Seema Irani

487 total citations
21 papers, 331 citations indexed

About

Seema Irani is a scholar working on Molecular Biology, Oncology and Pharmacology. According to data from OpenAlex, Seema Irani has authored 21 papers receiving a total of 331 indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 3 papers in Oncology and 3 papers in Pharmacology. Recurrent topics in Seema Irani's work include RNA Research and Splicing (10 papers), Genomics and Chromatin Dynamics (10 papers) and RNA modifications and cancer (5 papers). Seema Irani is often cited by papers focused on RNA Research and Splicing (10 papers), Genomics and Chromatin Dynamics (10 papers) and RNA modifications and cancer (5 papers). Seema Irani collaborates with scholars based in United States, China and Bulgaria. Seema Irani's co-authors include Yan Zhang, Joshua E. Mayfield, Wanjie Yang, Jennifer S. Brodbelt, Nathchar Naowarojna, Pinghua Liu, Wupeng Yan, Yasushi Ogasawara, Yeonjin Ko and Shao‐An Wang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Seema Irani

21 papers receiving 330 citations

Peers

Seema Irani

PHARM

ONCOL

SPECT

Chen‐Yu Lai Taiwan

Kristin K. Brown United States

Aman Iqbal United Kingdom

Andrew J. Robles United States

Mads H. Rønnest Denmark

Tai Wei Ly Taiwan

Luc Henry United Kingdom

Hilde van Hattum Netherlands

Jonathan D. Mortison United States

Peter Seden United Kingdom

Chen‐Yu Lai Taiwan

Seema Irani

230 ×1.0

95 ×1.8

PHARM

45 ×1.1

21 ×0.7

ONCOL

74 ×2.7

SPECT

Citations per year, relative to Seema Irani Seema Irani (= 1×) peers Chen‐Yu Lai

Countries citing papers authored by Seema Irani

Since Specialization

Citations

This map shows the geographic impact of Seema Irani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seema Irani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seema Irani more than expected).

Fields of papers citing papers by Seema Irani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seema Irani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seema Irani. The network helps show where Seema Irani may publish in the future.

Co-authorship network of co-authors of Seema Irani

This figure shows the co-authorship network connecting the top 25 collaborators of Seema Irani. A scholar is included among the top collaborators of Seema Irani based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Seema Irani. Seema Irani is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Panina, Svetlana, et al.. (2024). Thr ⁴ phosphorylation on RNA Pol II occurs at early transcription regulating 3′-end processing. Science Advances. 10(36). eadq0350–eadq0350. 3 indexed citations

Irani, Seema, Qing Li, Weiyi Toy, et al.. (2023). Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation. Journal of Clinical Investigation. 134(1). 9 indexed citations

Lü, Bin, Ruopeng Feng, Yu Yao, et al.. (2022). SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia. Cell Reports. 38(2). 110233–110233. 4 indexed citations

Zhou, Ruyuan, Qirou Wu, Seema Irani, et al.. (2021). The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration. PLoS Biology. 19(2). e3001122–e3001122. 19 indexed citations

Yang, Wanjie, et al.. (2021). Simplicity is the Ultimate Sophistication—Crosstalk of Post-translational Modifications on the RNA Polymerase II. Journal of Molecular Biology. 433(14). 166912–166912. 18 indexed citations

Yang, Wanjie, Srihari Konduri, Jiajun Dong, et al.. (2021). Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells. Journal of Medicinal Chemistry. 65(1). 507–519. 5 indexed citations

Mayfield, Joshua E., Seema Irani, & Yan Zhang. (2020). Electrophoretic Mobility Shift Assay of in vitro Phosphorylated RNA Polymerase II Carboxyl-terminal Domain Substrates. BIO-PROTOCOL. 10(12). e3648–e3648. 2 indexed citations

Irani, Seema, et al.. (2020). Structural Motifs for CTD Kinase Specificity on RNA Polymerase II during Eukaryotic Transcription. ACS Chemical Biology. 15(8). 2259–2272. 9 indexed citations

Lu, Weicheng, Achinto Saha, Wupeng Yan, et al.. (2020). Enzyme-mediated depletion of serum l -Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proceedings of the National Academy of Sciences. 117(23). 13000–13011. 38 indexed citations

10.

Naowarojna, Nathchar, Seema Irani, Weiyao Hu, et al.. (2019). Crystal Structure of the Ergothioneine Sulfoxide Synthase from Candidatus Chloracidobacterium thermophilum and Structure-Guided Engineering To Modulate Its Substrate Selectivity. ACS Catalysis. 9(8). 6955–6961. 23 indexed citations

11.

Irani, Seema, et al.. (2019). Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription. Journal of Biological Chemistry. 294(21). 8592–8605. 12 indexed citations

12.

Irani, Seema, et al.. (2019). Mapping RNAPII CTD Phosphorylation Reveals That the Identity and Modification of Seventh Heptad Residues Direct Tyr1 Phosphorylation. ACS Chemical Biology. 14(10). 2264–2275. 6 indexed citations

13.

Mayfield, Joshua E., Seema Irani, Zhao Zhang, et al.. (2019). Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb. eLife. 8. 29 indexed citations

14.

Wang, Shao‐An, Yeonjin Ko, Jia Zeng, et al.. (2019). Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis. Journal of the American Chemical Society. 141(15). 6127–6131. 46 indexed citations

15.

Kumar, Mukesh, et al.. (2019). Modification of Ser ₇ of the RNA Polymerase II C‐terminal domain (CTD) regulates CTD phosphorylation patterns and transcription. The FASEB Journal. 33(S1). 1 indexed citations

16.

Irani, Seema, Nathchar Naowarojna, Yang Tang, et al.. (2018). Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism. Cell chemical biology. 25(5). 519–529.e4. 39 indexed citations

17.

Mayfield, Joshua E., et al.. (2018). Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). Journal of Biological Chemistry. 293(43). 16851–16861. 16 indexed citations

18.

Irani, Seema, et al.. (2017). Examining the Mechanism of Egt2 in Ergothioneine Biosynthesis. The FASEB Journal. 31(S1). 2 indexed citations

19.

Mayfield, Joshua E., Michelle Robinson, Victoria C. Cotham, et al.. (2016). Mapping the Phosphorylation Pattern of Drosophila melanogaster RNA Polymerase II Carboxyl-Terminal Domain Using Ultraviolet Photodissociation Mass Spectrometry. ACS Chemical Biology. 12(1). 153–162. 23 indexed citations

20.

Irani, Seema, S.D. Yogesha, Joshua E. Mayfield, et al.. (2016). Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase. Science Signaling. 9(417). ra24–ra24. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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