Sofie Symoens

6.4k citations

82 papers · 2.4k indexed · h-index 30

Impact in

Genetics top 1%
- Connective tissue disorders research
- Dermatological and Skeletal Disorders
Rheumatology top 2%
- Bone and Dental Protein Studies
- Dupuytren's Contracture and Treatments

Papers in ⓘ

Genetics 71
- Connective tissue disorders research 61
- Dermatological and Skeletal Disorders 15
Rheumatology 17
- Bone and Dental Protein Studies 10

Co-authors: Fransiska Malfait (50 shared papers)Anne De Paepe (33 shared papers)Paul Coucke (40 shared papers)Delfien Syx (26 shared papers)Bert Callewaert (15 shared papers)Trinh Hermanns‐Lê (6 shared papers)Julie De Backer (6 shared papers)Andy Willaert (12 shared papers)
Journals: Human Mutation (10 papers)Orphanet Journal of Rare Diseases (5 papers)Journal of Bone and Mineral Research (5 papers)Matrix Biology (4 papers)Genes (4 papers)
Partner nations: Belgium United States Netherlands

In The Last Decade

Sofie Symoens

79 papers receiving 2.4k citations

Peers

Countries citing papers authored by Sofie Symoens

Since Specialization

Citations

This map shows the geographic impact of Sofie Symoens's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sofie Symoens with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sofie Symoens more than expected).

Fields of papers citing papers by Sofie Symoens

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sofie Symoens. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sofie Symoens. The network helps show where Sofie Symoens may publish in the future.

