C. Leah B. Kline

1.4k total citations
25 papers, 855 citations indexed

About

C. Leah B. Kline is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, C. Leah B. Kline has authored 25 papers receiving a total of 855 indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 12 papers in Oncology and 5 papers in Cancer Research. Recurrent topics in C. Leah B. Kline's work include Cell death mechanisms and regulation (8 papers), Cancer-related Molecular Pathways (4 papers) and Cancer, Stress, Anesthesia, and Immune Response (3 papers). C. Leah B. Kline is often cited by papers focused on Cell death mechanisms and regulation (8 papers), Cancer-related Molecular Pathways (4 papers) and Cancer, Stress, Anesthesia, and Immune Response (3 papers). C. Leah B. Kline collaborates with scholars based in United States, Ireland and United Kingdom. C. Leah B. Kline's co-authors include Wafik S. El‐Deiry, David T. Dicker, Joshua E. Allen, Varun V. Prabhu, A. Pieter J. van den Heuvel, Jessica Wagner, Rosalyn Irby, Marie D. Ralff, Lanlan Zhou and Amriti R. Lulla and has published in prestigious journals such as Journal of Clinical Investigation, Blood and PLoS ONE.

In The Last Decade

C. Leah B. Kline

23 papers receiving 848 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
C. Leah B. Kline United States	16	566	298	159	108	97	25	855
Robin Hallett Canada	18	527 0.9×	494 1.7×	259 1.6×	59 0.5×	136 1.4×	40	978
Steven T. Sizemore United States	17	584 1.0×	300 1.0×	186 1.2×	91 0.8×	76 0.8×	33	840
Arabel Vollmann‐Zwerenz Germany	15	459 0.8×	240 0.8×	231 1.5×	58 0.5×	131 1.4×	24	881
Marjon A. Smit Netherlands	11	608 1.1×	358 1.2×	180 1.1×	111 1.0×	117 1.2×	12	875
Sandeep Singh United States	15	642 1.1×	424 1.4×	255 1.6×	138 1.3×	77 0.8×	25	972
Trevor Price United States	9	340 0.6×	308 1.0×	140 0.9×	76 0.7×	140 1.4×	21	849
Jangsoon Lee United States	18	684 1.2×	434 1.5×	166 1.0×	187 1.7×	84 0.9×	40	1.1k
Hong Chang United States	13	463 0.8×	346 1.2×	118 0.7×	60 0.6×	41 0.4×	18	829
Julia M. Houthuijzen Netherlands	13	455 0.8×	507 1.7×	295 1.9×	53 0.5×	147 1.5×	19	1.0k
Hye Gyeong Park South Korea	12	531 0.9×	310 1.0×	361 2.3×	58 0.5×	85 0.9×	12	888

Countries citing papers authored by C. Leah B. Kline

Since Specialization

Citations

This map shows the geographic impact of C. Leah B. Kline's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Leah B. Kline with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Leah B. Kline more than expected).

Fields of papers citing papers by C. Leah B. Kline

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Leah B. Kline. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Leah B. Kline. The network helps show where C. Leah B. Kline may publish in the future.

Co-authorship network of co-authors of C. Leah B. Kline

This figure shows the co-authorship network connecting the top 25 collaborators of C. Leah B. Kline. A scholar is included among the top collaborators of C. Leah B. Kline based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with C. Leah B. Kline. C. Leah B. Kline is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Wagner, Jessica, C. Leah B. Kline, Lanlan Zhou, Vladimir Khazak, & Wafik S. El‐Deiry. (2018). Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms. Journal of Experimental & Clinical Cancer Research. 37(1). 11–11. 29 indexed citations

Wagner, Jessica, C. Leah B. Kline, Lanlan Zhou, et al.. (2018). Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment. Journal of Clinical Investigation. 128(6). 2325–2338. 55 indexed citations

Ralff, Marie D., C. Leah B. Kline, Jessica Wagner, et al.. (2017). ONC201 Demonstrates Antitumor Effects in Both Triple-Negative and Non–Triple-Negative Breast Cancers through TRAIL-Dependent and TRAIL-Independent Mechanisms. Molecular Cancer Therapeutics. 16(7). 1290–1298. 38 indexed citations

