Butrus Atrash

2.0k citations

39 papers · 1.2k indexed · h-index 18

Molecular Biology top 10%
Oncology top 10%
Organic Chemistry top 10%
Cell Biology top 10%
Computational Theory and Mathematics top 5%

Co-authors: Michael Szelke Dylan M. Jones Julian Blagg B Leckie A. Hallett Anthony F. Lever Vassilios Bavetsias J.E. Sueiras
Topics: Microtubule and mitosis dynamics (12 papers)Chemical Synthesis and Analysis (11 papers)Cancer-related Molecular Pathways (6 papers)
Cited by: Oncology Molecular Biology Cell Biology
Journals: Nature Angewandte Chemie International Edition Blood
Partner nations: United Kingdom Switzerland United States

In The Last Decade

Butrus Atrash

39 papers receiving 1.2k citations

Peers

Countries citing papers authored by Butrus Atrash

Since Specialization

Citations

This map shows the geographic impact of Butrus Atrash's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Butrus Atrash with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Butrus Atrash more than expected).

Fields of papers citing papers by Butrus Atrash

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Butrus Atrash. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Butrus Atrash. The network helps show where Butrus Atrash may publish in the future.

Co-authorship network of co-authors of Butrus Atrash

This figure shows the co-authorship network connecting the top 25 collaborators of Butrus Atrash. A scholar is included among the top collaborators of Butrus Atrash based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Butrus Atrash. Butrus Atrash is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer 2020 ·PLoS ONE ·Sheelagh Frame,(unknown),Craig MacKay,Butrus Atrash,Peter Sheldrake,Edward McDonald,Paul A. Clarke,Paul Workman,David Blake,Daniella Zheleva	64
2	Metabolism of the dual FLT-3/Aurora kinase inhibitor CCT241736 in preclinical and human in vitro models: Implication for the choice of toxicology species 2019 ·European Journal of Pharmaceutical Sciences ·(unknown),(unknown),Angela Hayes,Manjuan Liu,(unknown),(unknown),Butrus Atrash,Amir Faisal,Vassilios Bavetsias,Spiros Linardopoulos,Julian Blagg,Florence I. Raynaud	4
3	Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitution 2016 ·Xenobiotica ·Angela Hayes,N. Yi Mok,Manjuan Liu,(unknown),Alan T. Henley,Butrus Atrash,Rachel M. Lanigan,(unknown),Yann‐Vaï Le Bihan,Vassilios Bavetsias,Julian Blagg,Florence I. Raynaud	4
4	7-(Pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine-based derivatives for kinase inhibition: Co-crystallisation studies with Aurora-A reveal distinct differences in the orientation of the pyrazole N1-substituent 2015 ·Bioorganic & Medicinal Chemistry Letters ·Vassilios Bavetsias,Yolanda Pérez-Fuertes,Patrick J. McIntyre,Butrus Atrash,Magda Kosmopoulou,(unknown),Rosemary Burke,Chongbo Sun,Amir Faisal,(unknown),(unknown),Alan T. Henley,Florence I. Raynaud,Spiros Linardopoulos,Richard Bayliss,Julian Blagg	13
5	Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns 2012 ·Leukemia ·Andrew S. Moore,Amir Faisal,David González de Castro,Vassilios Bavetsias,Chongbo Sun,Butrus Atrash,Melanie Valenti,(unknown),(unknown),(unknown),Fabio Mirabella,John Swansbury,Alex Pearson,Paul Workman,Julian Blagg,Florence I. Raynaud,Sue Eccles,Spiros Linardopoulos	90
6	The Aurora Kinase Inhibitor CCT137690 Downregulates MYCN and Sensitizes MYCN -Amplified Neuroblastoma In Vivo 2011 ·Molecular Cancer Therapeutics ·Amir Faisal,(unknown),Vassilios Bavetsias,Chongbo Sun,Butrus Atrash,(unknown),Yann Jamin,Simon P. Robinson,Paul Workman,Julian Blagg,Florence I. Raynaud,Suzanne A. Eccles,Louis Chesler,Spiros Linardopoulos	67
7	Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors 2011 ·Bioorganic & Medicinal Chemistry ·Stuart C. Wilson,Butrus Atrash,Clare Barlow,(unknown),Peter M. Fischer,Angela Hayes,Lloyd R. Kèlland,Wayne Jackson,Michael Jarman,Amin Mirza,Francisco J. Moreno,Bernard Nutley,Florence I. Raynaud,Peter Sheldrake,Mike Walton,Robert Westwood,Steven R. Whittaker,Paul Workman,Edward McDonald	26