Co-authors

The 25 scholars most cited alongside Sofie Symoens, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sofie Symoens Line = papers co-authored together Sofie Symoens links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 82 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes European Journal of Biochemistry ·Bart Christiaens, Sofie Symoens, Stefan Vanderheyden, Yves Engelborghs, Alain Joliot, Alain Prochiantz, Joël Vandekerckhove, Maryvonne Rosseneu, Berlinda Vanloo	2002	153
2	Comprehensive molecular analysis demonstrates type V collagen mutations in over 90% of patients with classic EDS and allows to refine diagnostic criteria Human Mutation ·Sofie Symoens, Delfien Syx, Fransiska Malfait, Bert Callewaert, Julie De Backer, Olivier Vanakker, Paul Coucke, Anne De Paepe	2012	129
3	Mutations in FKBP10 cause recessive osteogenesis imperfecta and bruck syndrome Journal of Bone and Mineral Research ·Brian Kelley, Fransiska Malfait, Luisa Bonafé, Dustin Baldridge, Erica P. Homan, Sofie Symoens, Andy Willaert, Nursel Elçioğlu, Lionel Van Maldergem, Christine Verellen‐Dumoulin, Y. Gillerot, Dobrawa Napierala, Deborah Krakow, Peter Beighton, Andrea Superti‐Furga, Anne De Paepe, Brendan Lee	2010	129
4	Three arginine to cysteine substitutions in the pro-alpha (I)-collagen chain cause Ehlers-Danlos syndrome with a propensity to arterial rupture in early adulthood Human Mutation ·Fransiska Malfait, Sofie Symoens, Julie De Backer, Trinh Hermanns‐Lê, Natzi Sakalihasan, Charles M. Lapière, Paul Coucke, Anne De Paepe	2007	102
5	Deficiency for the ER-stress transducer OASIS causes severe recessive osteogenesis imperfecta in humans Orphanet Journal of Rare Diseases ·Sofie Symoens, Fransiska Malfait, Sanne D’hondt, Bert Callewaert, Annelies Dheedene, Wouter Steyaert, Hans Peter Bächinger, Anne De Paepe, Hülya Kayserili, Paul Coucke	2013	98
6	Defective Initiation of Glycosaminoglycan Synthesis due to B3GALT6 Mutations Causes a Pleiotropic Ehlers-Danlos-Syndrome-like Connective Tissue Disorder The American Journal of Human Genetics ·Fransiska Malfait, Ariana Kariminejad, Tim Van Damme, Caroline Gauche, Delfien Syx, Faten Merhi‐Soussi, Sandrine Gulberti, Sofie Symoens, Suzanne Vanhauwaert, Andy Willaert, Bita Bozorgmehr, Mohamad Hasan Kariminejad, Nazanin Ebrahimiadib, Ingrid Haußer, Ann Huysseune, Sylvie Fournel‐Gigleux, Anne De Paepe	2013	98
7	The molecular basis of classic Ehlers-Danlos syndrome: A comprehensive study of biochemical and molecular findings in 48 unrelated patients Human Mutation ·Fransiska Malfait, Paul Coucke, Sofie Symoens, Bart Loeys, Lieve Nuytinck, Anne De Paepe	2004	95
8	EMQN best practice guidelines for the laboratory diagnosis of osteogenesis imperfecta European Journal of Human Genetics ·Fleur S van Dijk, Peter H. Byers, Raymond Dalgleish, Fransiska Malfait, Alessandra Maugeri, Marianne Rohrbach, Sofie Symoens, Erik A. Sistermans, Gerard Pals	2011	94
9	Musculocontractural Ehlers-Danlos Syndrome (former EDS type VIB) and adducted thumb clubfoot syndrome (ATCS) represent a single clinical entity caused by mutations in the dermatan-4-sulfotransferase 1 encoding CHST14 gene Human Mutation ·Fransiska Malfait, Delfien Syx, Philip Vlummens, Sofie Symoens, Sheela Nampoothiri, Trinh Hermanns‐Lê, Lut Van Laer, Anne De Paepe	2010	86
10	Zebrafish type I collagen mutants faithfully recapitulate human type I collagenopathies Proceedings of the National Academy of Sciences ·Charlotte Gistelinck, Ronald Y. Kwon, Fransiska Malfait, Sofie Symoens, Matthew P. Harris, Katrin Henke, M. Brent Hawkins, Shannon Fisher, Patrick Sips, Brecht Guillemyn, Jan Willem Bek, Petra Vermassen, Hanna De Saffel, P. Eckhard Witten, MaryAnn Weis, Anne De Paepe, David R. Eyre, Andy Willaert, Paul Coucke	2018	69
11	Recessive osteogenesis imperfecta caused by LEPRE1 mutations: clinical documentation and identification of the splice form responsible for prolyl 3-hydroxylation Journal of Medical Genetics ·Andy Willaert, Fransiska Malfait, Sofie Symoens, Kris Gevaert, Hülya Kayserili, André Mégarbané, Geert Mortier, JG Leroy, Paul Coucke, Anne De Paepe	2008	64
12	Genetic Heterogeneity and Clinical Variability in Musculocontractural Ehlers-Danlos Syndrome Caused by Impaired Dermatan Sulfate Biosynthesis Human Mutation ·Delfien Syx, Tim Van Damme, Sofie Symoens, Merel Maiburg, Ingrid M.B.H. van de Laar, Jenny Morton, Mohnish Suri, Miguel Del Campo, Ingrid Haußer, Trinh Hermanns‐Lê, Anne De Paepe, Fransiska Malfait	2015	63
13	Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome Orphanet Journal of Rare Diseases ·Fransiska Malfait, Sofie Symoens, Nathalie Goemans, Yolanda Gyftodimou, Eva Holmberg, Vanesa López‐González, Geert Mortier, Sheela Nampoothiri, Michael B. Petersen, Anne De Paepe	2013	62
14	Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model Matrix Biology ·Sanne D’hondt, Brecht Guillemyn, Delfien Syx, Sofie Symoens, Riet De Rycke, Leen Vanhoutte, Wendy Toussaint, Bart N. Lambrecht, Anne De Paepe, Douglas R. Keene, Yoshihiro Ishikawa, Hans Peter Bächinger, Sophie Janssens, Mathieu J.M. Bertrand, Fransiska Malfait	2018	53
15	Loss of Type I Collagen Telopeptide Lysyl Hydroxylation Causes Musculoskeletal Abnormalities in a Zebrafish Model of Bruck Syndrome Journal of Bone and Mineral Research ·Charlotte Gistelinck, P. Eckhard Witten, Ann Huysseune, Sofie Symoens, Fransiska Malfait, Daria Larionova, Pascal Simoens, Manuel Dierick, Luc Van Hoorebeke, Anne De Paepe, Ronald Y. Kwon, MaryAnn Weis, David R. Eyre, Andy Willaert, Paul Coucke	2016	53
16	COL5A1 signal peptide mutations interfere with protein secretion and cause classic Ehlers-Danlos syndrome Human Mutation ·Sofie Symoens, Fransiska Malfait, Marjolijn Renard, Josette André, Ingrid Haußer, Bart Loeys, Paul Coucke, Anne De Paepe	2008	51
17	Gene panel sequencing in heritable thoracic aortic disorders and related entities – results of comprehensive testing in a cohort of 264 patients Orphanet Journal of Rare Diseases ·Laurence Campens, Bert Callewaert, Laura Muiño Mosquera, Marjolijn Renard, Sofie Symoens, Anne De Paepe, Paul Coucke, Julie De Backer	2015	48
18	Osteogenesis imperfecta: the audiological phenotype lacks correlation with the genotype Orphanet Journal of Rare Diseases ·Freya Swinnen, Paul Coucke, Anne M. De Paepe, Sofie Symoens, Fransiska Malfait, Filomena Valentina Gentile, Luca Sangiorgi, P D’Eufemia, Mauro Celli, Ton Garretsen, Cor W. R. J. Cremers, Ingeborg Dhooge, Els De Leenheer	2011	45
19	Identification of binding partners interacting with the α1-N-propeptide of type V collagen Biochemical Journal ·Sofie Symoens, Marjolijn Renard, Christelle Bonod‐Bidaud, Delfien Syx, Elisabeth Vaganay, Fransiska Malfait, Sylvie Ricard‐Blum, Efrat Kessler, Lut Van Laer, Paul Coucke, Florence Ruggiero, Anne De Paepe	2010	44
20	Novel defects in collagen XII and VI expand the mixed myopathy/Ehlers–Danlos syndrome spectrum and lead to variant-specific alterations in the extracellular matrix Genetics in Medicine ·Sarah Delbaere, Tibbe Dhooge, Delfien Syx, Florence Petit, Nathalie Goemans, Anne Destrèe, Olivier Vanakker, Riet De Rycke, Sofie Symoens, Fransiska Malfait	2019	38

