Tomoko Smyth

1.0k citations
33 papers · 631 · h-index 12

Impact in

Papers in

  • Molecular Biology 23
    • Heat shock proteins research 7
    • Ubiquitin and proteasome pathways 7
    • ATP Synthase and ATPases Research 5
  • Immunology 12
    • T-cell and Retrovirus Studies 4
    • Immune Response and Inflammation 4
Co-authors
John F. Lyons (16 shared papers)Neil T. Thompson (14 shared papers)Nicola G. Wallis (12 shared papers)Clare Bryant (4 shared papers)Jayne Curry (8 shared papers)Duncan J. Maskell (3 shared papers)Catharine M. Walsh (1 shared paper)Monique Gangloff (1 shared paper)
Journals
Blood (7 papers)Molecular Cancer Therapeutics (6 papers)Cancer Research (5 papers)British Journal of Haematology (1 paper)British Journal of Cancer (1 paper)
Partner nations
United KingdomUnited StatesJapan

In The Last Decade

Tomoko Smyth

31 papers receiving 613 citations

Peers

Tomoko Smyth
Comparison fields: 5 of 74
  • Immunology 202
  • Microbiology 41
  • Equine 10
  • Gastroenterology 32
  • Oncology 159
Replace G. Fendrich with:
G. Fendrich Switzerland
Taj S. Mattu United Kingdom
Trevor Clancy Norway
Bettina Schimmel Germany
Huihua Zhang China
Annett Bleul Germany
Wouter Pos Netherlands
Pascal Crottet Switzerland
Yannick Pilatte France
Eric P. Hanson United States
Tomoko Smyth relative to G. Fendrich Switzerland G. Fendrich's profile →
Citations per field
00.5×2×4×6×8×10×
G. Fendrich · 1×
Citations per year

Countries citing papers authored by Tomoko Smyth

Since Specialization
Citations

This map shows the geographic impact of Tomoko Smyth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tomoko Smyth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tomoko Smyth more than expected).

Fields of papers citing papers by Tomoko Smyth

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tomoko Smyth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tomoko Smyth. The network helps show where Tomoko Smyth may publish in the future.

