Valentina M. Factor

11.1k citations

109 papers · 8.7k indexed · 4 hit papers · h-index 55

Hepatology top 0.2%
- Liver physiology and pathology 33
Cancer Research top 0.5%
Oncology top 1%
- Cancer-related Molecular Pathways 23
Molecular Biology top 1%
- Epigenetics and DNA Methylation 11
- RNA modifications and cancer 11
- Cancer-related gene regulation 9
- TGF-β signaling in diseases 9
Pathology and Forensic Medicine top 2%
Epidemiology
- Liver Disease Diagnosis and Treatment 10
Surgery
- Pancreatic function and diabetes 9

Co-authors: Snorri S. Thorgeirsson Elizabeth A. Conner Jesper B. Andersen Diego F. Calvisi Cédric Coulouarn Sara Ladu Jens U. Marquardt S S Thorgeirsson
Cited by: Hepatology Cancer Research Oncology
Partner nations: United States South Korea Russia

In The Last Decade

Valentina M. Factor

108 papers receiving 8.6k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2011 Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors
2009 Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
2006 Ubiquitous Activation of Ras and Jak/Stat Pathways in Human HCC
2004 Hepatocyte growth factor/c-metsignaling pathway is required for efficient liver regeneration and repair

Peers

Countries citing papers authored by Valentina M. Factor

Since Specialization

Citations

This map shows the geographic impact of Valentina M. Factor's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Valentina M. Factor with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Valentina M. Factor more than expected).

