Kikuko Hotta

24.6k total citations · 8 hit papers
69 papers, 17.0k citations indexed

About

Kikuko Hotta is a scholar working on Epidemiology, Molecular Biology and Physiology. According to data from OpenAlex, Kikuko Hotta has authored 69 papers receiving a total of 17.0k indexed citations (citations by other indexed papers that have themselves been cited), including 32 papers in Epidemiology, 31 papers in Molecular Biology and 20 papers in Physiology. Recurrent topics in Kikuko Hotta's work include Liver Disease Diagnosis and Treatment (18 papers), Adipokines, Inflammation, and Metabolic Diseases (15 papers) and Adipose Tissue and Metabolism (15 papers). Kikuko Hotta is often cited by papers focused on Liver Disease Diagnosis and Treatment (18 papers), Adipokines, Inflammation, and Metabolic Diseases (15 papers) and Adipose Tissue and Metabolism (15 papers). Kikuko Hotta collaborates with scholars based in Japan, United States and Italy. Kikuko Hotta's co-authors include Yūji Matsuzawa, Tohru Funahashi, Hiroshi Kuriyama, Shinji Kihara, Yukio Arita, Noriyuki Ouchi, Tadashi Nakamura, Makoto Nishida, Shizuya Yamashita and P. Antonio Tataranni and has published in prestigious journals such as Journal of Biological Chemistry, Circulation and Molecular and Cellular Biology.

In The Last Decade

Kikuko Hotta

69 papers receiving 16.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

1999 4.1k citations Yukio Arita, Shinji Kihara et al. Biochemical and Biophysical Research Communications profile →
Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia

2001 2.9k citations Tohru Funahashi, Kikuko Hotta et al. profile →
Novel Modulator for Endothelial Adhesion Molecules

1999 1.8k citations Noriyuki Ouchi, Shinji Kihara et al. profile →
Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-κB Signaling Through a cAMP-Dependent Pathway

2000 1.5k citations Noriyuki Ouchi, Shinji Kihara et al. profile →
PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

2001 1.4k citations Masahiko Takahashi, Tohru Funahashi et al. profile →
Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

2001 1.1k citations Noriyuki Ouchi, Shinji Kihara et al. profile →
Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys

2001 870 citations Kikuko Hotta, Tohru Funahashi et al. profile →
Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell

2002 564 citations Yukio Arita, Shinji Kihara et al. profile →

Peers

Kikuko Hotta

EPIDE

PHYSI

CCM

EAS

Yukio Arita Japan

Norikazu Maeda Japan

Hitoshi Nishizawa Japan

Stuart P. Weisberg United States

Anders H. Berg United States

Mathias Faßhauer Germany

Ken Kishida Japan

Anthony W. Ferrante United States

Koji Ohashi Japan

Andrew J. Nichols United States

Yukio Arita Japan

Kikuko Hotta

11.4k ×1.0

EPIDE

6.7k ×0.9

PHYSI

4.4k ×1.1

CCM

2.1k ×0.6

2.8k ×0.9

EAS

Citations per year, relative to Kikuko Hotta Kikuko Hotta (= 1×) peers Yukio Arita

Countries citing papers authored by Kikuko Hotta

Since Specialization

Citations

This map shows the geographic impact of Kikuko Hotta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kikuko Hotta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kikuko Hotta more than expected).

Fields of papers citing papers by Kikuko Hotta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kikuko Hotta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kikuko Hotta. The network helps show where Kikuko Hotta may publish in the future.

Co-authorship network of co-authors of Kikuko Hotta

This figure shows the co-authorship network connecting the top 25 collaborators of Kikuko Hotta. A scholar is included among the top collaborators of Kikuko Hotta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kikuko Hotta. Kikuko Hotta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Kurokawa, Suguru, Takuro Kobori, Masato Yoneda, et al.. (2024). Identification of differentially methylated regions associated with both liver fibrosis and hepatocellular carcinoma. BMC Gastroenterology. 24(1). 57–57. 3 indexed citations

Kurokawa, Suguru, Masato Yoneda, Yuji Ogawa, et al.. (2022). Two differentially methylated region networks in nonalcoholic fatty liver disease, viral hepatitis, and hepatocellular carcinoma. BMC Gastroenterology. 22(1). 278–278. 4 indexed citations

Sato, Shigeru, Takeshi Morimoto, Kikuko Hotta, et al.. (2020). Novel mutation identified in Leber congenital amaurosis - a case report. BMC Ophthalmology. 20(1). 313–313. 2 indexed citations

