Timothy M. Frayling

113.6k total citations · 5 hit papers
213 papers, 14.3k citations indexed

About

Timothy M. Frayling is a scholar working on Genetics, Molecular Biology and Surgery. According to data from OpenAlex, Timothy M. Frayling has authored 213 papers receiving a total of 14.3k indexed citations (citations by other indexed papers that have themselves been cited), including 135 papers in Genetics, 81 papers in Molecular Biology and 59 papers in Surgery. Recurrent topics in Timothy M. Frayling's work include Genetic Associations and Epidemiology (86 papers), Pancreatic function and diabetes (49 papers) and Diabetes and associated disorders (23 papers). Timothy M. Frayling is often cited by papers focused on Genetic Associations and Epidemiology (86 papers), Pancreatic function and diabetes (49 papers) and Diabetes and associated disorders (23 papers). Timothy M. Frayling collaborates with scholars based in United Kingdom, United States and Australia. Timothy M. Frayling's co-authors include Andrew T. Hattersley, Michael N. Weedon, Mark I. McCarthy, Andrew R. Wood, Joel N. Hirschhorn, Mark Walker, Jian Yang, G. A. Hitman, Peter M. Visscher and Sian Ellard and has published in prestigious journals such as The Lancet, Journal of Clinical Investigation and Nature Communications.

In The Last Decade

Timothy M. Frayling

209 papers receiving 14.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

2018 1.3k citations Andrew R. Wood, Michael N. Weedon et al. Human Molecular Genetics profile →
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

2012 736 citations Jian Yang, Michael N. Weedon et al. Nature Genetics profile →
Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes

2003 538 citations Michael N. Weedon, Bridget Knight et al. profile →
Biological interpretation of genome-wide association studies using predicted gene functions

2015 359 citations Tune H. Pers, Juha Karjalainen et al. Nature Communications profile →
Estimating sleep parameters using an accelerometer without sleep diary

2018 322 citations Vincent T. van Hees, Sèverine Sabia et al. Scientific Reports profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Timothy M. Frayling United Kingdom	65	7.1k	5.2k	3.2k	2.5k	1.8k	213	14.3k
Michael N. Weedon United Kingdom	56	6.1k 0.9×	3.5k 0.7×	2.8k 0.9×	2.5k 1.0×	1.2k 0.7×	182	11.4k
Daniel I. Chasman United States	59	4.3k 0.6×	4.1k 0.8×	2.2k 0.7×	1.6k 0.6×	1.2k 0.7×	185	12.5k
Michael A. Province United States	62	4.3k 0.6×	3.7k 0.7×	1.9k 0.6×	2.4k 1.0×	2.8k 1.6×	309	15.3k
Gibran Hemani United Kingdom	40	8.3k 1.2×	4.7k 0.9×	1.3k 0.4×	1.0k 0.4×	1.8k 1.0×	110	16.4k
Nicholas J. Timpson United Kingdom	62	9.3k 1.3×	5.2k 1.0×	2.0k 0.6×	2.0k 0.8×	3.2k 1.8×	250	22.6k
Franck Mauvais‐Jarvis United States	53	2.6k 0.4×	3.7k 0.7×	2.2k 0.7×	3.6k 1.4×	2.9k 1.6×	143	12.8k
Tom R. Gaunt United Kingdom	47	5.4k 0.8×	5.6k 1.1×	1.0k 0.3×	993 0.4×	1.5k 0.9×	200	13.8k
Wendy K. Chung United States	72	7.3k 1.0×	8.6k 1.6×	3.0k 0.9×	1.0k 0.4×	3.0k 1.7×	567	22.7k
Laura Almasy United States	67	6.3k 0.9×	4.9k 0.9×	981 0.3×	1.3k 0.5×	2.1k 1.2×	373	18.3k
Andrew R. Hoffman United States	76	3.1k 0.4×	7.5k 1.4×	2.0k 0.6×	6.0k 2.4×	3.8k 2.1×	343	18.3k

Countries citing papers authored by Timothy M. Frayling

Since Specialization

Citations

This map shows the geographic impact of Timothy M. Frayling's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy M. Frayling with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy M. Frayling more than expected).

Fields of papers citing papers by Timothy M. Frayling

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy M. Frayling. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy M. Frayling. The network helps show where Timothy M. Frayling may publish in the future.

