Stephen B. Liggett

26.8k citations

261 papers · 19.5k indexed · 4 hit papers · h-index 75

Impact in

Cardiology and Cardiovascular Medicine top 0.2%
- Cardiac electrophysiology and arrhythmias
- Heart Failure Treatment and Management
Physiology top 0.1%
- Asthma and respiratory diseases
- Adipose Tissue and Metabolism

Papers in

Animal Science and Zoology 51
- Pharmacological Effects and Assays 51
Cellular and Molecular Neuroscience 68
- Neuropeptides and Animal Physiology 53

Co-authors: Gerald W. Dorn Kersten M. Small Margaret G. Eason Michael A. Innis J Turki Stuart A. Green Dennis W. McGraw John N. Lorenz
Journals: Journal of Biological Chemistry (26 papers)Proceedings of the National Academy of Sciences (19 papers)Journal of Clinical Investigation (12 papers)American Journal of Respiratory Cell and Molecular Biology (11 papers)Molecular Pharmacology (10 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

Stephen B. Liggett

258 papers receiving 19.0k citations

Hit Papers

align trajectories log scale

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction 2010 · 496 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Nature Medicine
2000 Proceedings of the National Academy of Sciences
1997 Proceedings of the National Academy of Sciences
1994 Biochemistry

Peers

Countries citing papers authored by Stephen B. Liggett

Since Specialization

Citations

This map shows the geographic impact of Stephen B. Liggett's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen B. Liggett with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen B. Liggett more than expected).

Fields of papers citing papers by Stephen B. Liggett

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen B. Liggett. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen B. Liggett. The network helps show where Stephen B. Liggett may publish in the future.

