Tyson V. Sharp

2.1k citations

48 papers · 1.6k · h-index 24

Impact in

Cancer Research top 5%
- MicroRNA in disease regulation
Immunology top 10%
- interferon and immune responses

Papers in

Molecular Biology 29
- RNA modifications and cancer 9
- RNA Research and Splicing 7
- RNA regulation and disease 6
Cancer Research 17
- Cancer, Hypoxia, and Metabolism 7
- MicroRNA in disease regulation 5
- Cancer-related molecular mechanisms research 4

Co-authors: Michael J. Clemens (5 shared papers)Ian W. Jeffrey (4 shared papers)Rosemary Jagus (3 shared papers)Dimitris Lagos (6 shared papers)Kunal Shah (7 shared papers)Hsei–Wei Wang (3 shared papers)Chris Boshoff (3 shared papers)Tristan R. McKay (5 shared papers)
Journals: Nucleic Acids Research (3 papers)Proceedings of the National Academy of Sciences (3 papers)European Journal of Biochemistry (3 papers)Virology (2 papers)Stem Cell Research (2 papers)
Partner nations: United Kingdom United States India

In The Last Decade

Tyson V. Sharp

46 papers receiving 1.6k citations

Peers

Countries citing papers authored by Tyson V. Sharp

Since Specialization

Citations

This map shows the geographic impact of Tyson V. Sharp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tyson V. Sharp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tyson V. Sharp more than expected).

Fields of papers citing papers by Tyson V. Sharp

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tyson V. Sharp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tyson V. Sharp. The network helps show where Tyson V. Sharp may publish in the future.

Co-authors

The 25 scholars most cited alongside Tyson V. Sharp, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tyson V. Sharp Line = papers co-authored together Tyson V. Sharp links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

