Timothy O. Street

2.1k total citations · 1 hit paper
31 papers, 1.7k citations indexed

About

Timothy O. Street is a scholar working on Molecular Biology, Materials Chemistry and Cell Biology. According to data from OpenAlex, Timothy O. Street has authored 31 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 13 papers in Materials Chemistry and 9 papers in Cell Biology. Recurrent topics in Timothy O. Street's work include Protein Structure and Dynamics (23 papers), Heat shock proteins research (19 papers) and Enzyme Structure and Function (13 papers). Timothy O. Street is often cited by papers focused on Protein Structure and Dynamics (23 papers), Heat shock proteins research (19 papers) and Enzyme Structure and Function (13 papers). Timothy O. Street collaborates with scholars based in United States, United Kingdom and Israel. Timothy O. Street's co-authors include George D. Rose, D. Wayne Bolen, David A. Agard, Laura A. Lavery, Kristin A. Krukenberg, Doug Barrick, Naomi Courtemanche, Ming Sun, Nicholas C. Fitzkee and Christina Marchetti Bradley and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Timothy O. Street

31 papers receiving 1.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A molecular mechanism for osmolyte-induced protein stability

2006 562 citations Timothy O. Street, D. Wayne Bolen et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Timothy O. Street United States	18	1.4k	568	223	132	118	31	1.7k
Atsuo Tamura Japan	22	1.3k 0.9×	437 0.8×	137 0.6×	80 0.6×	210 1.8×	65	1.8k
Beatriz Ibarra‐Molero Spain	22	1.6k 1.2×	745 1.3×	185 0.8×	51 0.4×	187 1.6×	44	1.9k
Theresa A. Ramelot United States	21	1.4k 1.0×	371 0.7×	128 0.6×	117 0.9×	162 1.4×	69	1.9k
Michael W. Clarkson United States	18	1.2k 0.9×	392 0.7×	112 0.5×	88 0.7×	228 1.9×	24	1.5k
Jörg Rösgen United States	23	1.5k 1.1×	713 1.3×	209 0.9×	45 0.3×	201 1.7×	39	2.1k
Jeung‐Hoi Ha United States	18	1.4k 1.0×	288 0.5×	107 0.5×	46 0.3×	112 0.9×	34	1.7k
A. Cousido-Siah France	23	851 0.6×	202 0.4×	256 1.1×	76 0.6×	74 0.6×	51	1.5k
Robert Fraczkiewicz United States	10	828 0.6×	283 0.5×	93 0.4×	160 1.2×	141 1.2×	16	1.3k
Honggao Yan United States	28	1.6k 1.2×	407 0.7×	98 0.4×	98 0.7×	79 0.7×	78	2.3k
Kevin L. Shaw United States	11	1.1k 0.8×	493 0.9×	100 0.4×	58 0.4×	119 1.0×	11	1.3k

Countries citing papers authored by Timothy O. Street

Since Specialization

Citations

This map shows the geographic impact of Timothy O. Street's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy O. Street with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy O. Street more than expected).

Fields of papers citing papers by Timothy O. Street

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy O. Street. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy O. Street. The network helps show where Timothy O. Street may publish in the future.

Co-authorship network of co-authors of Timothy O. Street

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy O. Street. A scholar is included among the top collaborators of Timothy O. Street based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy O. Street. Timothy O. Street is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Han, Liping, et al.. (2025). Mechanism of client loading from BiP to Grp94 and its disruption by select inhibitors. Nature Communications. 16(1). 3575–3575. 2 indexed citations

Huang, Bin, et al.. (2022). The endoplasmic reticulum chaperone BiP is a closure-accelerating cochaperone of Grp94. Proceedings of the National Academy of Sciences. 119(5). 20 indexed citations

Shepard, Jaclyn A., Marc D. Breton, Revital Nimri, et al.. (2020). User and Healthcare Professional Perspectives on Do-It-Yourself Artificial Pancreas Systems: A Need for Guidelines. Journal of Diabetes Science and Technology. 16(1). 224–227. 13 indexed citations

