Vadivel Ganapathy

41.7k total citations · 8 hit papers
505 papers, 33.9k citations indexed

About

Vadivel Ganapathy is a scholar working on Molecular Biology, Biochemistry and Oncology. According to data from OpenAlex, Vadivel Ganapathy has authored 505 papers receiving a total of 33.9k indexed citations (citations by other indexed papers that have themselves been cited), including 255 papers in Molecular Biology, 169 papers in Biochemistry and 135 papers in Oncology. Recurrent topics in Vadivel Ganapathy's work include Amino Acid Enzymes and Metabolism (162 papers), Drug Transport and Resistance Mechanisms (123 papers) and Metabolism and Genetic Disorders (66 papers). Vadivel Ganapathy is often cited by papers focused on Amino Acid Enzymes and Metabolism (162 papers), Drug Transport and Resistance Mechanisms (123 papers) and Metabolism and Genetic Disorders (66 papers). Vadivel Ganapathy collaborates with scholars based in United States, Japan and Germany. Vadivel Ganapathy's co-authors include Frederick H. Leibach, Puttur D. Prasad, Muthusamy Thangaraju, Sylvia B. Smith, Yangzom D. Bhutia, Pamela M. Martin, Ramesh Kekuda, Malliga E. Ganapathy, You-Jun Fei and Wei Huang and has published in prestigious journals such as Nature, Chemical Reviews and Proceedings of the National Academy of Sciences.

In The Last Decade

Vadivel Ganapathy

499 papers receiving 33.3k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

2014 1.8k citations Nagendra Singh, Sathish Sivaprakasam et al. profile →
The Cystine/Glutamate Antiporter System x _c ⁻ in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

2012 767 citations Sylvia B. Smith, Vadivel Ganapathy et al. Antioxidants and Redox Signaling profile →
Expression cloning of a mammalian proton-coupled oligopeptide transporter

1994 748 citations Vadivel Ganapathy et al. profile →
Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

1993 737 citations Vadivel Ganapathy et al. profile →
GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

2009 622 citations Muthusamy Thangaraju, Kebin Liu et al. Cancer Research profile →
Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond

2008 572 citations Vadivel Ganapathy, Muthusamy Thangaraju et al. profile →
Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon

2019 322 citations Vadivel Ganapathy et al. profile →
Metabolic reprogramming of macrophages by a nano-sized opsonization strategy to restore M1/M2 balance for osteoarthritis therapy

2025 19 citations Ruijie Chen, Huirong Huang et al. Journal of Controlled Release profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Vadivel Ganapathy United States	97	17.4k	7.6k	6.8k	4.1k	3.9k	505	33.9k
Yoshikatsu Kanai Japan	85	13.3k 0.8×	6.7k 0.9×	10.6k 1.6×	3.0k 0.7×	1.7k 0.4×	324	27.9k
Sten Orrenius Sweden	122	28.6k 1.6×	5.3k 0.7×	4.2k 0.6×	1.3k 0.3×	4.8k 1.2×	455	51.5k
Csaba Szabó United States	117	16.1k 0.9×	8.6k 1.1×	13.5k 2.0×	1.2k 0.3×	11.5k 2.9×	682	51.1k
Matthias A. Hediger United States	90	14.8k 0.9×	4.0k 0.5×	4.8k 0.7×	1.7k 0.4×	2.9k 0.8×	256	33.5k
Michael P. Murphy United Kingdom	121	33.6k 1.9×	2.2k 0.3×	4.2k 0.6×	1.4k 0.4×	12.0k 3.1×	535	56.2k
Andrew P. Halestrap United Kingdom	97	22.5k 1.3×	2.6k 0.3×	2.5k 0.4×	982 0.2×	6.7k 1.7×	228	35.3k
Puttur D. Prasad United States	73	8.4k 0.5×	3.1k 0.4×	3.3k 0.5×	1.8k 0.5×	2.0k 0.5×	172	15.8k
Tetsuya Terasaki Japan	75	6.0k 0.3×	8.2k 1.1×	2.1k 0.3×	3.8k 0.9×	2.5k 0.6×	406	19.4k
Ronald J. A. Wanders Netherlands	102	32.0k 1.8×	2.3k 0.3×	4.3k 0.6×	2.1k 0.5×	8.2k 2.1×	828	42.4k
Toren Finkel United States	97	30.3k 1.7×	4.9k 0.7×	2.4k 0.4×	946 0.2×	11.4k 2.9×	211	55.4k

Countries citing papers authored by Vadivel Ganapathy

Since Specialization

Citations

This map shows the geographic impact of Vadivel Ganapathy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Vadivel Ganapathy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Vadivel Ganapathy more than expected).

Fields of papers citing papers by Vadivel Ganapathy

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Vadivel Ganapathy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Vadivel Ganapathy. The network helps show where Vadivel Ganapathy may publish in the future.