Sato, Shigeru, Takeshi Morimoto, Kikuko Hotta, Takashi Fujikado, & Kohji Nishida. (2019). A novel compound heterozygous mutation in TTC8 identified in a Japanese patient. Human Genome Variation. 6(1). 14–14. 10 indexed citations

Kitamoto, Takuya, Aya Kitamoto, Yuji Ogawa, et al.. (2015). Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease. Journal of Hepatology. 63(2). 494–502. 66 indexed citations

Matsuo, Tomoaki, Yoshio Nakata, Kikuko Hotta, & Kiyoji Tanaka. (2014). The FTO genotype as a useful predictor of body weight maintenance: Initial data from a 5-year follow-up study. Metabolism. 63(7). 912–917. 16 indexed citations

Xi, Bo, Xiaoyuan Zhao, Yue Shen, et al.. (2013). Associations of obesity susceptibility loci with hypertension in Chinese children. International Journal of Obesity. 37(7). 926–930. 20 indexed citations

Kitamoto, Takuya, Aya Kitamoto, Masato Yoneda, et al.. (2013). Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan. Human Genetics. 132(7). 783–792. 152 indexed citations

Matsuo, Tomoaki, et al.. (2011). Effects of FTO Genotype on Weight Loss and Metabolic Risk Factors in Response to Calorie Restriction Among Japanese Women. Obesity. 20(5). 1122–1126. 21 indexed citations

10.

Lee, Yun Sok, Jin Woo Choi, Injae Hwang, et al.. (2010). Adipocytokine Orosomucoid Integrates Inflammatory and Metabolic Signals to Preserve Energy Homeostasis by Resolving Immoderate Inflammation. Journal of Biological Chemistry. 285(29). 22174–22185. 110 indexed citations

11.

Hotta, Kikuko, Masato Yoneda, Hideyuki Hyogo, et al.. (2010). Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease. BMC Medical Genetics. 11(1). 172–172. 136 indexed citations

12.

Matsuo, Tomoaki, Yoshio Nakata, Yasutomi Katayama, et al.. (2009). PPARG Genotype Accounts for Part of Individual Variation in Body Weight Reduction in Response to Calorie Restriction. Obesity. 17(10). 1924–1931. 38 indexed citations

13.

Yoneda, Masato, Yuichi Nozaki, Hiroki Endo, et al.. (2009). Serum Ferritin Is a Clinical Biomarker in Japanese Patients with Nonalcoholic Steatohepatitis (NASH) Independent of HFE Gene Mutation. Digestive Diseases and Sciences. 55(3). 808–814. 65 indexed citations

14.

Yoneda, Masato, Hiroki Endo, Yuichi Nozaki, et al.. (2007). Life Style-Related Diseases of the Digestive System: Gene Expression in Nonalcoholic Steatohepatitis Patients and Treatment Strategies. Journal of Pharmacological Sciences. 105(2). 151–156. 15 indexed citations

15.

Nakamura, Tadashi, Tohru Funahashi, Shizuya Yamashita, et al.. (2001). Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation—double-blind placebo-controlled trial. Diabetes Research and Clinical Practice. 54(3). 181–190. 87 indexed citations

16.

Hotta, Kikuko, M. Nishida, Kazuaki Kotani, et al.. (2000). Mutation in Bombesin Receptor Subtype-3 Gene is not a Major Cause of Obesity in the Japanese. Hormone and Metabolic Research. 32(1). 33–34. 10 indexed citations

17.

Arita, Yukio, Shinji Kihara, Noriyuki Ouchi, et al.. (1999). Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity. Biochemical and Biophysical Research Communications. 257(1). 79–83. 4054 indexed citations breakdown →

18.

Hotta, Kikuko, Thomas A. Gustafson, Heidi K. Ortmeyer, Noni L. Bodkin, & Barbara C. Hansen. (1998). Monkey Leptin Receptor mRNA: Sequence, Tissue Distribution, and mRNA Expression in the Adipose Tissue of Normal, Hyperinsulinemic, and Type 2 Diabetic Rhesus Monkeys. Obesity Research. 6(5). 353–360. 10 indexed citations

19.

O’Neill, Thomas J., David W. Rose, Tahir S Pillay, et al.. (1996). Interaction of a GRB-IR Splice Variant (a Human GRB10 Homolog) with the Insulin and Insulin-like Growth Factor I Receptors. Journal of Biological Chemistry. 271(37). 22506–22513. 122 indexed citations

20.

Yamasaki, Tomoyuki, Hiromu Nakajima, Norio Kôno, et al.. (1991). Structure of the entire human muscle phosphofructokinase-encoding gene: a two-promoter system. Gene. 104(2). 277–282. 41 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact