Simon W. M. John

21.2k citations

155 papers · 15.3k indexed · 4 hit papers · h-index 64

Impact in

Ophthalmology top 0.02%
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
Neurology top 0.1%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in

Ophthalmology 95
- Glaucoma and retinal disorders 91
- Retinal Diseases and Treatments 33
Neurology 20
- Neuroinflammation and Neurodegeneration Mechanisms 9

Co-authors: Richard T. Libby Richard S. Smith Gareth R. Howell Michael G. Anderson Oliver Smithies О. В. Савинова Douglas B. Gould Pete A. Williams
Journals: Investigative Ophthalmology & Visual Science (19 papers)BMC Genetics (7 papers)Proceedings of the National Academy of Sciences (6 papers)PLoS Genetics (5 papers)PLoS ONE (5 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

Simon W. M. John

151 papers receiving 15.0k citations

Hit Papers

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Vitamin B ₃ modulates mitochondrial vulnerability and prevents glaucoma in aged mice 2017 · 417 citations

Peers

Countries citing papers authored by Simon W. M. John

Since Specialization

Citations

This map shows the geographic impact of Simon W. M. John's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon W. M. John with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon W. M. John more than expected).

Fields of papers citing papers by Simon W. M. John

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon W. M. John. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon W. M. John. The network helps show where Simon W. M. John may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon W. M. John, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon W. M. John Line = papers co-authored together Simon W. M. John links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury Cell Death Discovery ·Marta Cabrero‐Hernández, Stephanie B. Syc‐Mazurek, Л.Н. Выгонская, Peter Shrager, Simon W. M. John, Richard T. Libby	2025	0
2	Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma eLife ·Yasunari Niiya, Nicholas Tolman, Ayellet V. Segrè, Kelsey V. Stuart, Oana A. Zeleznik, Neeru A. Vallabh, Kuang Hu, Nazlee Zebardast, Akiko Hanyuda, Yoshihiko Raita, Amanda de Souza Oliveira, Chi Zhang, Pirro G. Hysi, Ron Do, Anthony P. Khawaja, Janey L. Wiggs, Jae H. Kang, Simon W. M. John, Louis R. Pasquale	2025	2
3	Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states eLife ·Revathi Balasubramanian, Krishnakumar Kizhatil, Taibo Li, Nicholas Tolman, 暁明金, Graham Clark, Mika Yudistia, Ruth A. Kelly, Sarah R. Friedhoff, Lipskiĭ Li, Marina Simón, Amanda de Souza Oliveira, W. Daniel Stamer, Jiang Qian, Simon W. M. John	2024	5
4	Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology Human Molecular Genetics ·George Murray, Preeti Bais, Zhizhuo Zhang, Abigail L. D. Tadenev, Brian Hoffmann, Timothy J. Stodola, Kathryn H. Morelli, J�rg Arndt, David G. Schroeder, 민지영, Oliver Fiehn, Simon W. M. John, Carol J. Bult, Gregory A. Cox, Robert W. Burgess	2022	5
5	Genetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice Disease Models & Mechanisms ·Nicholas Tolman, Revathi Balasubramanian, Danilo G. Macalinao, Grace Annamal Gnana Piragasam, 花沢豊行, Amanda de Souza Oliveira, Wilhelmine N. de Vries, Ian J. Jackson, Sally H. Cross, Krishnakumar Kizhatil, K. Saidas Nair, Simon W. M. John	2021	17
6	Sympathetic Innervation of the Developing Aqueous Humor Drainage Structures Investigative Ophthalmology & Visual Science ·Krishnakumar Kizhatil, 克也長山, Graham Clark, Simon W. M. John	2018	2
