T. Ekblad

1.5k citations

17 papers · 1.2k indexed · h-index 15

Impact in

Oncology top 5%
- PARP inhibition in cancer therapy
Physiology top 5%

Papers in

Oncology 10
- PARP inhibition in cancer therapy 9
Immunology 7
- Toxin Mechanisms and Immunotoxins 7

Co-authors: H. Schüler T. Karlberg Antonio Macchiarulo A.G. Thorsell A.F. Pinto Johan Weigelt Michael S. Cohen M. Moche
Journals: Journal of Medicinal Chemistry (4 papers)European Journal of Nuclear Medicine and Molecular Imaging (2 papers)European Journal of Medicinal Chemistry (1 paper)SLAS DISCOVERY (1 paper)FEBS Journal (1 paper)
Partner nations: Sweden Canada Switzerland

In The Last Decade

T. Ekblad

17 papers receiving 1.2k citations

Peers

Countries citing papers authored by T. Ekblad

Since Specialization

Citations

This map shows the geographic impact of T. Ekblad's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by T. Ekblad with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites T. Ekblad more than expected).

Fields of papers citing papers by T. Ekblad

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by T. Ekblad. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by T. Ekblad. The network helps show where T. Ekblad may publish in the future.

Co-authorship network

The 25 scholars most cited alongside T. Ekblad, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with T. Ekblad Line = papers co-authored together T. Ekblad links everyone, so they are left out of the graph.