Fields of papers citing papers by Valentina M. Factor

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Valentina M. Factor. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Valentina M. Factor. The network helps show where Valentina M. Factor may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Valentina M. Factor, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Valentina M. Factor Line = papers co-authored together Valentina M. Factor links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Topoisomerase III-beta protects from immune dysregulation and tumorigenesis Md Rasel Al Mahmud,Simone A. Baechler,Anjali Dhall,Sourav Saha,Hongliang Zhang,Laura Bassel,Shuling Zhang,Min-Jung Lee,N Sato,Shraddha Rastogi,Suresh Kumar,Muhammad S. Alam,Liton Kumar Saha,Beverly A. Mock,Valentina M. Factor,Yves Pommier	2025	0
2	Human chemically-derived hepatic progenitors (hCdHs) as a source of liver organoid generation: Application in regenerative medicine, disease modeling, and toxicology testing Soraya Salas‐Silva,Yohan Kim,Tae Hun Kim,Myounghoi Kim,Daekwan Seo,Jeonghoon Choi,Valentina M. Factor,Haeng Ran Seo,Yeonhwa Song,Gyu Sung Choi,Yun Kyung Jung,Kungsik Kim,Kyeong Geun Lee,Jaemin Jeong,Ji Hyun Shin,Dongho Choi	2023	16
3	Transplantation of patient‐specific bile duct bioengineered with chemically reprogrammed and microtopographically differentiated cells Elina Maria Buisson,Suk‐Hee Park,Myounghoi Kim,Kyojin Kang,Sangtae Yoon,Ji Eun Lee,Young Won Kim,Nak Kyu Lee,Mi Ae Jeong,Bo‐Kyeong Kang,Seung Bum Lee,Valentina M. Factor,Daekwan Seo,Hyunsung Kim,Jaemin Jeong,(unknown),(unknown),Dongho Choi	2021	10
4	Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers Dan Høgdall,Colm J. O’Rourke,Christian Dehlendorff,Ole Larsen,Lars Henrik Jensen,Astrid Z. Johansen,Hien Dang,Valentina M. Factor,Mie Grunnet,Morten Mau‐Sørensen,Douglas V.N.P. Oliveira,Dorte Linnemann,Mogens K. Boisen,Xin Wei Wang,Julia S. Johansen,Jesper B. Andersen	2020	21
5	Integrated Genomic Comparison of Mouse Models Reveals Their Clinical Resemblance to Human Liver Cancer Sun Young Yim,Jae‐Jun Shim,Ji-Hyun Shin,Yun Seong Jeong,Sanghee Kang,Sang-Bae Kim,Young‐Gyu Eun,Dong Jin Lee,Elizabeth A. Conner,Valentina M. Factor,David D. Moore,Randy L. Johnson,Snorri S. Thorgeirsson,Ju‐Seog Lee	2018	16
6	Antitumor Effects in Hepatocarcinoma of Isoform-Selective Inhibition of HDAC2 Yun-Han Lee,Daekwan Seo,Kyung‐Ju Choi,Jesper B. Andersen,Min-Ah Won,Mitsuteru Kitade,Luis E. Gómez-Quiroz,Adam D. Judge,Jens U. Marquardt,Chiara Raggi,Elizabeth A. Conner,Ian MacLachlan,Valentina M. Factor,Snorri S. Thorgeirsson	2014	77
7	Loss of the Nucleosome-Binding Protein HMGN1 Affects the Rate of N-Nitrosodiethylamine-Induced Hepatocarcinogenesis in Mice Yuri V. Postnikov,Takashi Furusawa,Diana C. Haines,Valentina M. Factor,Michael Bustin	2013	10
8	Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling Mitsuteru Kitade,Valentina M. Factor,Jesper B. Andersen,Akira Tomokuni,Kosuke Kaji,Hirofumi Akita,Ágnes Holczbauer,Daekwan Seo,Jens U. Marquardt,Elizabeth A. Conner,Seung Bum Lee,Yun‐Han Lee,Snorri S. Thorgeirsson	2013	80
9	Loss of c-Met accelerates development of liver fibrosis in response to CCl4 exposure through deregulation of multiple molecular pathways Jens U. Marquardt,Daekwan Seo,Luis E. Gómez-Quiroz,Koichi Uchida,Matthew C. Gillen,Mitsuteru Kitade,Pál Kaposi-Novák,Elizabeth A. Conner,Valentina M. Factor,Snorri S. Thorgeirsson	2012	67
10	Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways Jens U. Marquardt,Chiara Raggi,Jesper B. Andersen,Daekwan Seo,Itzhak Avital,David A. Geller,Yun Han Lee,Mitsuteru Kitade,Ágnes Holczbauer,Matthew C. Gillen,Elizabeth A. Conner,Valentina M. Factor,Snorri S. Thorgeirsson	2011	63
11	Definition of Ubiquitination Modulator COP1 as a Novel Therapeutic Target in Human Hepatocellular Carcinoma Yun-Han Lee,Jesper B. Andersen,Ho‐Taek Song,Adam D. Judge,Daekwan Seo,Tsuyoshi Ishikawa,Jens U. Marquardt,Mitsuteru Kitade,Marian E. Durkin,Chiara Raggi,Hyun Goo Woo,Elizabeth A. Conner,Itzhak Avital,Ian MacLachlan,Valentina M. Factor,Snorri S. Thorgeirsson	2010	60
12	Loss of c-Met Disrupts Gene Expression Program Required for G2/M Progression during Liver Regeneration in Mice Valentina M. Factor,Daekwan Seo,Tsuyoshi Ishikawa,Pál Kaposi-Novák,Jens U. Marquardt,Jesper B. Andersen,Elizabeth A. Conner,Snorri S. Thorgeirsson	2010	59
13	Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis Pál Kaposi-Novák,Louis Libbrecht,Hyun Goo Woo,Yun‐Han Lee,Nathaniel C. Sears,Elizabeth A. Conner,Valentina M. Factor,Tania Roskams,Snorri S. Thorgeirsson	2009	149
14	Loss of Hepatocyte Growth Factor/c-Met Signaling Pathway Accelerates Early Stages of N -nitrosodiethylamine–Induced Hepatocarcinogenesis Taro Takami,Pál Kaposi-Novák,Koichi Uchida,Luis E. Gómez-Quiroz,Elizabeth A. Conner,Valentina M. Factor,Snorri S. Thorgeirsson	2007	80
15	Molecular pathogenesis of human hepatocellular carcinoma: Mechanistic and prognostic significance of aberrant methylation Diego F. Calvisi,Sara Ladu,Alexis Gorden,Miriam Farina,Ju‐Seog Lee,Elizabeth A. Conner,Insa S. Schroeder,Valentina M. Factor,Snorri S. Thorgeirsson	2006	2
16	HGF/c-met expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and an aggressive phenotype Pál Kaposi-Novák,Ju‐Seog Lee,Luis E. Gómez-Quiroz,Cédric Coulouarn,Valentina M. Factor,Snorri S. Thorgeirsson	2006	1
17	Loss of HGF/c-met signaling pathway accelerates early stages of DEN-induced hepatocarcinogenesis Taro Takami,Kiochi Uchida,Pál Kaposi-Novák,Elizabeth A. Conner,Valentina M. Factor,Snorri S. Thorgeirsson	2006	1
18	Co-expression of c-Myc and E2F1 in a mouse model of liver cancer suppresses apoptosis through activation of Akt/mTOR/p70S6K and COX-2 pathways: relevance for human hepatocellular carcinoma Sara Ladu,Diego F. Calvisi,Elizabeth A. Conner,Valentina M. Factor,Snorri S. Thorgeirsson	2005	1
19	Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice Sergey V. Novoselov,Diego F. Calvisi,Vyacheslav M. Labunskyy,Valentina M. Factor,Bradley A. Carlson,Dmitri E. Fomenko,Mohamed E. Moustafa,Dolph L. Hatfield,Vadim N. Gladyshev	2005	98
20	Regulation of α-Fetoprotein by Nuclear Factor-κB Protects Hepatocytes from Tumor Necrosis Factor-α Cytotoxicity during Fetal Liver Development and Hepatic Oncogenesis Lakita G. Cavin,Venkatraman Manickam,Valentina M. Factor,Swayamjot Kaur,Insa S. Schroeder,Frank Mercurio,Amer A. Beg,Snorri S. Thorgeirsson,Marcello Arsura	2004	32

About Valentina M. Factor

Valentina M. Factor is a scholar working on Hepatology, Cancer Research and Oncology, having authored 109 papers that have together received 8.7k indexed citations. Recurring topics across this work include Liver physiology and pathology (33 papers), Cancer-related Molecular Pathways (23 papers), Epigenetics and DNA Methylation (11 papers), RNA modifications and cancer (11 papers), Liver Disease Diagnosis and Treatment (10 papers), Cancer-related gene regulation (9 papers), TGF-β signaling in diseases (9 papers) and Pancreatic function and diabetes (9 papers). The work is most often cited by research in Hepatology (2.7k citations), Cancer Research (2.2k citations) and Oncology (2.1k citations). Valentina M. Factor has collaborated with scholars based in United States, South Korea and Russia. Frequent co-authors include Snorri S. Thorgeirsson, Elizabeth A. Conner, Jesper B. Andersen, Diego F. Calvisi, Cédric Coulouarn, Sara Ladu, Jens U. Marquardt, S S Thorgeirsson, Marian E. Durkin and Aranzazu Sánchez.

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