Tsuyoshi Adachi

1.6k citations

20 papers · 1.2k indexed · h-index 12

Co-authors: Noriyuki Habuka Hideo Ago Kimio Yatsunami John Wickersham Zuzana Hostomska Robert A. Love Zdeněk Hostomský Hans E. Parge
Topics: Hepatitis C virus research (7 papers)HIV/AIDS drug development and treatment (7 papers)Biochemical and Molecular Research (6 papers)
Cited by: Hepatology Virology Infectious Diseases
Journals: Cell Biochemistry Scientific Reports
Partner nations: Japan United States

In The Last Decade

Tsuyoshi Adachi

20 papers receiving 1.1k citations

Peers

Countries citing papers authored by Tsuyoshi Adachi

Since Specialization

Citations

This map shows the geographic impact of Tsuyoshi Adachi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tsuyoshi Adachi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tsuyoshi Adachi more than expected).

Fields of papers citing papers by Tsuyoshi Adachi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tsuyoshi Adachi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tsuyoshi Adachi. The network helps show where Tsuyoshi Adachi may publish in the future.

Co-authorship network of co-authors of Tsuyoshi Adachi

This figure shows the co-authorship network connecting the top 25 collaborators of Tsuyoshi Adachi. A scholar is included among the top collaborators of Tsuyoshi Adachi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tsuyoshi Adachi. Tsuyoshi Adachi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety 2024 ·Bioorganic & Medicinal Chemistry Letters ·K. Adachi,(unknown),(unknown),(unknown),(unknown),(unknown),Tsuyoshi Adachi,(unknown),(unknown),Susumu Miyazaki	1
2	Optimization Efforts for Identification of Novel Highly Potent Keap1-Nrf2 Protein–Protein Interaction Inhibitors 2024 ·Journal of Medicinal Chemistry ·(unknown),Yoshinori Hara,Minoru Ubukata,Masafumi Inoue,(unknown),(unknown),Naoki Ogawa,(unknown),(unknown),Tsuyoshi Adachi,Akihiro Nomura,(unknown),(unknown),(unknown),Takahisa Motomura,Motohide Sato,(unknown)	3
3	Methyl and Fluorine Effects in Novel Orally Bioavailable Keap1–Nrf2 PPI Inhibitor 2023 ·ACS Medicinal Chemistry Letters ·(unknown),Minoru Ubukata,(unknown),Naoki Ogawa,(unknown),(unknown),Tsuyoshi Adachi,Akihiro Nomura,(unknown),(unknown),(unknown),Takahisa Motomura,Motohide Sato,(unknown)	14
4	Screening approaches for the identification of Nrf2-Keap1 protein-protein interaction inhibitors targeting hot spot residues 2023 ·SLAS DISCOVERY ·(unknown),(unknown),(unknown),François Debaene,Akihiro Nomura,(unknown),Tsuyoshi Adachi,(unknown),(unknown),(unknown)	3
5	Fragment-Based Discovery of Novel VE-PTP Inhibitors Using Orthogonal Biophysical Techniques 2023 ·Biochemistry ·(unknown),Kenji Yamanaka,(unknown),(unknown),Satoki Doi,(unknown),(unknown),Tsuyoshi Adachi,Shingo Fujioka,(unknown),Kazutaka Ikegashira,(unknown)	2
6	Discovery of Novel NLRP3 Inflammasome Inhibitors Composed of an Oxazole Scaffold Bearing an Acylsulfamide 2023 ·ACS Medicinal Chemistry Letters ·Yusuke Ohba,K. Adachi,Takayuki Furukawa,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Tsuyoshi Adachi,Kenji Usui,Yuji Hamada,(unknown),(unknown),Takeshi Wakashima,(unknown),Susumu Miyazaki,Satoru Noji	5
7	Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases 2021 ·Bioorganic & Medicinal Chemistry ·(unknown),(unknown),Takashi Ito,Shingo Fujioka,Minoru Ubukata,(unknown),Kenji Yamanaka,(unknown),Satoki Doi,(unknown),Kazutaka Ikegashira,(unknown),Isao Nakanishi,Tsuyoshi Adachi	11
8	Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors 2021 ·Bioorganic & Medicinal Chemistry ·(unknown),(unknown),Yoshinori Hara,(unknown),Shingo Obika,(unknown),Minoru Ubukata,Katsutaka Yasue,(unknown),(unknown),(unknown),Satoki Doi,(unknown),(unknown),Tsuyoshi Adachi,Hiroshi Ueno,Takahisa Motomura	3
9	Speeding drug discovery targeting RNAs: An iterative “RNA selection-compounds screening cycle“ for exploring RNA-small molecule pairs 2021 ·Bioorganic & Medicinal Chemistry ·(unknown),Asako Murata,Satoshi Okuda,Kenji Mizutani,Tsuyoshi Adachi,Kazuhiko Nakatani	1