Co-authors

The 25 scholars most cited alongside Stephen B. Liggett, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Stephen B. Liggett Line = papers co-authored together Stephen B. Liggett links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Agonist activation to open the Gα subunit of the GPCR–G protein precoupled complex defines functional agonist activation of TAS2R5 Proceedings of the National Academy of Sciences ·Moon Young Yang, Khuong Duy Mac, Hannah R. Strzelinski, Sandy J. Hoffman, Donghwa Kim, Soo-Kyung Kim, Judith Su, Stephen B. Liggett, William A. Goddard	2024	1
2	A Par3/LIM Kinase/Cofilin Pathway Mediates Human Airway Smooth Muscle Relaxation by TAS2R14 American Journal of Respiratory Cell and Molecular Biology ·Jung A. Woo, Maria A. Castaño, Teresa R. Kee, Jordan Lee, Cynthia Koziol‐White, Steven S. An, Donghwa Kim, David E. Kang, Stephen B. Liggett	2023	7
3	Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy Journal of Biological Chemistry ·Sudarsan Rajan, Ganapathy Jagatheesan, Natalia Petrashevskaya, Brandon J. Biesiadecki, Chad M. Warren, Tara M. Riddle, Stephen B. Liggett, Beata M. Wolska, R. John Solaro, David F. Wieczorek	2018	13
4	Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via Gαi1,2,3 American Journal of Respiratory Cell and Molecular Biology ·Donghwa Kim, Jung A. Woo, Ezekiel A. Geffken, Steven S. An, Stephen B. Liggett	2017	54
5	Polymorphisms in human heat shock factor-1 and analysis of potential biological consequences Cell Stress and Chaperones ·Tiffany Bridges, R.G. Scheraga, Mohan E. Tulapurkar, Dante A. Suffredini, Stephen B. Liggett, Aparna Ramarathnam, Ratnakar Potla, Ishwar Singh, Jeffrey D. Hasday	2014	7
6	Prevention of Atrial Fibrillation by Bucindolol Is Dependent on the Beta 1 389 Arg/Gly Adrenergic Receptor Polymorphism JACC Heart Failure ·Ryan G. Aleong, William H. Sauer, Gordon Davis, Guinevere A. Murphy, J. David Port, Inder S. Anand, Mona Fiuzat, Christopher M. O’Connor, William T. Abraham, Stephen B. Liggett, Michael R. Bristow	2013	41
7	TAS2R activation promotes airway smooth muscle relaxation despite β ₂ -adrenergic receptor tachyphylaxis American Journal of Physiology-Lung Cellular and Molecular Physiology ·Steven S. An, Wayne C. H. Wang, Cynthia Koziol‐White, Kwangmi Ahn, Danielle Y. Lee, Richard C. Kurten, Reynold A. Panettieri, Stephen B. Liggett	2012	74
8	Sequencing and Analyses of All Known Human Rhinovirus Genomes Reveal Structure and Evolution Science ·Ann C. Palmenberg, David Spiro, Ryan Kuzmickas, Shiliang Wang, Appolinaire Djikeng, Jennifer A. Rathe, Claire M. Fraser, Stephen B. Liggett	2009	347
9	An internal domain of β-tropomyosin increases myofilament Ca²⁺sensitivity American Journal of Physiology-Heart and Circulatory Physiology ·Ganapathy Jagatheesan, Sudarsan Rajan, Emily Schulz, Rafeeq Ahmed, Natalia Petrashevskaya, Arnold Schwartz, Greg P. Boivin, Grace M. Arteaga, Tao Wang, Yi-Gang Wang, Muhammad Junaid Ashraf, Stephen B. Liggett, John N. Lorenz, R. John Solaro, David F. Wieczorek	2009	10
10	Transcriptional response to persistent β ₂ -adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility Physiological Genomics ·Dennis W. McGraw, Kevin M. Fogel, Sue Kong, Augusto A. Litonjua, Evangelia G. Kranias, Bruce J. Aronow, Stephen B. Liggett	2006	19
11	Polymorphisms of Adrenergic Receptors: Variations on a Theme Assay and Drug Development Technologies ·Stephen B. Liggett	2003	21
12	Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox Journal of Clinical Investigation ·Dennis W. McGraw, Khalid F. Almoosa, Richard J. Paul, Brian K. Kobilka, Stephen B. Liggett	2003	9
13	Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox Journal of Clinical Investigation ·Dennis W. McGraw, Khalid F. Almoosa, Richard J. Paul, Brian K. Kobilka, Stephen B. Liggett	2003	105
14	β2-Adrenergic Receptor Pharmacogenetics American Journal of Respiratory and Critical Care Medicine ·Stephen B. Liggett	2000	94
15	α2A/α2C-Adrenergic Receptor Third Loop Chimera Show That Agonist Interaction with Receptor Subtype Backbone Establishes G Protein-coupled Receptor Kinase Phosphorylation Journal of Biological Chemistry ·Elizabeth A. Jewell-Motz, Kersten M. Small, Cheryl T. Theiss, Stephen B. Liggett	2000	25
16	β2-Adrenergic Receptor Haplotypes in Mild, Moderate and Fatal/Near Fatal Asthma American Journal of Respiratory and Critical Care Medicine ·Tracey D. Weir, Noa Mallek, ANDREW J. SANDFORD, Tony R. Bai, NASSAR AWADH, J. Mark FitzGerald, Don Cockcroft, Anthony James, Stephen B. Liggett, Peter D. Paré	1998	149
17	Polymorphisms of the β2-Adrenergic Receptor and Asthma American Journal of Respiratory and Critical Care Medicine ·Stephen B. Liggett	1997	135
18	Sustained Activation of a G Protein-coupled Receptor via “Anchored” Agonist Binding Journal of Biological Chemistry ·Stuart A. Green, Andrew P. Spasoff, Robert A. Coleman, Malcolm Johnson, Stephen B. Liggett	1996	123
19	G-Protein Coupled Receptors, Nitric Oxide, and the IgE Receptor in Asthma American Journal of Respiratory and Critical Care Medicine ·Stephen B. Liggett, Roberto Levi, H Metzger	1995	3
20	Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor. PubMed ·William P. Hausdorff, Martin J. Lohse, Michel Bouvier, Stephen B. Liggett, M G Caron, R J Lefkowitz	1990	37

About Stephen B. Liggett

Stephen B. Liggett is a scholar working on Animal Science and Zoology, Cellular and Molecular Neuroscience, Sensory Systems, Physiology and Molecular Biology, having authored 261 papers that have together received 19.5k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (171 papers), Asthma and respiratory diseases (54 papers), Neuropeptides and Animal Physiology (53 papers), Pharmacological Effects and Assays (51 papers), Biochemical Analysis and Sensing Techniques (25 papers), Cardiac electrophysiology and arrhythmias (23 papers), Ion channel regulation and function (21 papers) and Adipose Tissue and Metabolism (19 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (5.6k citations), Physiology (5.8k citations), Animal Science and Zoology (2.1k citations), Sensory Systems (930 citations) and Cellular and Molecular Neuroscience (3.3k citations). Stephen B. Liggett has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Gerald W. Dorn, Kersten M. Small, Margaret G. Eason, Michael A. Innis, J Turki, Stuart A. Green, Dennis W. McGraw, John N. Lorenz, Richard A. Walsh and Lynne E. Wagoner. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Journal of Clinical Investigation, American Journal of Respiratory Cell and Molecular Biology and Molecular Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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