Sun, Ming, et al.. (2019). The endoplasmic reticulum (ER) chaperones BiP and Grp94 selectively associate when BiP is in the ADP conformation. Journal of Biological Chemistry. 294(16). 6387–6396. 29 indexed citations

Huang, Bin, Larry J. Friedman, Ming Sun, Jeff Gelles, & Timothy O. Street. (2019). Conformational Cycling within the Closed State of Grp94, an Hsp90-Family Chaperone. Journal of Molecular Biology. 431(17). 3312–3323. 12 indexed citations

Street, Timothy O., et al.. (2019). Multimapping confounds ribosome profiling analysis: A case‐study of the Hsp90 molecular chaperone. Proteins Structure Function and Bioinformatics. 88(1). 57–68. 4 indexed citations

Street, Timothy O., et al.. (2017). Molecular mechanism of bacterial Hsp90 pH‐dependent ATPase activity. Protein Science. 26(6). 1206–1213. 11 indexed citations

Huang, Bin, et al.. (2016). Crowding Activates Heat Shock Protein 90. Journal of Biological Chemistry. 291(12). 6447–6455. 21 indexed citations

Street, Timothy O., Xiaohui Zeng, Riccardo Pellarin, et al.. (2014). Elucidating the Mechanism of Substrate Recognition by the Bacterial Hsp90 Molecular Chaperone. Journal of Molecular Biology. 426(12). 2393–2404. 38 indexed citations

10.

Genest, Olivier, Michael Reidy, Timothy O. Street, et al.. (2012). Uncovering a Region of Heat Shock Protein 90 Important for Client Binding in E. coli and Chaperone Function in Yeast. Molecular Cell. 49(3). 464–473. 99 indexed citations

11.

Street, Timothy O., Laura A. Lavery, Kliment A. Verba, et al.. (2011). Cross-Monomer Substrate Contacts Reposition the Hsp90 N-Terminal Domain and Prime the Chaperone Activity. Journal of Molecular Biology. 415(1). 3–15. 39 indexed citations

12.

Street, Timothy O., Laura A. Lavery, & David A. Agard. (2011). Substrate Binding Drives Large-Scale Conformational Changes in the Hsp90 Molecular Chaperone. Molecular Cell. 42(1). 96–105. 134 indexed citations

13.

Krukenberg, Kristin A., Timothy O. Street, Laura A. Lavery, & David A. Agard. (2011). Conformational dynamics of the molecular chaperone Hsp90. Quarterly Reviews of Biophysics. 44(2). 229–255. 232 indexed citations

14.

Street, Timothy O., Kristin A. Krukenberg, Jörg Rösgen, D. Wayne Bolen, & David A. Agard. (2009). Osmolyte‐induced conformational changes in the Hsp90 molecular chaperone. Protein Science. 19(1). 57–65. 62 indexed citations

15.

Street, Timothy O. & Doug Barrick. (2008). Predicting repeat protein folding kinetics from an experimentally determined folding energy landscape. Protein Science. 18(1). 58–68. 13 indexed citations

16.

Street, Timothy O., et al.. (2008). Structures, basins, and energies: A deconstruction of the Protein Coil Library. Protein Science. 17(7). 1151–1161. 43 indexed citations

17.

Street, Timothy O., Naomi Courtemanche, & Doug Barrick. (2007). Protein Folding and Stability Using Denaturants. Methods in cell biology. 84. 295–325. 57 indexed citations

18.

Street, Timothy O., D. Wayne Bolen, & George D. Rose. (2006). A molecular mechanism for osmolyte-induced protein stability. Proceedings of the National Academy of Sciences. 103(38). 13997–14002. 562 indexed citations breakdown →

19.

Street, Timothy O., Christina Marchetti Bradley, & Doug Barrick. (2005). An improved experimental system for determining small folding entropy changes resulting from proline to alanine substitutions. Protein Science. 14(9). 2429–2435. 10 indexed citations

20.

Fitzkee, Nicholas C., et al.. (2005). Are proteins made from a limited parts list?. Trends in Biochemical Sciences. 30(2). 73–80. 59 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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