbrother Line = papers co-authored together William G. Fairbrother links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The debranching enzyme Dbr1 regulates lariat turnover and intron splicing Nature Communications ·Luke Buerer,Nathaniel E. Clark,Anastasia Welch,Chaorui Duan,Allison J. Taggart,Brittany A. Townley,Jing Wang,Rachel Soemedi,Stephen Rong,Chien‐Ling Lin,Yi Zeng,Adam Katolik,Jonathan P. Staley,Masad J. Damha,Nima Mosammaparast,William G. Fairbrother	2024	8
2	Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain Journal of Biological Chemistry ·Nathaniel E. Clark,Adam Katolik,Pascal Gallant,Anastasia Welch,E. Murphy,Luke Buerer,Christoph Schorl,Nandita Naik,Mandar T. Naik,S. Holloway,Kristin E. Cano,Susan T. Weintraub,Katherine M. Howard,P. John Hart,G. Jogl,Masad J. Damha,William G. Fairbrother	2023	3
3	Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1 RNA ·Nathaniel E. Clark,Adam Katolik,Allison J. Taggart,Luke Buerer,S. Holloway,Nathan Miller,John D. Phillips,Colin Farrell,Masad J. Damha,William G. Fairbrother	2022	6
4	Deep RNA sequencing of intensive care unit patients with COVID-19 Scientific Reports ·Alger M. Fredericks,Maximilian S. Jentzsch,William G. Cioffi,Maya Cohen,William G. Fairbrother,Shivam J. Gandhi,Elizabeth O. Harrington,Gerard J. Nau,Jonathan S. Reichner,Corey E. Ventetuolo,Mitchell M. Levy,Alfred Ayala,Sean F. Monaghan	2022	8
5	Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations Frontiers in Molecular Biosciences ·Alger M. Fredericks,Kyle W. East,Yuanjun Shi,Jinchan Liu,Federica Maschietto,Alfred Ayala,William G. Cioffi,Maya Cohen,William G. Fairbrother,Craig T. Lefort,Gerard J. Nau,Mitchell M. Levy,Jimin Wang,Víctor S. Batista,George P. Lisi,Sean F. Monaghan	2022	3
6	Mutational bias and the protein code shape the evolution of splicing enhancers Nature Communications ·Stephen Rong,Luke Buerer,Christy L. Rhine,Jing Wang,Kamil J. Cygan,William G. Fairbrother	2020	15
7	MMSplice: modular modeling improves the predictions of genetic variant effects on splicing Genome biology ·Jun Cheng,Thi Yen Duong Nguyen,Kamil J. Cygan,Muhammed Hasan Çelik,William G. Fairbrother,Žiga Avsec,Julien Gagneur	2019	125
8	Hereditary cancer genes are highly susceptible to splicing mutations PLoS Genetics ·Christy L. Rhine,Kamil J. Cygan,Rachel Soemedi,Samantha Maguire,Michael F. Murray,Sean F. Monaghan,William G. Fairbrother	2018	37
9	Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness Molecular Medicine ·Sean F. Monaghan,Debasree Banerjee,Chun‐Shiang Chung,Joanne Lomas‐Neira,Kamil J. Cygan,Christy L. Rhine,William G. Fairbrother,Daithi S. Heffernan,Mitchell M. Levy,William G. Cioffi,Alfred Ayala	2018	24
10	Defective splicing of the RB1 transcript is the dominant cause of retinoblastomas Human Genetics ·Kamil J. Cygan,Rachel Soemedi,Christy L. Rhine,Abraham Profeta,E. Murphy,Michael F. Murray,William G. Fairbrother	2017	5
11	Pathogenic variants that alter protein code often disrupt splicing Nature Genetics ·Rachel Soemedi,Kamil J. Cygan,Christy L. Rhine,Jing Wang,Charlston Bulacan,John Yang,Pınar Bayrak‐Toydemir,Jamie McDonald,William G. Fairbrother	2017	151
12	Widespread intra-dependencies in the removal of introns from human transcripts Nucleic Acids Research ·Seong Won Kim,Allison J. Taggart,Claire Heintzelman,Kamil J. Cygan,Caitlin G. Hull,Jing Wang,Barsha Shrestha,William G. Fairbrother	2017	41
13	Large-scale analysis of branchpoint usage across species and cell lines Genome Research ·Allison J. Taggart,Chien‐Ling Lin,Barsha Shrestha,Claire Heintzelman,Seong Won Kim,William G. Fairbrother	2017	84
14	RNA structure replaces the need for U2AF2 in splicing Genome Research ·Chien‐Ling Lin,Allison J. Taggart,Kian‐Huat Lim,Kamil J. Cygan,Luciana Ferraris,Robbert Créton,Yen‐Tsung Huang,William G. Fairbrother	2015	24
15	Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo Nature Structural & Molecular Biology ·Allison J. Taggart,Alec M. DeSimone,Janice S Shih,Madeleine E. Filloux,William G. Fairbrother	2012	91
16	Combinatorial binding of transcription factors in the pluripotency control regions of the genome Genome Research ·Luciana Ferraris,Allan P. Stewart,Jinsuk Kang,Alec M. DeSimone,Matthew Gemberling,Dean Tantin,William G. Fairbrother	2011	29
17	High-throughput mapping of protein occupancy identifies functional elements without the restriction of a candidate factor approach Nucleic Acids Research ·Luciana Ferraris,Allan P. Stewart,Matthew Gemberling,Daniel C. Reid,M. J. Lapadula,William A. Thompson,William G. Fairbrother	2010	4
18	Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence RNA ·Daniel C. Reid,Brian L. Chang,Samuel Gunderson,Lauren Alpert,William A. Thompson,William G. Fairbrother	2009	39
19	Repressing the neuron within BioEssays ·William G. Fairbrother,Diane Lipscombe	2007	16
20	RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons Nucleic Acids Research ·William G. Fairbrother,G Yeo,Ru‐Fang Yeh,Pavel Goldstein,Matthew Mawson,Phillip A. Sharp,C. B. Burge	2004	224

About William G. Fairbrother

William G. Fairbrother is a scholar working on Molecular Biology, Cancer Research and Genetics, having authored 48 papers that have together received 3.0k indexed citations. Recurring topics across this work include RNA Research and Splicing (35 papers), RNA modifications and cancer (29 papers), RNA and protein synthesis mechanisms (23 papers), Cancer-related molecular mechanisms research (4 papers), Genomics and Chromatin Dynamics (4 papers), Neurogenetic and Muscular Disorders Research (3 papers), CRISPR and Genetic Engineering (3 papers) and SARS-CoV-2 and COVID-19 Research (2 papers). The work is most often cited by research in Molecular Biology (2.5k citations), Cancer Research (342 citations) and Genetics (197 citations). William G. Fairbrother has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Phillip A. Sharp, Christopher B. Burge, Ru‐Fang Yeh, Kamil J. Cygan, Kian‐Huat Lim, Allison J. Taggart, Lawrence A. Chasin, Benjamin J. Raphael, Dirk Holste and Rachel Soemedi. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

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