10	Discovery of Selective Transforming Growth Factor β Type II Receptor Inhibitors as Antifibrosis Agents 2021 ·ACS Medicinal Chemistry Letters ·(unknown),Masahiro Yokota,(unknown),Katsuya Maeda,(unknown),(unknown),Naoki Ogawa,(unknown),Akihiro Nomura,Tsuyoshi Adachi,Yuki Kitao,(unknown),Tomohiro Ishikawa,Yutaka Ukaji,Makoto Shiozaki	9
11	Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders 2020 ·Journal of Medicinal Chemistry ·Satoru Noji,Yoshinori Hara,Tomoya Miura,Hiroshi Yamanaka,Katsuya Maeda,(unknown),Hiroshi Yamamoto,Shingo Obika,Masafumi Inoue,Yasunori Hase,(unknown),Satoki Doi,Tsuyoshi Adachi,Atsuo Tanimoto,(unknown),Yukari Kimoto,Yoshihiro Ogawa,(unknown),Hiromasa Hashimoto,Makoto Shiozaki	44
12	Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models 2018 ·Bioorganic & Medicinal Chemistry Letters ·Kazutaka Ikegashira,(unknown),(unknown),Yasunori Hase,Takayuki Yamaguchi,(unknown),Satoki Doi,Tsuyoshi Adachi,Yoshihisa Koga,Hiromasa Hashimoto	12
13	Ternary crystal structure of human RORγ ligand-binding-domain, an inhibitor and corepressor peptide provides a new insight into corepressor interaction 2018 ·Scientific Reports ·Masato Noguchi,Akihiro Nomura,Satoki Doi,(unknown),(unknown),Makoto Shiozaki,Katsuya Maeda,Shintaro Hirashima,(unknown),Takayuki Yamaguchi,Yoshiaki Katsuda,Paul D. Crowe,Hai‐Yan Tao,Scott M. Thacher,Tsuyoshi Adachi	14
14	Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase 2012 ·Antimicrobial Agents and Chemotherapy ·Izuru Ando,Tsuyoshi Adachi,Naoki Ogura,(unknown),(unknown),Hiroyuki Abé,Masafumi Kamada,Tōru Noguchi	12
15	Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole 2006 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Takayoshi Suzuki,Shintaro Hirashima,Kenji Mizutani,(unknown),Izuru Ando,Satoru Ikeda,Tsuyoshi Adachi,Hiromasa Hashimoto	109
16	Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors 2006 ·Journal of Medicinal Chemistry ·Kazutaka Ikegashira,Takahiro Oka,Shintaro Hirashima,Satoru Noji,Hiroshi Yamanaka,Yoshinori Hara,Tsuyoshi Adachi,(unknown),Satoki Doi,Yasunori Hase,Tōru Noguchi,Izuru Ando,Naoki Ogura,Satoru Ikeda,Hiromasa Hashimoto	85
17	The essential role of C-terminal residues in regulating the activity of hepatitis C virus RNA-dependent RNA polymerase 2002 ·Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ·Tsuyoshi Adachi,Hideo Ago,Noriyuki Habuka,Kayo Okuda,(unknown),Satoru Ikeda,Kimio Yatsunami	57
18	Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus 1999 ·Structure ·Hideo Ago,Tsuyoshi Adachi,(unknown),Masaki Yamamoto,Noriyuki Habuka,Kimio Yatsunami,Masashi Miyano	339
19	The conformation of hepatitis C virus NS3 proteinase with and without NS4A: a structural basis for the activation of the enzyme by its cofactor 1998 ·Clinical and Diagnostic Virology ·Robert A. Love,Hans E. Parge,John Wickersham,Zdeněk Hostomský,Noriyuki Habuka,Ellen W. Moomaw,Tsuyoshi Adachi,(unknown),Eleanor Dagostino,Zuzana Hostomska	34
20	The Crystal Structure of Hepatitis C Virus NS3 Proteinase Reveals a Trypsin-like Fold and a Structural Zinc Binding Site 1996 ·Cell ·Robert A. Love,Hans E. Parge,John Wickersham,Zdeněk Hostomský,Noriyuki Habuka,Ellen W. Moomaw,Tsuyoshi Adachi,Zuzana Hostomska	398

About Tsuyoshi Adachi

Tsuyoshi Adachi is a scholar working on Hepatology, Infectious Diseases and Toxicology, having authored 20 papers that have together received 1.2k indexed citations. Recurring topics across this work include Hepatitis C virus research (7 papers), HIV/AIDS drug development and treatment (7 papers) and Biochemical and Molecular Research (6 papers). The work is most often cited by research in Hepatology (694 citations), Virology (94 citations) and Infectious Diseases (305 citations). Tsuyoshi Adachi has collaborated with scholars based in Japan and United States. Frequent co-authors include Noriyuki Habuka, Hideo Ago, Kimio Yatsunami, John Wickersham, Zuzana Hostomska, Robert A. Love, Zdeněk Hostomský, Hans E. Parge, Ellen W. Moomaw and Masaki Yamamoto. Their work appears in journals such as Cell, Biochemistry and Scientific Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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