Co-authors

The 25 scholars most cited alongside Tomoko Smyth, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tomoko Smyth Line = papers co-authored together Tomoko Smyth links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 33 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Elucidation of the MD-2/TLR4 Interface Required for Signaling by Lipid IVa
The Journal of Immunology ·Catharine M. Walsh, Monique Gangloff, Tom P. Monie, Tomoko Smyth, Bin Wei, Trevelyan J. McKinley, Duncan J. Maskell, Nicholas J. Gay, Clare Bryant
2008110
2
Inhibition of HSP90 by AT13387 Delays the Emergence of Resistance to BRAF Inhibitors and Overcomes Resistance to Dual BRAF and MEK Inhibition in Melanoma Models
Molecular Cancer Therapeutics ·Tomoko Smyth, Kim H.T. Paraiso, Keisha Hearn, Ana M. Rodríguez-López, Joanne M. Munck, H. Eirik Haarberg, Vernon K. Sondak, Neil T. Thompson, Mohammad Azab, John F. Lyons, Keiran S.M. Smalley, Nicola G. Wallis
201466
3
The heat shock protein 90 inhibitor, AT13387, displays a long duration of action in vitro and in vivo in non‐small cell lung cancer
Cancer Science ·Brent Graham, Jayne Curry, Tomoko Smyth, Lynsey Fazal, Ruth E. Feltell, Isobel Harada, Joe Coyle, Brian Williams, Matthias Reule, Hayley C. Angove, David M. Cross, John F. Lyons, Nicola G. Wallis, Neil T. Thompson
201165
4
Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL–positive leukemic cells
Blood ·Ruriko Tanaka, Matthew Squires, Shinya Kimura, Asumi Yokota, Rina Nagao, Takahiro Yamauchi, Miki Takeuchi, Hisayuki Yao, Matthias Reule, Tomoko Smyth, John F. Lyons, Neil T. Thompson, Eishi Ashihara, Oliver G. Ottmann, Taira Maekawa
201056
5
ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth
Molecular Cancer Therapeutics ·George A. Ward, Edward J. Lewis, Jong Sook Ahn, Christopher N. Johnson, John F. Lyons, Vanessa Martins, Joanne M. Munck, Sharna J. Rich, Tomoko Smyth, Neil T. Thompson, Pamela A. Williams, Nicola E. Wilsher, Nicola G. Wallis, Gianni Chessari
201853
6
A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation
Molecular Cancer ·King Chi Chan, Choi Man Ting, Pui Shan Chan, Ming Lo, Kwok Wai Lo, Jayne Curry, Tomoko Smyth, Anne Wing Mui Lee, Wai Tong Ng, George S.W. Tsao, Ricky Ngok‐Shun Wong, Maria Li Lung, Nai Ki Mak
201353
7
The HSP90 Inhibitor, AT13387, Is Effective against Imatinib-Sensitive and -Resistant Gastrointestinal Stromal Tumor Models
Molecular Cancer Therapeutics ·Tomoko Smyth, Thomas Van Looy, Jayne Curry, Ana M. Rodrı́guez-López, Agnieszka Woźniak, Mei‐Jun Zhu, Rachel Donsky, Jennifer G. Morgan, Mark Mayeda, Jonathan A. Fletcher, Patrick Schöffski, John F. Lyons, Neil T. Thompson, Nicola G. Wallis
201249
8
AT9283, a potent inhibitor of the Aurora kinases and Jak2, has therapeutic potential in myeloproliferative disorders
British Journal of Haematology ·Mark A. Dawson, Jayne Curry, Kelly Barber, Philip Beer, Brent Graham, John F. Lyons, Caroline J. Richardson, Mike Scott, Tomoko Smyth, Matthew Squires, Neil T. Thompson, Anthony R. Green, Nicola G. Wallis
201041
9
Emergence of resistance to tyrosine kinase inhibitors in non-small-cell lung cancer can be delayed by an upfront combination with the HSP90 inhibitor onalespib
British Journal of Cancer ·Aurélie Courtin, Tomoko Smyth, Keisha Hearn, Harpreet K. Saini, Neil T. Thompson, John F. Lyons, Nicola G. Wallis
201623
10
Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer
Molecular Cancer Therapeutics ·Nyree Crawford, Katie J. Stott, Tamas Sessler, Christopher McCann, William J. McDaid, Andrea Lees, Cheryl H. Latimer, Jennifer Fox, Joanne M. Munck, Tomoko Smyth, Alpesh Shah, Vanessa Martins, Mark Lawler, Philip D. Dunne, Emma Kerr, Simon S. McDade, Vicky M. Coyle, Daniel B. Longley
202121
11
Genotyping of Toll-like receptor 4, myeloid differentiation factor 2 and CD-14 in the horse: An investigation into the influence of genetic polymorphisms on the LPS induced TNF-α response in equine whole blood
Veterinary Immunology and Immunopathology ·Arno Werners, Sarah Bull, J. C. Vendrig, Tomoko Smyth, Remko R. Bosch, Johanna Fink‐Gremmels, Clare Bryant
200619
12
Phase 1 study of the HSP90 inhibitor onalespib in combination with AT7519, a pan-CDK inhibitor, in patients with advanced solid tumors
Cancer Chemotherapy and Pharmacology ·T. Khanh, Geraldine O’Sullivan Coyne, John L. Hays, Jeffrey G. Supko, Stephen V. Liu, Kristin Beebe, Len Neckers, Jane B. Trepel, Min-Jung Lee, Tomoko Smyth, Courtney Gannon, Jennifer Hedglin, Alona Muzikansky, Susana M. Campos, John F. Lyons, Percy Ivy, James H. Doroshow, Alice P. Chen, Geoffrey I. Shapiro
202018
13
Differential modulatory effects of Annexin 1 on nitric oxide synthase induction by lipopolysaccharide in macrophages
Immunology ·Tomoko Smyth, Hayley J. Harris, Andy Brown, Sabine Tötemeyer, Belinda A. Farnfield, Duncan J. Maskell, Makoto Matsumoto, Robin Plevin, Louise Alldridge, Clare Bryant
200510
14
Dexamethasone modulatesSalmonella entericaserovar Typhimurium infectionin vivoindependently of the glucocorticoid-inducible protein annexin-A1
FEMS Immunology & Medical Microbiology ·Tomoko Smyth, Sabine Tötemeyer, Sean Haugland, Chrissie Willers, Sarah E. Peters, Duncan J. Maskell, Clare Bryant
20088
15
Activity of the Multi-Targeted Kinase Inhibitor, AT9283 on Imatinib-Resistant CML Models.
Blood ·Ruriko Tanaka, Matthew Squires, Shinya Kimura, Asumi Yokota, Kirsty Mallett, Tomoko Smyth, Neil T. Thompson, Rina Nagao, Takahiro Yamauchi, Takashi Ushiki, John F. Lyons, Taira Maekawa
20086
16
AT9283, a Potent Inhibitor of JAK2, Is Active in JAK2 V617F Myeloproliferative Disease Models.
Blood ·Matthew Squires, Jayne Curry, Mark A. Dawson, Mike Scott, Kelly Barber, Matthias Reule, Tomoko Smyth, Nicola G. Wallis, Murray Yule, Neil T. Thompson, John F. Lyons, Anthony R. Green
20076
17
Antagonism of inhibitors of apoptosis proteins reveals a novel, immune response-based therapeutic approach for T-cell lymphoma
Blood Advances ·Nicola Ferrari, George A. Ward, Christina Gewinner, Matthew P. Davis, Simone Jueliger, Harpreet K. Saini, Joanne M. Munck, Tomoko Smyth, Roberta Ferraldeschi, Harold Keer, John F. Lyons, Martin Sims
20215
18
Abstract 2433: In vitro and in vivo antitumor activity of the next generation HSP90 inhibitor, AT13387, in both hormone-sensitive and castration-resistant prostate cancer models.
Cancer Research ·Roberta Ferraldeschi, Somaieh Hedayat, Tomoko Smyth, Nicola G. Wallis, John Lyons, Ruth Riisnaes, Mateus Crespo, Daniel Nava Rodrigues, Susana Miranda, Swee Y. Sharp, Gerhardt Attard, Suzanne A. Eccles, Paul Workman, Johann S. de Bono
20134
19
Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma
Cancer Research Communications ·George A. Ward, Zhiqiang Zhang, Simone Jueliger, Ilya S. Potapov, Matthew P. Davis, Adam R. Boxall, Jason Taylor, Harold Keer, Andrea Biondo, John F. Lyons, Martin Sims, Tomoko Smyth
20242
20
Abstract A217: Comparison of long-term pharmacodynamic actions of the synthetic small molecule HSP90 inhibitor AT13387 in multiple xenograft models
Molecular Cancer Therapeutics ·John Lyons, Jayne Curry, Tomoko Smyth, Isobel Harada, Lynsey Fazal, Matthias Reule, Brent Graham, Neil T. Thompson
20092

