W. J. Pledger

9.7k citations

114 papers · 7.9k indexed · 3 hit papers · h-index 42

Impact in

Oncology top 1%
- Cancer-related Molecular Pathways
- Cytokine Signaling Pathways and Interactions
Cell Biology top 0.5%

Papers in

Oncology 56
- Cancer-related Molecular Pathways 37
- Colorectal Cancer Treatments and Studies 8
Cancer Research 18
- Cancer, Hypoxia, and Metabolism 9

Co-authors: Charles D. Scher Charles D. Stiles Harry N. Antoniades Walker Wharton Judson J. Van Wyk Nancy Olashaw Giacomo Capone Richard Jove
Journals: Journal of Biological Chemistry (13 papers)Journal of Cellular Physiology (10 papers)Proceedings of the National Academy of Sciences (10 papers)Oncogene (9 papers)Molecular and Cellular Biology (6 papers)
Partner nations: United States France India

In The Last Decade

W. J. Pledger

114 papers receiving 7.6k citations

Hit Papers

align trajectories log scale

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis 2007 · 722 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2007 Nature Cell Biology
1979 Proceedings of the National Academy of Sciences
1977 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by W. J. Pledger

Since Specialization

Citations

This map shows the geographic impact of W. J. Pledger's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by W. J. Pledger with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites W. J. Pledger more than expected).

Fields of papers citing papers by W. J. Pledger

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by W. J. Pledger. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by W. J. Pledger. The network helps show where W. J. Pledger may publish in the future.

