Steven Henikoff

93.9k total citations · 23 hit papers
374 papers, 64.0k citations indexed

About

Steven Henikoff is a scholar working on Molecular Biology, Plant Science and Genetics. According to data from OpenAlex, Steven Henikoff has authored 374 papers receiving a total of 64.0k indexed citations (citations by other indexed papers that have themselves been cited), including 332 papers in Molecular Biology, 157 papers in Plant Science and 54 papers in Genetics. Recurrent topics in Steven Henikoff's work include Genomics and Chromatin Dynamics (184 papers), Chromosomal and Genetic Variations (131 papers) and RNA and protein synthesis mechanisms (75 papers). Steven Henikoff is often cited by papers focused on Genomics and Chromatin Dynamics (184 papers), Chromosomal and Genetic Variations (131 papers) and RNA and protein synthesis mechanisms (75 papers). Steven Henikoff collaborates with scholars based in United States, South Africa and France. Steven Henikoff's co-authors include Jorja G. Henikoff, Pauline C. Ng, Kami Ahmad, P. Naresh Kumar, Paul B. Talbert, Harmit S. Malik, Luca Comai, Peter J. Skene, Daniel Zilberman and Gabriel E. Zentner and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Steven Henikoff

370 papers receiving 62.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

2009 4.7k citations Steven Henikoff et al. profile →
Amino acid substitution matrices from protein blocks.

1992 4.4k citations Steven Henikoff, Jorja G. Henikoff Proceedings of the National Academy of Sciences profile →
Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 4.1k citations Steven Henikoff profile →
Predicting Deleterious Amino Acid Substitutions

2001 1.9k citations Steven Henikoff et al. Genome Research profile →
SIFT web server: predicting effects of amino acid substitutions on proteins

2012 1.6k citations Steven Henikoff et al. profile →
The epigenetic progenitor origin of human cancer

2005 1.3k citations Steven Henikoff et al. profile →
CUT&Tag for efficient epigenomic profiling of small samples and single cells

2019 1.2k citations Jorja G. Henikoff, Kami Ahmad et al. Nature Communications profile →
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription

2006 1.0k citations Daniel Zilberman, Mary Gehring et al. profile →
The Centromere Paradox: Stable Inheritance with Rapidly Evolving DNA

2001 986 citations Steven Henikoff, Kami Ahmad et al. Science profile →
An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

2017 981 citations Steven Henikoff et al. profile →
The Histone Variant H3.3 Marks Active Chromatin by Replication-Independent Nucleosome Assembly

2002 891 citations Kami Ahmad, Steven Henikoff Molecular Cell profile →
[12] Unidirectional digestion with exonuclease III in DNA sequence analysis

1987 868 citations Steven Henikoff Methods in enzymology on CD-ROM/Methods in enzymology profile →
Predicting the Effects of Amino Acid Substitutions on Protein Function

2006 727 citations Steven Henikoff et al. profile →
Requirement of CHROMOMETHYLASE3 for Maintenance of CpXpG Methylation

2001 719 citations Daniel Zilberman, Steven Henikoff et al. Science profile →
Regulation of nucleosome dynamics by histone modifications

2013 641 citations Gabriel E. Zentner, Steven Henikoff Nature Structural & Molecular Biology profile →
Unlocking the secrets of the genome

2009 609 citations Steven Henikoff et al. profile →
Consensus-degenerate hybrid oligonucleotide primers for amplification of distantly related sequences

1998 605 citations Steven Henikoff et al. profile →
Histone variants — ancient wrap artists of the epigenome

2010 588 citations Paul B. Talbert, Steven Henikoff profile →
TargetingInducedLocalLesionsIN Genomes (TILLING) for Plant Functional Genomics

2000 553 citations Steven Henikoff et al. profile →
Accounting for Human Polymorphisms Predicted to Affect Protein Function

2002 547 citations Steven Henikoff et al. Genome Research profile →
Doxorubicin, DNA torsion, and chromatin dynamics

2013 537 citations Steven Henikoff et al. profile →
Targeted in situ genome-wide profiling with high efficiency for low cell numbers

2018 471 citations Jorja G. Henikoff, Steven Henikoff et al. profile →
Efficient low-cost chromatin profiling with CUT&Tag

2020 235 citations Derek H. Janssens, Jorja G. Henikoff et al. profile →

Peers

Countries citing papers authored by Steven Henikoff

Since Specialization

Citations

This map shows the geographic impact of Steven Henikoff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven Henikoff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven Henikoff more than expected).

Fields of papers citing papers by Steven Henikoff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven Henikoff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven Henikoff. The network helps show where Steven Henikoff may publish in the future.

