Thomas Efferth

56.2k total citations · 9 hit papers
972 papers, 37.0k citations indexed

About

Thomas Efferth is a scholar working on Molecular Biology, Oncology and Pharmacology. According to data from OpenAlex, Thomas Efferth has authored 972 papers receiving a total of 37.0k indexed citations (citations by other indexed papers that have themselves been cited), including 532 papers in Molecular Biology, 234 papers in Oncology and 120 papers in Pharmacology. Recurrent topics in Thomas Efferth's work include Drug Transport and Resistance Mechanisms (135 papers), Natural product bioactivities and synthesis (99 papers) and Cancer therapeutics and mechanisms (89 papers). Thomas Efferth is often cited by papers focused on Drug Transport and Resistance Mechanisms (135 papers), Natural product bioactivities and synthesis (99 papers) and Cancer therapeutics and mechanisms (89 papers). Thomas Efferth collaborates with scholars based in Germany, China and Cameroon. Thomas Efferth's co-authors include Victor Kuete, M Volm, Yuangang Zu, Bernd Kaina, Mohamed E.M. Saeed, Onat Kadioglu, Ean‐Jeong Seo, V. Badireenath Konkimalla, Henry Johannes Greten and Franz Oesch and has published in prestigious journals such as Journal of Biological Chemistry, Angewandte Chemie International Edition and Nature Communications.

In The Last Decade

Thomas Efferth

944 papers receiving 36.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy

2017 480 citations Thomas Efferth profile →
The role of p53 in cancer drug resistance and targeted chemotherapy

2016 432 citations Thomas Efferth et al. profile →
Complex Interactions between Phytochemicals. The Multi-Target Therapeutic Concept of Phytotherapy

2010 411 citations Thomas Efferth et al. profile →
Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance

2020 391 citations Thomas Efferth et al. profile →
The Antiviral Activities of Artemisinin and Artesunate

2008 390 citations Thomas Efferth et al. profile →
Best practice in research – Overcoming common challenges in phytopharmacological research

2019 369 citations Thomas Efferth et al. Journal of Ethnopharmacology profile →
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells

2015 315 citations Onat Kadioglu, Thomas Efferth et al. Phytomedicine profile →
Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseases

2020 237 citations Thomas Efferth et al. profile →
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents

2023 96 citations Thomas Efferth et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thomas Efferth Germany	92	17.4k	6.4k	5.5k	4.8k	3.8k	972	37.0k
Amirhossein Sahebkar Iran	127	22.9k 1.3×	5.0k 0.8×	4.5k 0.8×	4.0k 0.8×	6.8k 1.8×	1.9k	69.4k
Chung S. Yang United States	114	15.5k 0.9×	5.1k 0.8×	3.2k 0.6×	5.9k 1.2×	3.8k 1.0×	524	44.9k
Hasan Mukhtar United States	114	14.6k 0.8×	4.2k 0.6×	4.0k 0.7×	3.1k 0.6×	4.1k 1.1×	557	41.3k
Peter J. Houghton United States	86	15.6k 0.9×	7.5k 1.2×	3.2k 0.6×	1.7k 0.4×	3.2k 0.8×	571	28.8k
Gautam Sethi Singapore	125	26.2k 1.5×	8.7k 1.3×	2.9k 0.5×	3.7k 0.8×	9.1k 2.4×	615	48.2k
John M. Pezzuto United States	84	16.7k 1.0×	2.1k 0.3×	6.5k 1.2×	3.0k 0.6×	2.1k 0.5×	528	32.0k
Carl Nathan United States	115	23.9k 1.4×	5.0k 0.8×	2.2k 0.4×	1.8k 0.4×	4.3k 1.1×	318	73.0k
Chi‐Tang Ho United States	108	18.2k 1.0×	2.0k 0.3×	11.2k 2.0×	4.2k 0.9×	2.1k 0.6×	1.2k	54.8k
Gordon M. Cragg United States	60	17.2k 1.0×	2.0k 0.3×	7.3k 1.3×	4.3k 0.9×	1.9k 0.5×	148	35.2k
Bharat B. Aggarwal United States	166	48.7k 2.8×	13.9k 2.2×	6.4k 1.2×	7.1k 1.5×	14.7k 3.9×	574	104.9k

Countries citing papers authored by Thomas Efferth

Since Specialization

Citations

This map shows the geographic impact of Thomas Efferth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas Efferth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas Efferth more than expected).

Fields of papers citing papers by Thomas Efferth

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas Efferth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas Efferth. The network helps show where Thomas Efferth may publish in the future.

Co-authorship network of co-authors of Thomas Efferth

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas Efferth. A scholar is included among the top collaborators of Thomas Efferth based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas Efferth. Thomas Efferth is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Hanxiao, et al.. (2025). Modulation of Pseudomonas aeruginosa-induced avoidance behavior by Shen Qi pills via mitogen-activated protein kinase PMK-1 and forkhead box protein O DAF-16 in Caenorhabditis elegans. Phytomedicine. 140. 156585–156585. 1 indexed citations

Abdelfatah, Sara, Christian Meesters, Kathrin Sutter, et al.. (2025). Diketopiperazine/piperidine alkaloid as a potential broad-spectrum coronaviral entry inhibitor identified by supercomputer-based virtual screening from a large natural product-based library. Biomedicine & Pharmacotherapy. 183. 117841–117841.