Co-authorship network of co-authors of Timothy M. Frayling

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy M. Frayling. A scholar is included among the top collaborators of Timothy M. Frayling based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy M. Frayling. Timothy M. Frayling is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Chundru, V. Kartik, Leigh Jackson, Kashyap Patel, et al.. (2025). Whole-genome sequencing analysis identifies rare, large-effect noncoding variants and regulatory regions associated with circulating protein levels. Nature Genetics. 57(3). 626–634. 5 indexed citations

Green, Harry, Ji Chen, Jonathan P Evans, et al.. (2024). Hyperglycaemia is a causal risk factor for upper limb pathologies. International Journal of Epidemiology. 53(1). 2 indexed citations

Beaumont, Robin N., Jessica Tyrrell, Grace M. Power, et al.. (2023). Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood. Diabetologia. 66(8). 1472–1480. 5 indexed citations

Weedon, Michael N., Samuel E. Jones, Jacqueline M. Lane, et al.. (2022). The impact of Mendelian sleep and circadian genetic variants in a population setting. PLoS Genetics. 18(9). e1010356–e1010356. 4 indexed citations

Green, Harry, Jonathan P Evans, Andrew R. Wood, et al.. (2021). A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. PLoS Genetics. 17(6). e1009577–e1009577. 32 indexed citations

Thompson, William, Robin N. Beaumont, Alan Kuang, et al.. (2021). Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight. Human Molecular Genetics. 31(11). 1762–1775. 3 indexed citations

Thompson, William, Robin N. Beaumont, Alan Kuang, et al.. (2021). Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile. Diabetologia. 64(12). 2790–2802. 7 indexed citations

Howe, Laura D, Sean Harrison, Robin N. Beaumont, et al.. (2019). Effects of body mass index on relationship status, social contact and socio-economic position: Mendelian randomization and within-sibling study in UK Biobank. International Journal of Epidemiology. 49(4). 1173–1184. 37 indexed citations

Hees, Vincent T. van, Sèverine Sabia, Samuel E. Jones, et al.. (2018). Estimating sleep parameters using an accelerometer without sleep diary. Scientific Reports. 8(1). 12975–12975. 322 indexed citations breakdown →

10.

Pers, Tune H., Juha Karjalainen, Yingleong Chan, et al.. (2015). Biological interpretation of genome-wide association studies using predicted gene functions. Nature Communications. 6(1). 5890–5890. 359 indexed citations breakdown →

11.

Elliott, Hannah R., Therese Tillin, Nish Chaturvedi, et al.. (2013). DNA methylation, cardio metabolic risk and type 2 diabetes in south Asians and Europeans. Bristol Research (University of Bristol). 1 indexed citations

12.

Paternoster, Lavinia, Laura D Howe, Kate Tilling, et al.. (2011). Adult height variants affect birth length and growth rate in children. Human Molecular Genetics. 20(20). 4069–4075. 35 indexed citations

13.

Bell, Christopher G., Sarah Finer, Cecilia M. Lindgren, et al.. (2010). Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus. PLoS ONE. 5(11). e14040–e14040. 185 indexed citations

14.

Panicker, Vijay, Ponnusamy Saravanan, Bijay Vaidya, et al.. (2009). Common Variation in the DIO2 Gene Predicts Baseline Psychological Well-Being and Response to Combination Thyroxine Plus Triiodothyronine Therapy in Hypothyroid Patients. The Journal of Clinical Endocrinology & Metabolism. 94(5). 1623–1629. 238 indexed citations

15.

Shields, Beverley M., Rachel M. Freathy, Bridget Knight, et al.. (2009). Phosphodiesterase 8B Gene Polymorphism Is Associated with Subclinical Hypothyroidism in Pregnancy. The Journal of Clinical Endocrinology & Metabolism. 94(11). 4608–4612. 23 indexed citations

16.

Prokopenko, Inga, Pelin Akan, Hana Lango Allen, et al.. (2008). Fine-mapping type 2 diabetes causal variants on chromosome 9p21 in 2000 UK cases and 3000 unselected controls. Diabetologia. 51. 1 indexed citations

17.

Fernández‐Cadenas, Israel, Inga Prokopenko, Nicholas J. Timpson, et al.. (2008). Stratified analysis of the Wellcome Trust Case Control Consortium scan for type 2 diabetes reveals susceptibility loci that may affect age of diagnosis. Diabetologia. 51. 1 indexed citations

18.

Allen, Hana Lango, Michael N. Weedon, Nicholas J. Timpson, et al.. (2007). A common variant in the FTO gene region is associated with BMI in the general population and predisposes to adult and childhood obesity. Diabetologia. 50.

19.

Groves, Christopher J., Eleftheria Zeggini, Jon Minton, et al.. (2006). Large scale case-control and family-based analyses of TCF7L2 variants in > 6000 UK subjects demonstrates an almost two-fold difference in relative risk between homozygote classes. Diabetologia. 49. 14–14. 1 indexed citations

20.

Frayling, Timothy M., et al.. (2003). Combining Genome and Mouse Knockout Expression Data to Highlight Binding Sites for the Transcription Factor HNF1α. In Silico Biology. 3(1-2). 57–70. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact