William C. Gause

15.2k citations

133 papers · 12.1k indexed · 3 hit papers · h-index 60

Impact in

Parasitology top 0.05%
- Parasites and Host Interactions
Immunology top 0.2%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- IL-33, ST2, and ILC Pathways
- Immunotherapy and Immune Responses

Papers in

Parasitology 52
- Parasites and Host Interactions 48
Immunology 59
- Immune Cell Function and Interaction 21
- T-cell and B-cell Immunology 21
- IL-33, ST2, and ILC Pathways 13
- Immunotherapy and Immune Responses 12

Co-authors: Joseph F. Urban Fred D. Finkelman Robert M. Anthony Kathleen B. Madden Suzanne C. Morris Thomas A. Wynn Zhugong Liu Terez Shea‐Donohue
Journals: The Journal of Immunology (49 papers)The Journal of Experimental Medicine (5 papers)Trends in Immunology (5 papers)Nature reviews. Immunology (3 papers)Infection and Immunity (3 papers)
Partner nations: United States Netherlands United Kingdom

In The Last Decade

William C. Gause

132 papers receiving 11.9k citations

Hit Papers

align trajectories log scale

Helminth infection promotes colonization resistance via type 2 immunity 2016 · 300 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2016 Science
2007 Nature reviews. Immunology
1997 Annual Review of Immunology

Peers

Countries citing papers authored by William C. Gause

Since Specialization

Citations

This map shows the geographic impact of William C. Gause's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William C. Gause with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William C. Gause more than expected).

Fields of papers citing papers by William C. Gause

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William C. Gause. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William C. Gause. The network helps show where William C. Gause may publish in the future.

Co-authorship network

The 25 scholars most cited alongside William C. Gause, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William C. Gause Line = papers co-authored together William C. Gause links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Helminth protein enhances wound healing by inhibiting fibrosis and promoting tissue regeneration Life Science Alliance ·Strong Hinman, Fei Chen, Pankaj Kumar Mishra, Danielle J. Smyth, Wenhui Wu, Alexander Lemenze, Yosuke Kumamoto, Rick M. Maizels, William C. Gause	2024	2
2	The Impact of Helminth Coinfection on Innate and Adaptive Immune Resistance and Disease Tolerance during Toxoplasmosis The Journal of Immunology ·fatima Bensaha, Darine W. El-Naccache, Хисамутдинов Амир Александрович, Yanlin Zhao, Chris Keniston, Zhihui Han, William C. Gause, George Yap	2022	6
3	Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity Cancer Research ·Viralkumar Davra, Sushil Kumar, Ke Geng, David Calianese, William T. De Haney, Rachel Rapaport, Canan Kasikara, XU Hang-xia, Yun‐Juan Chang, Michael Wichroski, Chan Gao, Mariana S. De Lorenzo, Sergei V. Kotenko, Tessa Bergsbaken, Pankaj Kumar Mishra, William C. Gause, Michael Quigley, Thomas Spires, Raymond B. Birge	2020	61
4	Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages PLoS Pathogens ·Julia Esser‐von Bieren, Ilaria Mosconi, Romain Guiet, Rodolfo Moreno-Alvarado, Akira Yamamura, E. Kučcrová, William C. Gause, Arne Seitz, J. Sjef Verbeek, Nicola Harris	2013	88
5	RELM-beta is required for optimal development of theTh2 cytokine response to the intestinal parasite Heligmosomoides polygyrus (37.53) The Journal of Immunology ·Nirav Patel, Pankaj Kumar Mishra, William C. Gause	2010	0
6	Nippostrongylus brasiliensis infection modulates Mycobacterium tuberculosis induced Th1 response (43.45) The Journal of Immunology ·Kamlesh Bhatt, Zhugong Liu, William C. Gause, Padmini Salgame	2007	2
7	The Role of B Cells in the Development of CD4 Effector T Cells during a Polarized Th2 Immune Response The Journal of Immunology ·Qian Liu, Zhugong Liu, Cristina Rozo, Hossein A. Hamed, Farhang Alem, Joseph F. Urban, William C. Gause	2007	57
8	Immune Regulation of Protease-Activated Receptor-1 Expression in Murine Small Intestine during Nippostrongylus brasiliensis Infection The Journal of Immunology ·Aiping Zhao, M. Morimoto, Harry Dawson, 廖禹林, Kathleen B. Madden, William C. Gause, Booki Min, Fred D. Finkelman, Joseph F. Urban, Terez Shea‐Donohue	2005	35
9	Adenosine Augments IL-10 Production by Macrophages through an A2B Receptor-Mediated Posttranscriptional Mechanism The Journal of Immunology ·Zoltán Németh, Carol S. Lutz, Balázs Csóka, Edwin A. Deitch, S. Joseph Leibovich, William C. Gause, Masahide Tone, Pál Pacher, E. Sylvester Vizi, György Haskó	2005	240
10	IL-2 and Autocrine IL-4 Drive the In Vivo Development of Antigen-Specific Th2 T Cells Elicited by Nematode Parasites The Journal of Immunology ·Zhugong Liu, Qian Liu, Hossein A. Hamed, Robert M. Anthony, Anthony Foster, Fred D. Finkelman, Joseph F. Urban, William C. Gause	2005	40
11	Peripheral CD4 T Cells Rapidly Accumulate at the Host:Parasite Interface during an Inflammatory Th2 Memory Response The Journal of Immunology ·M. Morimoto, Masahiro Morimoto, Jeannette M. Whitmire, Shiyun Xiao, Robert M. Anthony, M Rerat, Robert A. Star, Joseph F. Urban, William C. Gause	2004	68
12	Dependence of IL-4, IL-13, and Nematode-Induced Alterations in Murine Small Intestinal Smooth Muscle Contractility on Stat6 and Enteric Nerves The Journal of Immunology ·Aiping Zhao, Joseph McDermott, Joseph F. Urban, William C. Gause, Kathleen B. Madden, Karla Au Yeung, Suzanne C. Morris, Fred D. Finkelman, Terez Shea‐Donohue	2003	162
13	In Vivo CD86 Blockade Inhibits CD4+ T Cell Activation, Whereas CD80 Blockade Potentiates CD8+ T Cell Activation and CTL Effector Function The Journal of Immunology ·宏久須藤, Phuong Nguyen, Robert Peach, William C. Gause, Charles S. Via	2002	62
14	Memory Th2 Effector Cells Can Develop in the Absence of B7-1/B7-2, CD28 Interactions, and Effector Th Cells After Priming with an Intestinal Nematode Parasite The Journal of Immunology ·Melinda J. Ekkens, Zhugong Liu, Qian Liu, Anthony Foster, Jeannette M. Whitmire, John Pesce, Arlene H. Sharpe, Joseph F. Urban, William C. Gause	2002	26
15	Role of STAT6 and Mast Cells in IL-4- and IL-13-Induced Alterations in Murine Intestinal Epithelial Cell Function The Journal of Immunology ·Kathleen B. Madden, Lucia Whitman, Carolyn Sullivan, William C. Gause, Joseph F. Urban, Ildy M. Katona, Fred D. Finkelman, Terez Shea‐Donohue	2002	139
16	IL-13-Mediated Worm Expulsion Is B7 Independent and IFN-γ Sensitive The Journal of Immunology ·Joseph F. Urban, Hui Fang, Qian Liu, Melinda J. Ekkens, Shen-Jue Chen, Diep Ngoc Nguyen, Clemens Alt, Debra D. Donaldson, Clémence Couquelet, Robert Peach, Suzanne C. Morris, Fred D. Finkelman, Lisa Schopf, William C. Gause	2000	43
17	B7 Requirements for Primary and Secondary Protein- and Polysaccharide-Specific Ig Isotype Responses to Streptococcus pneumoniae The Journal of Immunology ·Zheng-Qi Wu, Abdul Qayyum Khan, Yi Shen, Jenniver Limpert, Robert Peach, Andrew Lees, James J. Mond, William C. Gause, Clifford M. Snapper	2000	37
18	IL-4 Suppression of In Vivo T Cell Activation and Antibody Production The Journal of Immunology ·Suzanne C. Morris, William C. Gause, Fred D. Finkelman	2000	24
19	Development of Murine Allergic Asthma Is Dependent Upon B7-2 Costimulation The Journal of Immunology ·Andrea Keane‐Myers, William C. Gause, Fred D. Finkelman, Andreas Nievergelt, Marsha Wills‐Karp	1998	94
20	CD40-mediated stimulation contributes to lymphocyte proliferation, antibody production, eosinophilia, and mastocytosis during an in vivo type 2 response, but is not required for T cell IL-4 production The Journal of Immunology ·Ping Lü, Joseph F. Urban, Xingyi Zhou, Curtis Meyers, Kelley S. Madden, Mark A. Moorman, Hung Q. Nguyen, Suzanne C. Morris, Fred D. Finkelman, William C. Gause	1996	35

About William C. Gause

William C. Gause is a scholar working on Parasitology, Immunology, Small Animals, Physiology and Infectious Diseases, having authored 133 papers that have together received 12.1k indexed citations. Recurring topics across this work include Parasites and Host Interactions (48 papers), Immune Cell Function and Interaction (21 papers), T-cell and B-cell Immunology (21 papers), Helminth infection and control (17 papers), Parasitic Diseases Research and Treatment (16 papers), IL-33, ST2, and ILC Pathways (13 papers), Parasite Biology and Host Interactions (13 papers) and Immunotherapy and Immune Responses (12 papers). The work is most often cited by research in Parasitology (3.8k citations), Immunology (5.8k citations), Small Animals (1.5k citations), Infectious Diseases (1.8k citations) and Immunology and Allergy (585 citations). William C. Gause has collaborated with scholars based in United States, Netherlands and United Kingdom. Frequent co-authors include Joseph F. Urban, Fred D. Finkelman, Robert M. Anthony, Kathleen B. Madden, Suzanne C. Morris, Thomas A. Wynn, Zhugong Liu, Terez Shea‐Donohue, Laura I. Rutitzky and Miguel J. Stadecker. Their work appears in journals such as The Journal of Immunology, The Journal of Experimental Medicine, Trends in Immunology, Nature reviews. Immunology and Infection and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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