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#	Work
1	K15 Protein of Kaposi’s Sarcoma-Associated Herpesvirus Is Latently Expressed and Binds to HAX-1, a Protein with Antiapoptotic Function Journal of Virology ·Tyson V. Sharp, Hsei–Wei Wang, Andrew Koumi, Daniel Hollyman, Yoshio Endo, Hongtao Ye, Ming‐Qing Du, Chris Boshoff	2002	163
2	Comparative analysis of the regulation of the interferoninducible protein kinase PKR by Epstein - Barr virus RNAs EBER-1 and EBER-2 and adenovirus VA, RNA Nucleic Acids Research ·Tyson V. Sharp, Martin Schwemmle, Ian W. Jeffrey, Ken Laing, (unknown), Christopher G. Proud, Kurt Hilse, Michael J. Clemens	1993	155
3	MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells Journal of Biological Chemistry ·Daniel Yee, Kunal Shah, Mark Coles, Tyson V. Sharp, Dimitris Lagos	2017	113
4	The Vaccinia Virus E3L Gene Product Interacts with both the Regulatory and the Substrate Binding Regions of PKR: Implications for PKR Autoregulation Virology ·Tyson V. Sharp, Francis Moonan, Alla M. Romashko, Bharti Joshi, Glen N. Barber, Rosemary Jagus	1998	100
5	The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity Nature Cell Biology ·Daniel E. Foxler, Katherine S. Bridge, Victoria James, Thomas M. Webb, Maureen Mee, Sybil C.K. Wong, Yunfeng Feng, Dumitru Constantin‐Teodosiu, Thorgunnur Eyfjord Petursdottir, Jóhannes Björnsson, Sigurður Ingvarsson, Peter J. Ratcliffe, Gregory D. Longmore, Tyson V. Sharp	2012	75
6	SMG-1 and mTORC1 Act Antagonistically to Regulate Response to Injury and Growth in Planarians PLoS Genetics ·Cristina González‐Estévez, Daniel A. Felix, Matthew D. Smith, Jordi Paps, Simon Morley, Victoria James, Tyson V. Sharp, Aziz Aboobaker	2012	73
7	LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription Proceedings of the National Academy of Sciences ·Tyson V. Sharp, Fernando Muñoz, Dimitra Bourboulia, Nadège Presneau, Eva Darai, Hsei–Wei Wang, Mark Cannon, David N. Butcher, Andrew G. Nicholson, George Klein, Stephan Imreh, Chris Boshoff	2004	68
8	The M Type K15 Protein of Kaposi's Sarcoma-Associated Herpesvirus Regulates MicroRNA Expression via Its SH2-Binding Motif To Induce Cell Migration and Invasion Journal of Virology ·Yuan-Hau Tsai, Min-Fen Wu, Yu-Hsuan Wu, Shing‐Jyh Chang, Su‐Fang Lin, Tyson V. Sharp, Hsei–Wei Wang	2008	59
9	The Role of Hypoxia in Stem Cell Potency and Differentiation Regenerative Medicine ·Kate Hawkins, Tyson V. Sharp, Tristan R. McKay	2013	58
10	LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing Proceedings of the National Academy of Sciences ·Victoria James, Yining Zhang, Daniel E. Foxler, Cornelia H. de Moor, Yi Wen Kong, Thomas M. Webb, Tim Self, Yunfeng Feng, Dimitris Lagos, Chia‐Ying Chu, Tariq M. Rana, Simon Morley, Gregory D. Longmore, Martin Bushell, Tyson V. Sharp	2010	53
11	The La antigen inhibits the activation of the interferoninducible protein kinase PKR by sequestering and unwinding double-stranded RNA Nucleic Acids Research ·Qiurong Xao, Tyson V. Sharp, Ian W. Jeffrey, Marion C. James, Ger J.M. Pruijn, Walther J. van Venrooij, Michael J. Clemens	1994	52
12	Regulation of the interferon-inducible eIF-2α protein kinase by small RNAs Biochimie ·M J Clemens, Ken Laing, Ian W. Jeffrey, A. Schofield, Tyson V. Sharp, Androulla Elia, Volker Matys, Marion C. James, Vivienne J. Tilleray	1994	51
13	Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins Cell Reports ·Katherine S. Bridge, Kunal Shah, Yigen Li, Daniel E. Foxler, Sybil C.K. Wong, Duncan C. Miller, Kathryn M Davidson, John G. Foster, Ruth‐Sarah Rose, Michael R. Hodgkinson, Paulo S. Ribeiro, Aziz Aboobaker, Kenta Yashiro, Xiaozhong Wang, Paul R. Graves, Michael J. Plevin, Dimitris Lagos, Tyson V. Sharp	2017	49
14	Homologous Regions of the α Subunit of Eukaryotic Translational Initiation Factor 2 (eIF2α) and the Vaccinia Virus K3L Gene Product Interact with the Same Domain within the dsRNA‐Activated Protein Kinase (PKR) European Journal of Biochemistry ·Tyson V. Sharp, J. Eric Witzel, Rosemary Jagus	1997	48
15	The chromosome 3p21.3-encoded gene, LIMD1 , is a critical tumor suppressor involved in human lung cancer development Proceedings of the National Academy of Sciences ·Tyson V. Sharp, Ahmad Al‐Attar, Daniel E. Foxler, Li Ding, Thomas Q. de Aguiar Vallim, Yining Zhang, Hala Nijmeh, Thomas M. Webb, Andrew G. Nicholson, Qunyuan Zhang, Aldi T. Kraja, Ian Spendlove, John R. Osborne, Elaine R. Mardis, Gregory D. Longmore	2008	46
16	CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma Cancer Research ·Andrew Feber, Daniel C. Worth, Ankur Chakravarthy, Patricia de Winter, Kunal Shah, Manit Arya, Muhammad Saqib, Raj Nigam, Peter R. Malone, Wei Shen Tan, Simon Rodney, Alex Freeman, Charles Jameson, Gareth A. Wilson, Tom Powles, Stephan Beck, Tim R. Fenton, Tyson V. Sharp, Asıf Muneer, John D. Kelly	2016	46
17	The Hypoxic Tumor Microenvironment: Driving the Tumorigenesis of Non-Small-Cell Lung Cancer Future Oncology ·John G. Foster, Sybil C.K. Wong, Tyson V. Sharp	2014	42
18	BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity American Journal of Physiology-Lung Cellular and Molecular Physiology ·Mustafa M. Munye, Amelia Shoemark, Robert A. Hirst, Juliette Delhove, Tyson V. Sharp, Tristan R. McKay, Christopher O’Callaghan, Deborah L. Baines, Steven J. Howe, Stephen L. Hart	2016	33
19	Reversal of the double‐stranded‐RNA‐induced inhibition of protein synthesis by a catalytically inactive mutant of the protein kinase PKR European Journal of Biochemistry ·Tyson V. Sharp, Qiurong Xiao, Ian W. Jeffrey, Dirk R. Gewert, Michael J. Clemens	1993	33
20	Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition Oncogene ·Maria Dermit, Pedro Casado, Vinothini Rajeeve, Edmund H. Wilkes, Daniel E. Foxler, Hayley Campbell, Susan E. Critchlow, Tyson V. Sharp, John G. Gribben, Robert J. Unwin, Pedro R. Cutillas	2016	26

About Tyson V. Sharp

Tyson V. Sharp is a scholar working on Molecular Biology, Cancer Research, Oncology, Pulmonary and Respiratory Medicine and Surgery, having authored 48 papers that have together received 1.6k indexed citations. Recurring topics across this work include RNA modifications and cancer (9 papers), RNA Research and Splicing (7 papers), Cancer, Hypoxia, and Metabolism (7 papers), RNA regulation and disease (6 papers), Viral-associated cancers and disorders (5 papers), MicroRNA in disease regulation (5 papers), interferon and immune responses (4 papers) and Cancer-related molecular mechanisms research (4 papers). The work is most often cited by research in Cancer Research (303 citations), Immunology (300 citations), Virology (61 citations), Oncology (338 citations) and Molecular Biology (909 citations). Tyson V. Sharp has collaborated with scholars based in United Kingdom, United States and India. Frequent co-authors include Michael J. Clemens, Ian W. Jeffrey, Rosemary Jagus, Dimitris Lagos, Kunal Shah, Hsei–Wei Wang, Chris Boshoff, Tristan R. McKay, Daniel Yee and Ken Laing. Their work appears in journals such as Nucleic Acids Research, Proceedings of the National Academy of Sciences, European Journal of Biochemistry, Virology and Stem Cell Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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