William A. Frazier

16.1k total citations · 4 hit papers
153 papers, 13.3k citations indexed

About

William A. Frazier is a scholar working on Molecular Biology, Cancer Research and Immunology. According to data from OpenAlex, William A. Frazier has authored 153 papers receiving a total of 13.3k indexed citations (citations by other indexed papers that have themselves been cited), including 76 papers in Molecular Biology, 34 papers in Cancer Research and 32 papers in Immunology. Recurrent topics in William A. Frazier's work include Angiogenesis and VEGF in Cancer (44 papers), Protease and Inhibitor Mechanisms (30 papers) and Phagocytosis and Immune Regulation (26 papers). William A. Frazier is often cited by papers focused on Angiogenesis and VEGF in Cancer (44 papers), Protease and Inhibitor Mechanisms (30 papers) and Phagocytosis and Immune Regulation (26 papers). William A. Frazier collaborates with scholars based in United States, France and Sweden. William A. Frazier's co-authors include David D. Roberts, Nader Sheibani, Ralph Bradshaw, Vishva M. Dixit, Frederik P. Lindberg, Noël Bouck, Ai-Guo Gao, Jeff S. Isenberg, Samuel A. Santoro and Linda F. Boyd and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

William A. Frazier

152 papers receiving 12.8k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

2009 1.2k citations William A. Frazier et al. profile →
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 854 citations William A. Frazier et al. profile →
CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

2015 611 citations William A. Frazier et al. profile →
CD36 Mediates the In Vitro Inhibitory Effects of Thrombospondin-1 on Endothelial Cells

1997 547 citations Roy L. Silverstein, William A. Frazier et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
William A. Frazier	6.8k	4.3k	2.4k	1.9k	1.8k	153	13.3k
Tucker Collins	6.0k 0.9×	4.0k 0.9×	2.5k 1.0×	2.0k 1.0×	1.2k 0.7×	86	12.4k
Daniel F. Bowen‐Pope	6.9k 1.0×	2.0k 0.5×	1.5k 0.6×	1.5k 0.8×	1.0k 0.6×	105	13.1k
Steven L. Gonias	5.0k 0.7×	1.7k 0.4×	3.6k 1.5×	1.3k 0.7×	1.1k 0.6×	223	11.0k
Joanne E. Murphy-Ullrich	5.8k 0.8×	2.2k 0.5×	1.8k 0.8×	1.5k 0.8×	938 0.5×	111	11.3k
Andrius Kazlauskas	9.8k 1.4×	2.3k 0.6×	1.3k 0.5×	1.1k 0.6×	840 0.5×	188	15.1k
Thomas F. Deuel	8.1k 1.2×	1.7k 0.4×	1.7k 0.7×	1.5k 0.8×	674 0.4×	170	15.8k
Lewis T. Williams	15.2k 2.2×	4.6k 1.1×	1.8k 0.8×	1.5k 0.8×	1.1k 0.6×	114	22.0k
Toru Nakano	12.9k 1.9×	4.6k 1.1×	1.8k 0.8×	697 0.4×	1.3k 0.7×	208	18.9k
Carl Blobel	8.0k 1.2×	2.8k 0.7×	2.7k 1.1×	4.4k 2.4×	1.2k 0.7×	148	16.2k
M. Luisa Iruela‐Arispe	12.5k 1.8×	2.8k 0.6×	5.0k 2.1×	2.2k 1.2×	888 0.5×	202	21.4k

Countries citing papers authored by William A. Frazier

Since Specialization

Citations

This map shows the geographic impact of William A. Frazier's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William A. Frazier with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William A. Frazier more than expected).

Fields of papers citing papers by William A. Frazier

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William A. Frazier. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William A. Frazier. The network helps show where William A. Frazier may publish in the future.

Co-authorship network of co-authors of William A. Frazier

This figure shows the co-authorship network connecting the top 25 collaborators of William A. Frazier. A scholar is included among the top collaborators of William A. Frazier based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William A. Frazier. William A. Frazier is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Donaldson, Ashleigh C., Maria Chiara Monaco, Emily Stack, et al.. (2025). Broad-spectrum antiviral brincidofovir inhibits Epstein-Barr virus and related gammaherpesvirus in human and nonhuman primate cells. Journal of Clinical Investigation. 136(2).