Prabhu, Varun V., Amriti R. Lulla, Neel S. Madhukar, et al.. (2017). Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors. PLoS ONE. 12(8). e0180541–e0180541. 30 indexed citations

Kline, C. Leah B., Marie D. Ralff, Amriti R. Lulla, et al.. (2017). Role of Dopamine Receptors in the Anticancer Activity of ONC201. Neoplasia. 20(1). 80–91. 94 indexed citations

Wagner, Jessica, C. Leah B. Kline, Lanlan Zhou, et al.. (2017). Abstract 124: Imipridone ONC201 promotes intra-tumoral accumulation of CD3+/NK+ cells that contribute to its anti-tumor efficacy. Cancer Research. 77(13_Supplement). 124–124.

Wagner, Jessica, C. Leah B. Kline, Marie D. Ralff, et al.. (2017). Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212. Cell Cycle. 16(19). 1790–1799. 56 indexed citations

Wagner, Jessica, et al.. (2016). Abstract 3000: Intra-tumoral accumulation of NK1.1/CD3+ cells and anti-metastasis effects of dose-intensified ONC201 in tumor-bearing mice. Cancer Research. 76(14_Supplement). 3000–3000. 2 indexed citations

Zhang, Shengliang, Lanlan Zhou, Bo Hong, et al.. (2015). Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53. Cancer Research. 75(18). 3842–3852. 92 indexed citations

10.

Wagner, Jessica, C. Leah B. Kline, Richard S. Pottorf, et al.. (2014). The angular structure of ONC201, a TRAIL pathway-inducing compound, determines its potent anti-cancer activity. Oncotarget. 5(24). 12728–12737. 35 indexed citations

11.

Prabhu, Varun V., Amriti R. Lulla, Jessica Wagner, et al.. (2014). Small Molecule ONC201/TIC10 Induces Caspase-Dependent Apoptosis in Acute Lymphoblastic Leukemia Cells Via Modulation of Bcl-2 and IAP Family Proteins. Blood. 124(21). 5237–5237.

12.

Kline, C. Leah B., Junjia Zhu, Harold A. Harvey, et al.. (2013). Personalized Dosing via Pharmacokinetic Monitoring of 5-Fluorouracil Might Reduce Toxicity in Early- or Late-Stage Colorectal Cancer Patients Treated With Infusional 5–Fluorouracil-Based Chemotherapy Regimens. Clinical Colorectal Cancer. 13(2). 119–126. 34 indexed citations

13.

Kline, C. Leah B. & Rosalyn Irby. (2011). The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU. APOPTOSIS. 16(12). 1285–1294. 12 indexed citations

14.

Kline, C. Leah B., et al.. (2011). Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients. Cancer Biology & Therapy. 12(7). 557–568. 18 indexed citations

15.

Pastor, Danielle M., Lisa S. Poritz, Thomas L. Olson, et al.. (2010). Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines.. PubMed. 3(1). 69–83. 28 indexed citations

16.

Wang, Bi‐Dar, C. Leah B. Kline, Danielle M. Pastor, et al.. (2010). Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network. Molecular Cancer. 9(1). 98–98. 44 indexed citations

17.

Kline, C. Leah B., Sriram S. Shanmugavelandy, Mark Kester, & Rosalyn Irby. (2009). Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU. Cancer Biology & Therapy. 8(19). 1831–1837. 27 indexed citations

18.

Kline, C. Leah B., Rosalind J. Jackson, Robert W. Engelman, et al.. (2008). Src kinase induces tumor formation in the c‐SRC C57BL/6 mouse. International Journal of Cancer. 122(12). 2665–2673. 13 indexed citations

19.

Kline, C. Leah B., Thomas L. Olson, & Rosalyn Irby. (2008). Src activity alters α3 integrin expression in colon tumor cells. Clinical & Experimental Metastasis. 26(2). 77–87. 8 indexed citations

20.

Kline, C. Leah B., et al.. (2005). Glucosamine-induced phosphorylation of the α-subunit of eukaryotic initiation factor 2 is mediated by the protein kinase R-like endoplasmic-reticulum associated kinase. The International Journal of Biochemistry & Cell Biology. 38(5-6). 1004–1014. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact