William A. Eaton

24.2k total citations · 8 hit papers
167 papers, 19.6k citations indexed

About

William A. Eaton is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, William A. Eaton has authored 167 papers receiving a total of 19.6k indexed citations (citations by other indexed papers that have themselves been cited), including 111 papers in Molecular Biology, 77 papers in Cell Biology and 43 papers in Physiology. Recurrent topics in William A. Eaton's work include Protein Structure and Dynamics (76 papers), Hemoglobin structure and function (74 papers) and Erythrocyte Function and Pathophysiology (40 papers). William A. Eaton is often cited by papers focused on Protein Structure and Dynamics (76 papers), Hemoglobin structure and function (74 papers) and Erythrocyte Function and Pathophysiology (40 papers). William A. Eaton collaborates with scholars based in United States, Italy and Germany. William A. Eaton's co-authors include James Hofrichter, Eric R. Henry, Benjamin Schuler, Víctor Muñoz, Jan Kubelka, Hoi Sung Chung, Peggy A. Thompson, Everett A. Lipman, Frank A. Ferrone and Stephen J. Hagen and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

William A. Eaton

165 papers receiving 19.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Folding dynamics and mechanism of β-hairpin formation

1997 809 citations Peggy A. Thompson, James Hofrichter et al. profile →
Probing the free-energy surface for protein folding with single-molecule fluorescence spectroscopy

2002 746 citations Benjamin Schuler, William A. Eaton et al. profile →
The protein folding ‘speed limit’

2004 690 citations Jan Kubelka, James Hofrichter et al. profile →
Protein folding studied by single-molecule FRET

2008 544 citations Benjamin Schuler, William A. Eaton profile →
A simple model for calculating the kinetics of protein folding from three-dimensional structures

1999 531 citations William A. Eaton et al. Proceedings of the National Academy of Sciences profile →
Native contacts determine protein folding mechanisms in atomistic simulations

2013 446 citations Robert B. Best, Gerhard Hummer et al. Proceedings of the National Academy of Sciences profile →
Kinetics of sickle hemoglobin polymerization

1985 418 citations James Hofrichter, William A. Eaton et al. Journal of Molecular Biology profile →
Kinetics and Mechanism of Deoxyhemoglobin S Gelation: A New Approach to Understanding Sickle Cell Disease

1974 416 citations James Hofrichter, William A. Eaton et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by William A. Eaton

Since Specialization

Citations

This map shows the geographic impact of William A. Eaton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William A. Eaton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William A. Eaton more than expected).

Fields of papers citing papers by William A. Eaton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William A. Eaton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William A. Eaton. The network helps show where William A. Eaton may publish in the future.

Co-authorship network of co-authors of William A. Eaton

This figure shows the co-authorship network connecting the top 25 collaborators of William A. Eaton. A scholar is included among the top collaborators of William A. Eaton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William A. Eaton. William A. Eaton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Long-term mitapivat treatment is safe and efficacious in patients with sickle cell disease 2025 ·PubMed ·Anna Conrey, (unknown), Ingrid Frey, (unknown), (unknown), Julia Xu, (unknown), Kang Le, (unknown), Quan Li, Emily B. Dunkelberger, Troy Cellmer, Amber M. Yates, Megan Wind‐Rotolo, (unknown), Neal Jeffries, William A. Eaton, Swee Lay Thein	0
2	Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease 2024 ·Haematologica ·Angelo D’Alessandro, Kang Le, (unknown), Quan Li, Emily B. Dunkelberger, Troy Cellmer, Andrew J. Worth, (unknown), (unknown), (unknown), Monika Dzieciątkowska, Daniel Stephenson, William A. Eaton, Swee Lay Thein	5
3	MWC allosteric model explains unusual hemoglobin-oxygen binding curves from sickle cell drug binding 2021 ·Biophysical Journal ·Eric R. Henry, (unknown), (unknown), Belhu Metaferia, John M. Louis, William A. Eaton	9
4	Impact of Conformational Substates and Energy Landscapes on Understanding Hemoglobin Kinetics and Function 2021 ·Journal of Biological Physics ·William A. Eaton	3
5	Physics of virus transmission by speaking droplets 2020 ·Proceedings of the National Academy of Sciences ·Roland R. Netz, William A. Eaton	42
6	Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models 2015 ·Biophysical Journal ·Eric R. Henry, Andrea Mozzarelli, Cristiano Viappiani, Stefania Abbruzzetti, Stefano Bettati, Luca Ronda, Stefano Bruno, William A. Eaton	33
7	Single Molecule FRET Studies of DNA Hairpin Folding 2014 ·Biophysical Journal ·(unknown), Hoi Sung Chung, William A. Eaton, John M. Louis	1
8	Native contacts determine protein folding mechanisms in atomistic simulations breakdown → 2013 ·Proceedings of the National Academy of Sciences ·Robert B. Best, Gerhard Hummer, William A. Eaton	446
9	Single-Molecule FRET Shows Folding Transition Path Time for All-Alpha Protein Slowed by Internal Friction 2013 ·Biophysical Journal ·Hoi Sung Chung, John M. Louis, William A. Eaton	1
10	Photon-By-Photon Analysis of Single Molecule Fluorescence Trajectories Determines an Upper Bound for the Transition Path Time in Protein Folding 2011 ·Biophysical Journal ·Hoi Sung Chung, Irina V. Gopich, Kevin McHale, John M. Louis, William A. Eaton	0
11	Distinguishing between Protein Dynamics and Dye Photophysics in Single-Molecule FRET Experiments 2010 ·Biophysical Journal ·Hoi Sung Chung, John M. Louis, William A. Eaton	53
12	Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories 2009 ·Proceedings of the National Academy of Sciences ·Hoi Sung Chung, John M. Louis, William A. Eaton	236
13	New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels 2004 ·Proceedings of the National Academy of Sciences ·Cristiano Viappiani, Stefano Bettati, Stefano Bruno, Luca Ronda, Stefania Abbruzzetti, Andrea Mozzarelli, William A. Eaton	96
14	Kinetics of Intramolecular Contact Formation in a Denatured Protein 2003 ·Journal of Molecular Biology ·Marco Buscaglia, Benjamin Schuler, Lisa J. Lapidus, William A. Eaton, James Hofrichter	51
15	Experimental Tests of Villin Subdomain Folding Simulations 2003 ·Journal of Molecular Biology ·Jan Kubelka, William A. Eaton, James Hofrichter	205
16	Measuring the rate of intramolecular contact formation in polypeptides 2000 ·Proceedings of the National Academy of Sciences ·Lisa J. Lapidus, William A. Eaton, James Hofrichter	364
17	Fast events in protein folding 1996 ·Structure ·William A. Eaton, Peggy A. Thompson, (unknown), (unknown), James Hofrichter	104
18	Oxygen binding by single crystals of hemoglobin: The problem of cooperativity and inequivalence of alpha and beta subunits 1996 ·Proteins Structure Function and Bioinformatics ·Stefano Bettati, Andrea Mozzarelli, Gian Luigi Rossi, Antonio Tsuneshige, Takashi Yonetani, William A. Eaton, Eric R. Henry	24
19	Current Perspectives on the Kinetics of Hemoglobin S Gelation 1989 ·Annals of the New York Academy of Sciences ·Pier Luigi San Biagio, James Hofrichter, Andrea Mozzarelli, Eric R. Henry, William A. Eaton	8
20	[16] Polarized absorption and linear dichroism spectroscopy of hemoglobin 1981 ·Methods in enzymology on CD-ROM/Methods in enzymology ·William A. Eaton, James Hofrichter	180

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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