Puro, Robyn J., Myriam N. Bouchlaka, Ronald R. Hiebsch, et al.. (2019). Development of AO-176, a Next-Generation Humanized Anti-CD47 Antibody with Novel Anticancer Properties and Negligible Red Blood Cell Binding. Molecular Cancer Therapeutics. 19(3). 835–846. 67 indexed citations

Azcutia, Verónica, Matthew Routledge, Marcie R. Williams, et al.. (2013). CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions. Molecular Biology of the Cell. 24(21). 3358–3368. 57 indexed citations

Uluçkan, Özge, Hongju Deng, Wei Zou, et al.. (2009). CD47 Regulates Bone Mass and Tumor Metastasis to Bone. Cancer Research. 69(7). 3196–3204. 67 indexed citations

Isenberg, Jeff S., Martin J. Romeo, Margaret E. Rick, et al.. (2007). Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood. 111(2). 613–623. 164 indexed citations

Manna, Partha Pratim, et al.. (2006). Deficit of CD47 Results in a Defect of Marginal Zone Dendritic Cells, Blunted Immune Response to Particulate Antigen and Impairment of Skin Dendritic Cell Migration. The Journal of Immunology. 176(10). 5772–5778. 55 indexed citations

Manna, Partha Pratim & William A. Frazier. (2003). The Mechanism of CD47-Dependent Killing of T Cells: Heterotrimeric Gi-Dependent Inhibition of Protein Kinase A. The Journal of Immunology. 170(7). 3544–3553. 75 indexed citations

Podrez, Eugene A., Maria Febbraio, Nader Sheibani, et al.. (2000). Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. Journal of Clinical Investigation. 105(8). 1095–1108. 354 indexed citations

Wang, Xueqing & William A. Frazier. (1998). The Thrombospondin Receptor CD47 (IAP) Modulates and Associates with α2β1 Integrin in Vascular Smooth Muscle Cells. Molecular Biology of the Cell. 9(4). 865–874. 145 indexed citations

10.

Sheibani, Nader & William A. Frazier. (1998). Down-Regulation of Platelet Endothelial Cell Adhesion Molecule-1 Results in Thrombospondin-1 Expression and Concerted Regulation of Endothelial Cell Phenotype. Molecular Biology of the Cell. 9(4). 701–713. 43 indexed citations

11.

Sheibani, Nader, Peter J. Newman, & William A. Frazier. (1997). Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis.. Molecular Biology of the Cell. 8(7). 1329–1341. 75 indexed citations

12.

Frazier, William A.. (1992). Structure and Function of Thrombospondins.. Trends in Glycoscience and Glycotechnology. 4(16). 152–158. 1 indexed citations

13.

Santoro, Samuel A. & William A. Frazier. (1987). [24] Isolation and characterization of thrombospondin. Methods in enzymology on CD-ROM/Methods in enzymology. 144. 438–446. 24 indexed citations

14.

Baggett, J. R., et al.. (1984). ‘Oregon Trail’ Green Bean. HortScience. 19(1). 134–134. 1 indexed citations

15.

Baggett, J. R. & William A. Frazier. (1982). Oregon 11 Early Parthenocarpic Tomato Breeding Line1. HortScience. 17(6). 984–985. 2 indexed citations

16.

Baggett, J. R. & William A. Frazier. (1978). ‘Oregon Cherry’ Tomato1. HortScience. 13(5). 598–598. 3 indexed citations

17.

Baggett, J. R. & William A. Frazier. (1978). Oregon T5-4 Parthenocarpic Tomato Line1. HortScience. 13(5). 599–599. 8 indexed citations

18.

Frazier, William A., et al.. (1974). The Influence of Processing and Maturity on Volatile Components in Bush Snap Beans, Phaseolus vulgaris L.1. Journal of the American Society for Horticultural Science. 99(6). 493–497. 8 indexed citations

19.

Frazier, William A.. (1969). Horticulture’s Issues in Education, Science, Communication, Philosophy, Politics, and Human Welfare. HortScience. 4(4). 276–284. 1 indexed citations

20.

Frazier, William A., et al.. (1960). Correlation between certain seedling and mature plant characters in rhubarb.. 76. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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