All Works

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17 of 17 papers shown

#	Work
1	Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol SLAS DISCOVERY ·T. Ekblad, Patricia Verheugd, Anders E. G. Lindgren, T. Nyman, Mikael Elofsson, H. Schüler	2018	22
2	Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors Journal of Medicinal Chemistry ·A.G. Thorsell, T. Ekblad, T. Karlberg, O. Okhrimenko, A.F. Pinto, L. Tresaugues, M. Moche, Michael S. Cohen, H. Schüler	2016	273
3	Towards small molecule inhibitors of mono-ADP-ribosyltransferases European Journal of Medicinal Chemistry ·T. Ekblad, Anders E. G. Lindgren, David Andersson, Rémi Caraballo, A.G. Thorsell, T. Karlberg, Marilyn Anaísza Guamán Chipantiza, Anna Linusson, H. Schüler, Mikael Elofsson	2015	43
4	Identification of Structure–Activity Relationships from Screening a Structurally Compact DNA‐Encoded Chemical Library Angewandte Chemie International Edition ·Raphael M. Franzini, T. Ekblad, Nan Zhong, Moreno Wichert, Willy Decurtins, H Yamauchi, Raj kumar Mishra, Florent Samain, Jörg Scheuermann, Peter J. Brown, Jonathan Hall, S. Gräslund, H. Schüler, Dario Neri	2015	82
5	Identification of Structure–Activity Relationships from Screening a Structurally Compact DNA‐Encoded Chemical Library Angewandte Chemie ·Raphael M. Franzini, T. Ekblad, Nan Zhong, Moreno Wichert, Willy Decurtins, H Yamauchi, Raj kumar Mishra, Florent Samain, Jörg Scheuermann, Peter J. Brown, Jonathan Hall, S. Gräslund, H. Schüler, Dario Neri	2015	14
6	Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres Chemical Biology & Drug Design ·T. Ekblad, H. Schüler	2015	16
7	Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library Journal of Medicinal Chemistry ·Florent Samain, T. Ekblad, Gediminas Mikutis, Nan Zhong, Raj kumar Mishra, H Yamauchi, Zhi-xiang Yu, Willy Decurtins, Jörg Scheuermann, Peter J. Brown, Jonathan Hall, S. Gräslund, H. Schüler, Dario Neri, Raphael M. Franzini	2015	55
8	Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3 Journal of Medicinal Chemistry ·Anders E. G. Lindgren, T. Karlberg, T. Ekblad, Marilyn Anaísza Guamán Chipantiza, A.G. Thorsell, David Andersson, Mamohlolo Eunice Chesa, Jacque Brumm, Johan Weigelt, Anna Linusson, H. Schüler, Mikael Elofsson	2013	11
9	PARP inhibitors: polypharmacology versus selective inhibition FEBS Journal ·T. Ekblad, Emidio Camaioni, H. Schüler, Antonio Macchiarulo	2013	65
10	PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3 ACS Chemical Biology ·Anders E. G. Lindgren, T. Karlberg, A.G. Thorsell, 陈昌芸, Marilyn Anaísza Guamán Chipantiza, T. Ekblad, David Andersson, A.F. Pinto, Johan Weigelt, Michael O. Hottiger, Anna Linusson, Mikael Elofsson, H. Schüler	2013	49
11	Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Nature Biotechnology ·E. Wahlberg, T. Karlberg, E. Kouznetsova, Natalia Markova, Antonio Macchiarulo, A.G. Thorsell, Ewa Pol, Åsa Frostell, T. Ekblad, Rochma Dwi Rahayu, Björn Kull, G.M. Robertson, Roberto Pellicciari, H. Schüler, Johan Weigelt	2012	382
12	Discovery of Ligands for ADP-Ribosyltransferases via Docking-Based Virtual Screening Journal of Medicinal Chemistry ·David Andersson, T. Karlberg, T. Ekblad, Anders E. G. Lindgren, A.G. Thorsell, Marilyn Anaísza Guamán Chipantiza, Urszula Uciechowska, Harry F. Bradford, Pernilla Wittung‐Stafshede, Johan Weigelt, Mikael Elofsson, H. Schüler, Anna Linusson	2012	35
13	186Re-maSGS-ZHER2:342, a potential Affibody conjugate for systemic therapy of HER2-expressing tumours European Journal of Nuclear Medicine and Molecular Imaging ·Anna Orlova, Thuy Tran, T. Ekblad, Amelie Eriksson Karlström, Vladimir Tolmachev	2009	36
14	Synthesis and chemoselective intramolecular crosslinking of a HER2‐binding affibody Biopolymers ·T. Ekblad, Vladimir Tolmachev, Anna Orlova, Christofer Lendel, Lars Abrahmsén, Amelie Eriksson Karlström	2009	14
15	Positioning of 99mTc-chelators influences radiolabeling, stability and biodistribution of Affibody molecules Bioorganic & Medicinal Chemistry Letters ·T. Ekblad, Anna Orlova, Joachim Feldwisch, Anders Wennborg, Amelie Eriksson Karlström, Vladimir Tolmachev	2009	14
16	Effects of Lysine-Containing Mercaptoacetyl-Based Chelators on the Biodistribution of ^99mTc-Labeled Anti-HER2 Affibody Molecules Bioconjugate Chemistry ·Thuy Tran, T. Ekblad, Anna Orlova, Mattias Sandström, Joachim Feldwisch, Anders Wennborg, Lars Abrahmsén, Vladimir Tolmachev, Amelie Eriksson Karlström	2008	42
17	Development and preclinical characterisation of 99mTc-labelled Affibody molecules with reduced renal uptake European Journal of Nuclear Medicine and Molecular Imaging ·T. Ekblad, Thuy Tran, Anna Orlova, Charles Widström, Joachim Feldwisch, Lars Abrahmsén, Anders Wennborg, Amelie Eriksson Karlström, Vladimir Tolmachev	2008	69

About T. Ekblad

T. Ekblad is a scholar working on Oncology, Immunology, Radiology, Nuclear Medicine and Imaging, Physiology and Molecular Biology, having authored 17 papers that have together received 1.2k indexed citations. Recurring topics across this work include PARP inhibition in cancer therapy (9 papers), Monoclonal and Polyclonal Antibodies Research (7 papers), Toxin Mechanisms and Immunotoxins (7 papers), Radiopharmaceutical Chemistry and Applications (4 papers), Chemical Synthesis and Analysis (3 papers), Electrostatic Discharge in Electronics (3 papers), Glycosylation and Glycoproteins Research (2 papers) and Cell death mechanisms and regulation (2 papers). The work is most often cited by research in Oncology (807 citations), Physiology (103 citations), Immunology (233 citations), Radiology, Nuclear Medicine and Imaging (238 citations) and Molecular Biology (685 citations). T. Ekblad has collaborated with scholars based in Sweden, Canada and Switzerland. Frequent co-authors include H. Schüler, T. Karlberg, Antonio Macchiarulo, A.G. Thorsell, A.F. Pinto, Johan Weigelt, A.G. Thorsell, Michael S. Cohen, M. Moche and L. Tresaugues. Their work appears in journals such as Journal of Medicinal Chemistry, European Journal of Nuclear Medicine and Molecular Imaging, European Journal of Medicinal Chemistry, SLAS DISCOVERY and FEBS Journal.

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