Co-authorship network of co-authors of Vadivel Ganapathy

This figure shows the co-authorship network connecting the top 25 collaborators of Vadivel Ganapathy. A scholar is included among the top collaborators of Vadivel Ganapathy based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Vadivel Ganapathy. Vadivel Ganapathy is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chen, Ruijie, Huirong Huang, Chenyu Qiu, et al.. (2025). Metabolic reprogramming of macrophages by a nano-sized opsonization strategy to restore M1/M2 balance for osteoarthritis therapy. Journal of Controlled Release. 380. 469–489. 19 indexed citations breakdown →

Sivaprakasam, Sathish, et al.. (2024). Colonic ketogenesis, a microbiota-regulated process, contributes to blood ketones and protects against colitis in mice. Biochemical Journal. 481(4). 295–312. 1 indexed citations

Bailoo, Jeremy D., Susan E. Bergeson, Igor Ponomarev, et al.. (2024). A bespoke water T–maze apparatus and protocol: an optimized, reliable, and repeatable method for screening learning, memory, and executive functioning in laboratory mice. Frontiers in Behavioral Neuroscience. 18. 1492327–1492327.

Sivaprakasam, Sathish, et al.. (2022). Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues. Bioscience Reports. 43(1). 15 indexed citations

Babu, Ellappan, et al.. (2019). 哺乳類細胞における栄養補助剤β-ヒドロキシ-β-メチルブチラート(HMB)の輸送機構【JST・京大機械翻訳】. Pharmaceutical Research. 36(6). 1–14. 2 indexed citations

Kou, Longfa, Yangzom D. Bhutia, Qing Yao, et al.. (2018). Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types. Frontiers in Pharmacology. 9. 27–27. 243 indexed citations

Powell, Folami Lamoke, Menaka C. Thounaojam, Shanu Markand, et al.. (2016). Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease. Antioxidants and Redox Signaling. 25(17). 921–935. 17 indexed citations

Bardhan, Kankana, Amy V. Paschall, Dafeng Yang, et al.. (2015). IFNγ Induces DNA Methylation–Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer. Cancer Immunology Research. 3(7). 795–805. 40 indexed citations

Elangovan, Selvakumar, Rajneesh Pathania, Sabarish Ramachandran, et al.. (2013). The Niacin/Butyrate Receptor GPR109A Suppresses Mammary Tumorigenesis by Inhibiting Cell Survival. Cancer Research. 74(4). 1166–1178. 106 indexed citations

10.

Mohamed, Riyaz, Calpurnia Jayakumar, Punithavathi Ranganathan, Vadivel Ganapathy, & Ganesan Ramesh. (2012). Kidney Proximal Tubular Epithelial-Specific Overexpression of Netrin-1 Suppresses Inflammation and Albuminuria through Suppression of COX-2-Mediated PGE2 Production in Streptozotocin-Induced Diabetic Mice. American Journal Of Pathology. 181(6). 1991–2002. 67 indexed citations

11.

Ananth, Sudha, et al.. (2012). The Anti-inflammatory Receptor GPR109A Regulates Angiopoeitin-like-4 (ANGPTL4) Expression in Retina: Potential New Link Between Regulation of Inflammatory and Angiogenic Signaling Mechanisms in Diabetic Retina. Investigative Ophthalmology & Visual Science. 53(14). 5777–5777. 1 indexed citations

12.

Li, Yong, Maoxiang Zhang, Huijun Chen, et al.. (2010). Ratio of miR-196s to HOXC8 Messenger RNA Correlates with Breast Cancer Cell Migration and Metastasis. Cancer Research. 70(20). 7894–7904. 126 indexed citations

13.

Metzner, Linda, et al.. (2008). Mutational analysis of histidine residues in the human proton-coupled amino acid transporter PAT1. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1778(4). 1042–1050. 21 indexed citations

14.

Seymour, Robert L., Vadivel Ganapathy, Andrew L. Mellor, & David H. Munn. (2006). A high-affinity, tryptophan-selective amino acid transport system in human macrophages. Journal of Leukocyte Biology. 80(6). 1320–1327. 57 indexed citations

15.

Thangaraju, Muthusamy, Elangovan Gopal, Pamela M. Martin, et al.. (2006). SLC5A8 Triggers Tumor Cell Apoptosis through Pyruvate-Dependent Inhibition of Histone Deacetylases. Cancer Research. 66(24). 11560–11564. 122 indexed citations

16.

Jansson, Nina, Allah Haafiz, Anette Ericsson, et al.. (2006). Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet. The Journal of Physiology. 576(3). 935–946. 126 indexed citations

17.

Hatanaka, Takahiro, et al.. (2006). Amino Acid Transporter ATA2 Is Stored at the trans-Golgi Network and Released by Insulin Stimulus in Adipocytes. Journal of Biological Chemistry. 281(51). 39273–39284. 47 indexed citations

18.

Chen, Zhong, et al.. (2004). Serine Racemase and D-Serine Transport in Human Placenta and Evidence for a Transplacental Gradient for D-Serine in Humans. Journal of the Society for Gynecologic Investigation. 11(5). 294–303. 14 indexed citations

19.

Friedrich, Anne, Puttur D. Prasad, Dorette Freyer, Vadivel Ganapathy, & Peter Brust. (2003). Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood–brain barrier. Brain Research. 968(1). 69–79. 35 indexed citations

20.

Ganapathy, Vadivel, et al.. (2002). Induction of the Cystine/Glutamate Transporter x -c by HIV-1 Transactivator Protein TAT in the Human Retinal Pigment Epithelial Cell Line ARPE-19. Investigative Ophthalmology & Visual Science. 43(13). 4565–4565. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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