8	Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells 2010 ·Bioorganic & Medicinal Chemistry Letters ·Nathalie Bouloc,Jonathan M. Large,Magda Kosmopoulou,Chongbo Sun,Amir Faisal,Mizio Matteucci,Jóhannes Reynisson,Nathan J. Brown,Butrus Atrash,Julian Blagg,Edward McDonald,Spiros Linardopoulos,Richard Bayliss,Vassilios Bavetsias	27
9	Dual Inhibition of Aurora and FLT3 Kinases by CCT137690: A Novel Treatment Strategy Against FLT3-ITD Positive AML In Vitro and In Vivo 2010 ·Blood ·Andrew S. Moore,Amir Faisal,Vassilios Bavetsias,Chongbo Sun,Butrus Atrash,Melanie Valenti,Alexis de Haven Brandon,(unknown),Florence I. Raynaud,Paul Workman,Andrew D.J. Pearson,Julian Blagg,Suzanne A. Eccles,Spiros Linardopoulos	3
10	Synthesis of resorcinylic macrocycles related to radicicol via ring-closing metathesis 2006 ·Tetrahedron Letters ·(unknown),Butrus Atrash,Peter Sheldrake,Paul Workman,Edward McDonald	13
11	Development of synthetic routes to macrocyclic compounds based on the HSP90 inhibitor radicicol 2006 ·Tetrahedron Letters ·Butrus Atrash,(unknown),Peter Sheldrake,Paul Workman,Edward McDonald	9
12	A new bio-compatible pH cleavable linker for solid-phase synthesis of a squalamine analogue 2001 ·Tetrahedron Letters ·(unknown),Butrus Atrash,Mark Bradley	12
13	Thrombin Inhibitors Based on Ketone Derivatives of Arginine and Lysine 1995 ·Journal of enzyme inhibition ·D. Michael Jones,Butrus Atrash,Hamish Ryder,Ann‐Catrine Teger‐Nilsson,(unknown),Michael Szelke	10
14	X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin 1993 ·Biochemical Journal ·David Bailey,J.B. Cooper,B. Veerapandian,T.L. Blundell,Butrus Atrash,Dylan M. Jones,Michael Szelke	42
15	On the rational design of renin inhibitors: x-ray studies of aspartic proteinases complexed with transition-state analogs 1987 ·Biochemistry ·T.L. Blundell,J.B. Cooper,S. Foundling,Dylan M. Jones,Butrus Atrash,Michael Szelke	82
16	Crystallographic Studies of Reduced Bond Inhibitors Complexed with an Aspartic Proteinase 1987 ·Journal of Cardiovascular Pharmacology ·S. I. Foundling,J.B. Cooper,(unknown),Laurence H. Pearl,Andrew M. Hemmings,S. P. Wood,T. Blundell,A. Hallett,Dylan M. Jones,J.E. Sueiras,Butrus Atrash,Michael Szelke	5
17	Renin inhibitors: their use in understanding the role of angiotensin II as a pressor hormone. 1985 ·PubMed ·M. Tree,Michael Szelke,B Leckie,Butrus Atrash,Brian T. Donovan,A. Hallett,Dylan M. Jones,Anthony F. Lever,J. J. Morton,Javier Sueiras-Diaz	4
18	Human renin inhibitors 1985 ·Biochemical Society Transactions ·B Leckie,Michael Szelke,Butrus Atrash,(unknown),Allan Hallett,D.M. Jones,Gordon D. McIntyre,(unknown),(unknown)	16
19	New Inhibitors of Human Renin Tested in vitro and in vivo in the Anaesthetized Baboon 1983 ·Journal of Hypertension ·M. Tree,Butrus Atrash,Brian T. Donovan,John F. Gamble,Allan Hallett,(unknown),D. Michael Jones,B Leckie,Anthony F. Lever,James J. Morton,Michael Szelke	20
20	Potent new inhibitors of human renin 1982 ·Nature ·Michael Szelke,B Leckie,A. Hallett,Dylan M. Jones,J.E. Sueiras,Butrus Atrash,Anthony F. Lever	183

About Butrus Atrash

Butrus Atrash is a scholar working on Cell Biology, Structural Biology and Oncology, having authored 39 papers that have together received 1.2k indexed citations. Recurring topics across this work include Microtubule and mitosis dynamics (12 papers), Chemical Synthesis and Analysis (11 papers) and Cancer-related Molecular Pathways (6 papers). The work is most often cited by research in Oncology (323 citations), Molecular Biology (767 citations) and Cell Biology (178 citations). Butrus Atrash has collaborated with scholars based in United Kingdom, Switzerland and United States. Frequent co-authors include Michael Szelke, Dylan M. Jones, Julian Blagg, B Leckie, A. Hallett, Anthony F. Lever, Vassilios Bavetsias, J.E. Sueiras, J.B. Cooper and Paul Workman. Their work appears in journals such as Nature, Angewandte Chemie International Edition and Blood.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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