El‐Seedi, Hesham R., A. I. Sabry, Tariq Z. Abolibda, et al.. (2025). Unraveling the role of Globularia species in modern medicine based on evidence from photochemistry, traditional uses and biological activities. Phytomedicine. 139. 156466–156466. 1 indexed citations

Duan, Yongbo, Cheng Song, Shishu Huang, et al.. (2025). Inflammatory profiling and immune cell infiltration in dysthyroid optic neuropathy: insights from bulk RNA sequencing. Frontiers in Immunology. 16. 1550694–1550694. 1 indexed citations

Zhang, Wenwen, et al.. (2024). Paeoniflorin inhibited GSDMD to alleviate ANIT-induced cholestasis via pyroptosis signaling pathway. Phytomedicine. 134. 156021–156021. 9 indexed citations

Magalhães, Mariana, Joana Jorge, Ana Cristina Gonçalves, et al.. (2024). Unveiling the antitumor mechanism of 7α-acetoxy-6β-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma. Journal of Ethnopharmacology. 335. 118689–118689. 1 indexed citations

Mahmoud, Nuha, Mona Dawood, Mohamed Elbadawi, et al.. (2024). The cytotoxic activities of the major diterpene extracted from Salvia multicaulis (Bardakosh) are mediated by the regulation of heat-shock response and fatty acid metabolism pathways in human leukemia cells. Phytomedicine. 135. 156023–156023. 2 indexed citations

Tiwari, Onkar Nath, Md. Nazneen Bobby, Gopinath Halder, et al.. (2024). Comprehensive review on recent trends and perspectives of natural exo-polysaccharides: Pioneering nano-biotechnological tools. International Journal of Biological Macromolecules. 265(Pt 2). 130747–130747. 19 indexed citations

Rashan, Luay, et al.. (2024). Antidiabetic and antioxidant properties of Boswellia sacra oleo-gum in streptozotocin-induced diabetic rats. Journal of Ayurveda and Integrative Medicine. 15(4). 101014–101014. 2 indexed citations

10.

Goleij, Pouya, Pantea Majma Sanaye, Waqas Alam, et al.. (2024). Unlocking daidzein's healing power: Present applications and future possibilities in phytomedicine. Phytomedicine. 134. 155949–155949. 5 indexed citations

11.

Ma, Xiao, Qichao Hu, Tao Jiang, et al.. (2024). Dehydroevodiamine Alleviates Ulcerative Colitis by Inhibiting the PI3K/AKT/NF-κB Signaling Pathway via Targeting AKT1 and Regulating Gut Microbes and Serum Metabolism. Molecules. 29(17). 4031–4031. 6 indexed citations

12.

Lu, Xiaohua, Mingming Zhang, Huiling Xiong, et al.. (2024). Optimized therapeutic potential of Yinchenhao decoction for cholestatic hepatitis by combined network meta-analysis and network pharmacology. Phytomedicine. 129. 155573–155573. 15 indexed citations

13.

Li, Jun, Nasir Tajuddeen, Doris Feineis, et al.. (2023). Jozibrevine D from Ancistrocladus ileboensis, the fifth alkaloid in a series of six possible atropo-diastereomeric naphthylisoquinoline dimers, showing antiparasitic and antileukemic activities. Bioorganic & Medicinal Chemistry Letters. 86. 129258–129258.

14.

Liu, Huifan, Yuming Zhong, Gengsheng Xiao, et al.. (2021). Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p. Journal of Agricultural and Food Chemistry. 69(45). 13510–13523. 37 indexed citations

15.

Khalifa, Shaden A.M., Nermeen Yosri, Zhiming Guo, et al.. (2020). Screening for natural and derived bio-active compounds in preclinical and clinical studies: One of the frontlines of fighting the coronaviruses pandemic. Phytomedicine. 85. 153311–153311. 65 indexed citations

16.

To, Kenneth K.W., Xu Wu, Chun Yin, et al.. (2017). Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes. Journal of Ethnopharmacology. 203. 110–119. 42 indexed citations

17.

Theile, Dirk, Nahal Ketabi‐Kiyanvash, Christel Herold‐Mende, et al.. (2010). Evaluation of drug transporters' significance for multidrug resistance in head and neck squamous cell carcinoma. Head & Neck. 33(7). 959–968. 26 indexed citations

18.

Efferth, Thomas, Paul Thelen, Hans-Juergen Schulten, et al.. (2001). Differential expression of the multidrug resistance-related protein MRP1 in the histological compartments of nephroblastomas. International Journal of Oncology. 19(2). 367–71. 13 indexed citations

19.

Volm, M, et al.. (1993). Expression of resistance factors (P-glycoprotein, glutathione S-transferase-π, and topoisomerase II) and their interrelationship to proto-oncogene products in renal cell carcinomas. Cancer. 71(12). 3981–3987. 80 indexed citations

20.

Volm, M, Thomas Efferth, & J Mattern. (1993). Oncoprotein (c-myc, c-erbB1, c-erbB2, c-fos) and suppressor gene product (p53) expression in squamous cell carcinomas of the lung. Clinical and biological correlations. Lung Cancer. 8(5-6). 335–335. 78 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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