Co-authorship network

The 25 scholars most cited alongside W. J. Pledger, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with W. J. Pledger Line = papers co-authored together W. J. Pledger links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation Scientific Reports ·Thomas B. Davis, Mingli Yang, Michael J. Schell, Heiman Wang, Le Ma, W. J. Pledger, Timothy J. Yeatman	2018	21
2	Vitamin E δ-Tocotrienol Induces p27Kip1-Dependent Cell-Cycle Arrest in Pancreatic Cancer Cells via an E2F-1-Dependent Mechanism PLoS ONE ·Pamela J. Hodul, Yanbin Dong, Kazim Husain, José M. Pimiento, Jiandong Chen, Anying Zhang, R François, W. J. Pledger, Domenico Coppola, Saı̈d M. Sebti, Dung‐Tsa Chen, Mokenge P. Malafa	2013	36
3	Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor Cell Death and Disease ·Wei Fu, Padma Gurmet, L D Martins, María Mercedes Gallego Rodríguez, Marilyn M. Bui, Damon R. Reed, W. J. Pledger	2013	18
4	Proliferative status regulates HDAC11 mRNA abundance in nontransformed fibroblasts Cell Cycle ·Tapan Bagui, Padma Gurmet, Le Ma, W. J. Pledger	2013	15
5	The Establishment of the First Cancer Tissue Biobank at a Hispanic-Serving Institution: A National Cancer Institute–Funded Initiative between Moffitt Cancer Center in Florida and the Ponce School of Medicine and Health Sciences in Puerto Rico Biopreservation and Biobanking ·Idhaliz Flores, Teresita Muñoz-Antonia, Jaime Matta, M M Verma, David Fenstermacher, Yao Ping, Edward Seijo, H. Hehenberger, W. J. Pledger, Domenico Coppola	2011	7
6	Src kinase induces tumor formation in the c‐SRC C57BL/6 mouse International Journal of Cancer ·C. Leah B. Kline, Rosalind J. Jackson, Robert W. Engelman, W. J. Pledger, Timothy J. Yeatman, Rosalyn Irby	2008	13
7	Activation of p27Kip1 Expression by E2F1 Journal of Biological Chemistry ·Chuangui Wang, Xinghua Hou, Subhra Mohapatra, Yihong Ma, W. Douglas Cress, W. J. Pledger, Jiandong Chen	2005	67
8	p27 ^Kip1 and p21 ^Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes Molecular and Cellular Biology ·Tapan Bagui, Subhra Mohapatra, Eric B. Haura, W. J. Pledger	2003	74
9	Role of Gadd45α in the density-dependent G1 arrest induced by p27Kip1 Oncogene ·Xiaohong Zhang, V G Rima, Steven A. Enkemann, W. J. Pledger	2003	18
10	Density-dependent Growth Inhibition of Fibroblasts Ectopically Expressing p27^kip1 Molecular Biology of the Cell ·Xiaohong Zhang, Walker Wharton, Pieralessandro A. Fanti, Domenico Coppola, Rhonda Croxton, W. Douglas Cress, W. J. Pledger	2000	28
11	Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model Oncogene ·Jalila Adnane, Rosalind J. Jackson, Santo V. Nicosia, Alan Cantor, W. J. Pledger, Saı̈d Sebti	2000	79
12	Cyclin D3-associated Kinase Activity Is Regulated by p27^kip1in BALB/c 3T3 Cells Molecular Biology of the Cell ·Feng Dong, Deepak Agrawal, Tapan Bagui, W. J. Pledger	1998	33
13	Primary keratinocytes have an adhesion dependent S phase checkpoint that is absent in immortalized cell lines Oncogene ·Paul Hauser, Deepak Agrawal, W. J. Pledger	1998	11
14	Detergent solubility defines an alternative itinerary for a subpopulation of PDGF β receptors Journal of Cellular Physiology ·Steven Coats, W. J. Pledger, Midori Awazu, Thomas O. Daniel	1996	6
15	Selective Interferon-α/β Effects on Platelet-Derived Growth Factor-Stimulated Processes in Quiescent BALB/c-3T3 Fibroblasts Journal of Interferon Research ·Igor Tamm, Toyoko Kikuchi, David K. Kreutter, W. J. Pledger, Lawrence M. Pfeffer	1994	5
16	Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanisms. Molecular Biology of the Cell ·Jeffrey Winston, W. J. Pledger	1993	82
17	Induction of NF-kappa B-like activity by platelet-derived growth factor in mouse fibroblasts. Molecular Biology of the Cell ·Nancy Olashaw, Timothy F. Kowalik, Eng‐Shang Huang, W. J. Pledger	1992	33
18	Regulation of the transmodulated epidermal growth factor receptor by cholera toxin and the protein phosphatase inhibitor okadaic acid Journal of Cellular Biochemistry ·Jeffrey Winston, Nancy Olashaw, W. J. Pledger	1991	5
19	Growth factors in the tumorigenicity of a brain tumor cell line Pediatric Neurology ·Harry T. Whelan, W. J. Pledger, Robert J. Maciunas, Robert L. Galloway, William O. Whetsell, Harold L. Moses	1989	9
20	Association of platelet-derived growth factor-induced protein with nuclear material Nature ·Nancy Olashaw, W. J. Pledger	1983	34

About W. J. Pledger

W. J. Pledger is a scholar working on Oncology, Cancer Research, Molecular Biology, Cell Biology and Hematology, having authored 114 papers that have together received 7.9k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (37 papers), Ubiquitin and proteasome pathways (16 papers), Epigenetics and DNA Methylation (14 papers), Protein Kinase Regulation and GTPase Signaling (9 papers), Cancer, Hypoxia, and Metabolism (9 papers), Colorectal Cancer Treatments and Studies (8 papers), Fibroblast Growth Factor Research (8 papers) and Microtubule and mitosis dynamics (7 papers). The work is most often cited by research in Oncology (2.5k citations), Cell Biology (1.2k citations), Molecular Biology (5.0k citations), Cancer Research (1.0k citations) and Immunology and Allergy (377 citations). W. J. Pledger has collaborated with scholars based in United States, France and India. Frequent co-authors include Charles D. Scher, Charles D. Stiles, Harry N. Antoniades, Walker Wharton, Judson J. Van Wyk, Nancy Olashaw, Giacomo Capone, Richard Jove, Edward B. Leof and Jeffrey Winston. Their work appears in journals such as Journal of Biological Chemistry, Journal of Cellular Physiology, Proceedings of the National Academy of Sciences, Oncogene and Molecular and Cellular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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