Co-authorship network of co-authors of Steven Henikoff

This figure shows the co-authorship network connecting the top 25 collaborators of Steven Henikoff. A scholar is included among the top collaborators of Steven Henikoff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven Henikoff. Steven Henikoff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Cell-cycle-dependent repression of histone gene transcription by histone H4 2026 ·Nature Structural & Molecular Biology ·(unknown), (unknown), (unknown), (unknown), (unknown), Steven Henikoff	0
2	Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag 2025 ·Molecular Cell ·Nadiya Khyzha, Kami Ahmad, Steven Henikoff	2
3	Protocol to measure centromeric array size changes using droplet digital PCR-based quantification of higher-order repeats 2024 ·STAR Protocols ·(unknown), Paul B. Talbert, (unknown), Steven Henikoff	1
4	Prediction of Therapeutic Potential of CD19 CAR-T Cells for LBCL By Histone Mark Analyses of Core Epigenetic Programming 2024 ·Blood ·(unknown), Yue Cao, Ye Zheng, Janaki Purushe, (unknown), Erik L. Kimble, Derek H. Janssens, (unknown), Alexandre V. Hirayama, Jordan Gauthier, David G. Maloney, Stanley R. Riddell, (unknown), Steven Henikoff, Jean Yang, Cameron J. Turtle	1
5	Aclarubicin stimulates RNA polymerase II elongation at closely spaced divergent promoters 2023 ·Science Advances ·Matthew Wooten, (unknown), Kami Ahmad, Steven Henikoff	8
6	Active enhancers strengthen insulation by RNA-mediated CTCF binding at chromatin domain boundaries 2023 ·Genome Research ·(unknown), (unknown), (unknown), (unknown), Anurag Kumar Singh, Radhakrishnan Sabarinathan, Jitendra Thakur, Awadhesh Pandit, Steven Henikoff, Dimple Notani	19
7	High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq) 2021 ·The Journal of Cell Biology ·Daniel A. Bartlett, Vishnu Dileep, Tetsuya Handa, Yasuyuki Ohkawa, Hiroshi Kimurâ, Steven Henikoff, David M. Gilbert	21
8	Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome 2020 ·Nature Communications ·He Fang, Giancarlo Bonora, Jordan P. Lewandowski, Jitendra Thakur, Galina N. Filippova, Steven Henikoff, Jay Shendure, Zhijun Duan, John L. Rinn, Xinxian Deng, William Stafford Noble, Christine M. Distèche	42
9	Non-B-Form DNA Is Enriched at Centromeres 2018 ·Molecular Biology and Evolution ·Sivakanthan Kasinathan, Steven Henikoff	113
10	Mediator binding to UAS s is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters 2016 ·The EMBO Journal ·Sebastian Grünberg, Steven Henikoff, Steven Hahn, Gabriel E. Zentner	50
11	Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones 2010 ·Science ·Roger B. Deal, Jorja G. Henikoff, Steven Henikoff	367
12	Extensive Demethylation of Repetitive Elements During Seed Development Underlies Gene Imprinting 2009 ·Science ·Mary Gehring, Kerry L. Bubb, Steven Henikoff	9
13	DNA demethylation in the Arabidopsis genome 2007 ·Proceedings of the National Academy of Sciences ·Jon Penterman, Daniel Zilberman, Jin Hoe Huh, Tracy Ballinger, Steven Henikoff, Robert L. Fischer	394
14	Histone Replacement Marks the Boundaries of cis-Regulatory Domains 2007 ·Science ·Yoshiko Mito, Jorja G. Henikoff, Steven Henikoff	210
15	Transcription and Histone Modifications in the Recombination-Free Region Spanning a Rice Centromere[W] 2005 ·The Plant Cell ·Huihuang Yan, Weiwei Jin, Kiyotaka Nagaki, Shulan Tian, Shu Ouyang, C. Robin Buell, Paul B. Talbert, Steven Henikoff, Jiming Jiang	91
16	Maize Centromeres: Organization and Functional Adaptation in the Genetic Background of Oat 2004 ·The Plant Cell ·Weiwei Jin, Juliana Melo, Kiyotaka Nagaki, Paul B. Talbert, Steven Henikoff, R. Kelly Dawe, Jiming Jiang	210
17	Histone H3.3 is enriched in covalent modifications associated with active chromatin 2004 ·Proceedings of the National Academy of Sciences ·(unknown), Philip R. Gafken, Kami Ahmad, Steven Henikoff	397
18	Amino acid substitution matrices 2000 ·Advances in protein chemistry ·Steven Henikoff, Jorja G. Henikoff	350
19	[6] Blocks database and its applications 1996 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Jorja G. Henikoff, Steven Henikoff	94
20	[7] Finding protein similarities with nucleotide sequence databases 1990 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Steven Henikoff, James C. Wallace, Joseph P. Brown	168

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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