Trinayan Kashyap

1.6k total citations
57 papers, 934 citations indexed

About

Trinayan Kashyap is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Trinayan Kashyap has authored 57 papers receiving a total of 934 indexed citations (citations by other indexed papers that have themselves been cited), including 49 papers in Molecular Biology, 13 papers in Oncology and 12 papers in Cancer Research. Recurrent topics in Trinayan Kashyap's work include Nuclear Structure and Function (39 papers), Cancer-related Molecular Pathways (9 papers) and Cancer, Lipids, and Metabolism (7 papers). Trinayan Kashyap is often cited by papers focused on Nuclear Structure and Function (39 papers), Cancer-related Molecular Pathways (9 papers) and Cancer, Lipids, and Metabolism (7 papers). Trinayan Kashyap collaborates with scholars based in United States, Belgium and Australia. Trinayan Kashyap's co-authors include Yosef Landesman, Sharon Shacham, Michael Kauffman, Boris Klebanov, William Senapedis, Thaddeus J. Unger, Christian Argueta, Marsha Crochiere, Margaret Lee and Hua Chang and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Oncology and Blood.

In The Last Decade

Trinayan Kashyap

55 papers receiving 932 citations

Peers

Trinayan Kashyap
Yixiao Gong United States
Patrick Jedlowski United States
Jette Ford Australia
Afua A. Mensah Switzerland
Michele Wezeman United States
Trinayan Kashyap
Citations per year, relative to Trinayan Kashyap Trinayan Kashyap (= 1×) peers Jesús Duque‐Afonso

Countries citing papers authored by Trinayan Kashyap

Since Specialization
Citations

This map shows the geographic impact of Trinayan Kashyap's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Trinayan Kashyap with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Trinayan Kashyap more than expected).

Fields of papers citing papers by Trinayan Kashyap

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Trinayan Kashyap. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Trinayan Kashyap. The network helps show where Trinayan Kashyap may publish in the future.

Co-authorship network of co-authors of Trinayan Kashyap

This figure shows the co-authorship network connecting the top 25 collaborators of Trinayan Kashyap. A scholar is included among the top collaborators of Trinayan Kashyap based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Trinayan Kashyap. Trinayan Kashyap is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Fung, Ho Yee Joyce, Tolga Çağatay, Maarten Jacquemyn, et al.. (2025). SINE compounds activate exportin 1 degradation through an allosteric mechanism. Nature Chemical Biology. 21(12). 2002–2013.
3.
Tantravahi, Srinivas K., Ashwin Kishtagari, Sanjay Mohan, et al.. (2024). MPN-527 Selinexor and Ruxolitinib Impact on Symptom Burden in Patients With Myelofibrosis Is Potentially Driven by Inhibition of NF-κB and Activation of P53 Pathways. Clinical Lymphoma Myeloma & Leukemia. 24. S437–S438. 1 indexed citations
4.
Lisiero, Dominique N., et al.. (2022). HAPLN1 confers multiple myeloma cell resistance to several classes of therapeutic drugs. PLoS ONE. 17(12). e0274704–e0274704. 3 indexed citations
5.
Walker, Christopher J., Hua Chang, Trinayan Kashyap, et al.. (2022). Selinexor inhibits growth of patient derived chordomas in vivo as a single agent and in combination with abemaciclib through diverse mechanisms. Frontiers in Oncology. 12. 808021–808021. 4 indexed citations
6.
Toprak, Selami Koçak, Sinem Civriz Bozdağ, Meltem Kurt Yüksel, et al.. (2021). Comparison of Salvage Autologous Hematopoietic Cell Transplantation with Outcomes Following Selinexor Combinations Among Double/Triple Refractory Myeloma Patients. Blood. 138(Supplement 1). 4904–4904. 3 indexed citations
7.
Kashyap, Trinayan, Jackelyn Murray, Christopher J. Walker, et al.. (2021). Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo. Antiviral Research. 192. 105115–105115. 38 indexed citations
8.
DeSisto, John, Patrick Flannery, Amrita Pathak, et al.. (2019). Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma. Molecular Cancer Therapeutics. 19(2). 540–551. 18 indexed citations
9.
Long, Lilia Merida de, Trinayan Kashyap, Christian Argueta, et al.. (2018). Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas. Science Translational Medicine. 10(447). 36 indexed citations
10.
Farren, Matthew R., Reena Shakya, Gregory Young, et al.. (2017). The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors. Molecular Cancer Therapeutics. 16(3). 417–427. 23 indexed citations
11.
Tyler, Paul, Boris Klebanov, Trinayan Kashyap, et al.. (2017). Clinical Dosing Regimen of Selinexor Maintains Normal Immune Homeostasis and T-cell Effector Function in Mice: Implications for Combination with Immunotherapy. Molecular Cancer Therapeutics. 16(3). 428–439. 28 indexed citations
12.
Ranganathan, Parvathi, Trinayan Kashyap, Xueyan Yu, et al.. (2016). XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus. Clinical Cancer Research. 22(24). 6142–6152. 67 indexed citations
13.
Kashyap, Trinayan, Irfana Muqbil, Amro Aboukameel, et al.. (2016). Combination of Selinexor and the Proteasome Inhibitor, Bortezomib Shows Synergistic Cytotoxicity in Diffuse Large B-Cells Lymphoma Cells In Vitro and In Vivo. Blood. 128(22). 4131–4131. 5 indexed citations
14.
Kashyap, Trinayan, Christian Argueta, Amro Aboukameel, et al.. (2016). Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death. Oncotarget. 7(48). 78883–78895. 91 indexed citations
15.
Malafa, Mokenge P., Domenico Coppola, Kazim Husain, et al.. (2015). Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic Cancer. Molecular Cancer Therapeutics. 14(7). 1570–1581. 50 indexed citations
16.
Crochiere, Marsha, Trinayan Kashyap, Ori Kalid, et al.. (2015). Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compounds. BMC Cancer. 15(1). 910–910. 23 indexed citations
17.
Yang, Jennifer, Matthew A. Bill, Gregory Young, et al.. (2014). Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells. PLoS ONE. 9(7). e102983–e102983. 44 indexed citations
18.
Kisseberth, William C., Misty D. Bear, Yosef Landesman, et al.. (2014). Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines. BMC Veterinary Research. 10(1). 160–160. 20 indexed citations
19.
Kashyap, Trinayan & Isaac Rabinovitz. (2012). The Calcium/Calcineurin Pathway Promotes Hemidesmosome Stability through Inhibition of β4 Integrin Phosphorylation. Journal of Biological Chemistry. 287(39). 32440–32449. 10 indexed citations
20.
Kashyap, Trinayan, et al.. (2011). Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration. Laboratory Investigation. 91(10). 1414–1426. 22 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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