About Sofie Symoens

Sofie Symoens is a scholar working on Genetics, Rheumatology, Immunology and Allergy, Cell Biology and Cancer Research, having authored 82 papers that have together received 2.4k indexed citations. Recurring topics across this work include Connective tissue disorders research (61 papers), Dermatological and Skeletal Disorders (15 papers), Bone and Dental Protein Studies (10 papers), Protease and Inhibitor Mechanisms (10 papers), Ubiquitin and proteasome pathways (10 papers), Proteoglycans and glycosaminoglycans research (8 papers), Cell Adhesion Molecules Research (6 papers) and Skin and Cellular Biology Research (5 papers). The work is most often cited by research in Genetics (1.6k citations), Rheumatology (575 citations), Cell Biology (375 citations), Cancer Research (285 citations) and Immunology and Allergy (99 citations). Sofie Symoens has collaborated with scholars based in Belgium, United States and Netherlands. Frequent co-authors include Fransiska Malfait, Anne De Paepe, Paul Coucke, Delfien Syx, Bert Callewaert, Trinh Hermanns‐Lê, Julie De Backer, Andy Willaert, Sheela Nampoothiri and Bart Loeys. Their work appears in journals such as Human Mutation, Orphanet Journal of Rare Diseases, Journal of Bone and Mineral Research, Matrix Biology and Genes.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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