Larry J. Friedman

3.3k total citations · 1 hit paper
52 papers, 2.3k citations indexed

About

Larry J. Friedman is a scholar working on Molecular Biology, Atomic and Molecular Physics, and Optics and Genetics. According to data from OpenAlex, Larry J. Friedman has authored 52 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 39 papers in Molecular Biology, 10 papers in Atomic and Molecular Physics, and Optics and 9 papers in Genetics. Recurrent topics in Larry J. Friedman's work include RNA and protein synthesis mechanisms (16 papers), RNA Research and Splicing (11 papers) and Bacterial Genetics and Biotechnology (9 papers). Larry J. Friedman is often cited by papers focused on RNA and protein synthesis mechanisms (16 papers), RNA Research and Splicing (11 papers) and Bacterial Genetics and Biotechnology (9 papers). Larry J. Friedman collaborates with scholars based in United States and United Kingdom. Larry J. Friedman's co-authors include Jeff Gelles, T. A. Dorschner, R. C. Sharp, D. P. Resler, Douglas S. Hobbs, Aaron A. Hoskins, Melissa J. Moore, Stephen P. Bell, Daniel J. Crawford and Hoang-Trung Nguyen and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Larry J. Friedman

50 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Optical phased array technology

1996 462 citations Larry J. Friedman et al. profile →

Peers

Larry J. Friedman

EEE

AMPO

EOMM

GENET

Mattias Goksör Sweden

Jens Michaelis Germany

Ajay Gopinathan United States

Stephen W. Turner United States

Ralf Seidel Germany

Peng‐Ye Wang China

Johann Engelhardt Germany

Samuel J. Lord United States

Paul R. Selvin United States

Kyu Young Han United States

Mattias Goksör Sweden

Larry J. Friedman

1.1k ×0.8

224 ×0.5

EEE

592 ×1.3

AMPO

170 ×0.6

EOMM

127 ×0.5

GENET

Citations per year, relative to Larry J. Friedman Larry J. Friedman (= 1×) peers Mattias Goksör

Countries citing papers authored by Larry J. Friedman

Since Specialization

Citations

This map shows the geographic impact of Larry J. Friedman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Larry J. Friedman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Larry J. Friedman more than expected).

Fields of papers citing papers by Larry J. Friedman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Larry J. Friedman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Larry J. Friedman. The network helps show where Larry J. Friedman may publish in the future.

Co-authorship network of co-authors of Larry J. Friedman

This figure shows the co-authorship network connecting the top 25 collaborators of Larry J. Friedman. A scholar is included among the top collaborators of Larry J. Friedman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Larry J. Friedman. Larry J. Friedman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Driscoll, D. D., Larry J. Friedman, Jeff Gelles, & Stephen P. Bell. (2025). An Orc6 tether mediates ORC binding-site switching during replication origin licensing. Proceedings of the National Academy of Sciences. 122(41). e2510685122–e2510685122.

Han, Liping, et al.. (2025). Mechanism of client loading from BiP to Grp94 and its disruption by select inhibitors. Nature Communications. 16(1). 3575–3575. 2 indexed citations

Jeon, Jongcheol, et al.. (2025). Single-molecule analysis of transcription activation: dynamics of SAGA coactivator recruitment. Nature Structural & Molecular Biology. 32(4). 675–686. 2 indexed citations

Friedman, Larry J., et al.. (2023). Recycling of bacterial RNA polymerase by the Swi2/Snf2 ATPase RapA. Proceedings of the National Academy of Sciences. 120(28). e2303849120–e2303849120. 9 indexed citations

Friedman, Larry J., et al.. (2023). RNA polymerase sliding on DNA can couple the transcription of nearby bacterial operons. Proceedings of the National Academy of Sciences. 120(30). e2301402120–e2301402120. 8 indexed citations

Friedman, Larry J., et al.. (2023). Changing protein–DNA interactions promote ORC binding-site exchange during replication origin licensing. Proceedings of the National Academy of Sciences. 120(30). e2305556120–e2305556120. 10 indexed citations

Gupta, Shalini, et al.. (2023). Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing. Proceedings of the National Academy of Sciences. 120(29). e2221484120–e2221484120. 10 indexed citations

Friedman, Larry J., et al.. (2021). DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7. eLife. 10. 22 indexed citations

Friedman, Larry J., et al.. (2021). Bayesian Classification and Modeling of Single Molecule Fluorescence Colocalization Images. Biophysical Journal. 120(3). 185a–185a. 1 indexed citations

10.

Friedman, Larry J., et al.. (2020). Dynamics of RNA polymerase II and elongation factor Spt4/5 recruitment during activator-dependent transcription. Proceedings of the National Academy of Sciences. 117(51). 32348–32357. 25 indexed citations

11.

Friedman, Larry J., et al.. (2019). A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding. eLife. 8. 25 indexed citations

12.

Huang, Bin, Larry J. Friedman, Ming Sun, Jeff Gelles, & Timothy O. Street. (2019). Conformational Cycling within the Closed State of Grp94, an Hsp90-Family Chaperone. Journal of Molecular Biology. 431(17). 3312–3323. 12 indexed citations

13.

Ticau, Simina, et al.. (2017). Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing. Nature Structural & Molecular Biology. 24(3). 309–315. 59 indexed citations

14.

Hoskins, Aaron A., Margaret L. Rodgers, Larry J. Friedman, Jeff Gelles, & Melissa J. Moore. (2016). Single molecule analysis reveals reversible and irreversible steps during spliceosome activation. eLife. 5. 37 indexed citations

15.

Ticau, Simina, Larry J. Friedman, Nikola A. Ivica, Jeff Gelles, & Stephen P. Bell. (2015). Single-Molecule Studies of Origin Licensing Reveal Mechanisms Ensuring Bidirectional Helicase Loading. Cell. 161(3). 513–525. 149 indexed citations

16.

MacKay, James F., et al.. (2014). Design and construction of a multiwavelength, micromirror total internal reflectance fluorescence microscope. Nature Protocols. 9(10). 2317–2328. 39 indexed citations

17.

Paramanathan, Thayaparan, Daniel Reeves, Larry J. Friedman, Jané Kondev, & Jeff Gelles. (2014). A general mechanism for competitor-induced dissociation of molecular complexes. Nature Communications. 5(1). 5207–5207. 37 indexed citations

18.

Friedman, Larry J., et al.. (2013). RNA polymerase approaches its promoter without long-range sliding along DNA. Proceedings of the National Academy of Sciences. 110(24). 9740–9745. 49 indexed citations

19.

Friedman, Larry J. & Jeff Gelles. (2012). Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation. Cell. 148(4). 679–689. 104 indexed citations

20.

Crawford, Daniel J., Aaron A. Hoskins, Larry J. Friedman, Jeff Gelles, & Melissa J. Moore. (2007). Visualizing the splicing of single pre-mRNA molecules in whole cell extract. RNA. 14(1). 170–179. 83 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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