About Tomoko Smyth

Tomoko Smyth is a scholar working on Molecular Biology, Immunology, Pulmonary and Respiratory Medicine, Oncology and Genetics, having authored 33 papers that have together received 631 indexed citations. Recurring topics across this work include Heat shock proteins research (7 papers), Ubiquitin and proteasome pathways (7 papers), ATP Synthase and ATPases Research (5 papers), Chronic Myeloid Leukemia Treatments (4 papers), T-cell and Retrovirus Studies (4 papers), Immune Response and Inflammation (4 papers), Acute Myeloid Leukemia Research (3 papers) and Lung Cancer Treatments and Mutations (3 papers). The work is most often cited by research in Immunology (202 citations), Microbiology (41 citations), Equine (10 citations), Gastroenterology (32 citations) and Oncology (159 citations). Tomoko Smyth has collaborated with scholars based in United Kingdom, United States and Japan. Frequent co-authors include John F. Lyons, Neil T. Thompson, Nicola G. Wallis, Clare Bryant, Jayne Curry, Duncan J. Maskell, Catharine M. Walsh, Monique Gangloff, Trevelyan J. McKinley and Nicholas J. Gay. Their work appears in journals such as Blood, Molecular Cancer Therapeutics, Cancer Research, British Journal of Haematology and British Journal of Cancer.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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