7	Vitamin B ₃ modulates mitochondrial vulnerability and prevents glaucoma in aged mice Science ·Pete A. Williams, Jeffrey M. Harder, Nicole E. Foxworth, Kelly E. Cochran, Vivek M. Philip, Vittorio Porciatti, Oliver Smithies, Simon W. M. John Hit paper breakdown →	2017	417
8	The yin and yang of the complement cascade in glaucoma – the importance of timing and location Investigative Ophthalmology & Visual Science ·Gareth R. Howell, Pete A. Williams, Jeffrey M. Harder, James R. Tribble, A. Sai Hanuman, Stephen D. Cross, Paul Morgan, James P. Morgan, Simon W. M. John	2016	1
9	Nonvenous Origin of Dermal Lymphatic Vasculature Circulation Research ·Inés Martínez‐Corral, Maria H. Ulvmar, Lukas Stanczuk, Florence Tatin, Krishnakumar Kizhatil, Simon W. M. John, Kari Alitalo, Sagrario Ortega, Taija Mäkinen	2015	187
10	DBA/2J Mice Are Susceptible to Diabetic Nephropathy and Diabetic Exacerbation of IOP Elevation PLoS ONE ·Ileana Soto, Gareth R. Howell, E Nobuki Usuy, Hope R. Rutter, Richard T. Libby, Simon W. M. John	2014	17
11	Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma Journal of Clinical Investigation ·Gareth R. Howell, Danilo G. Macalinao, Gregory L. Sousa, Michael L. Walden, Ileana Soto, Stephen C. Kneeland, Daiva Plačenienė, Benjamin L. King, Jeffrey K. Marchant, Matthew Hibbs, Beth Stevens, Ben A. Barres, Abbot F. Clark, Richard T. Libby, Simon W. M. John	2011	364
12	Assessing Microglia/Macrophages in DBA/2J Glaucoma Investigative Ophthalmology & Visual Science ·Gareth R. Howell, Xianjun Zhu, Linda Van Eldik, Masako Ishikawa, Simon W. M. John	2010	2
13	Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection Progress in brain research ·Gareth R. Howell, Richard T. Libby, Simon W. M. John	2008	40
14	Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1 BMC Genetics ·Gareth R. Howell, Richard T. Libby, Jeffrey K. Marchant, Lawriston A. Wilson, Ioan M Cosma, Richard S. Smith, Michael G. Anderson, Simon W. M. John	2007	114
15	Mice With a Col4a1 Mutation Have Phenotypes Relevant to Human Age–Related Macular Degeneration Investigative Ophthalmology & Visual Science ·Douglas B. Gould, Richard T. Libby, Y Ichino, Richard S. Smith, Simon W. M. John	2006	1
16	Mutations in Col4a1 Cause Perinatal Cerebral Hemorrhage and Porencephaly Science ·Douglas B. Gould, 张久英, Guido J. Breedveld, Saskia E. van Mil, Richard S. Smith, John C. Schimenti, Umberto Aguglia, Marjo S. van der Knaap, Peter Heutink, Simon W. M. John	2005	366
17	Influence of Genetic Context on a Novel Mutation With Pleiotropic Phenotypes Including Ocular Dysgenesis, Glaucoma and Retinal Degeneration Investigative Ophthalmology & Visual Science ·Douglas B. Gould, 张久英, Ioan M Cosma, M.G. Menzheres, Richard T. Libby, Richard S. Smith, Simon W. M. John	2005	0
18	Anterior segment development relevant to glaucoma The International Journal of Developmental Biology ·Douglas B. Gould, Richard S. Smith, Simon W. M. John	2004	129
19	Characterization of the Zebrafish bug eye Mutation, Exploring a Genetic Model for Pressure-induced Retinal Cell Death Investigative Ophthalmology & Visual Science ·Simon W. M. John, Richard S. Smith, Brian D. Perkins, Matthew P. Gray, О. В. Савинова, John E. Dowling, K Skonieczna	2003	3
20	Deletion and Replacement of the Mouse Adult β-Globin Genes by a “Plug and Socket” Repeated Targeting Strategy Molecular and Cellular Biology ·Peter J. Detloff, Linnuel J. Pregil, Simon W. M. John, W. Ronald Shehee, Robert Langenbach, Nobuyo Maeda, Oliver Smithies	1994	50

About Simon W. M. John

Simon W. M. John is a scholar working on Ophthalmology, Neurology, Immunology and Allergy, Molecular Biology and Cell Biology, having authored 155 papers that have together received 15.3k indexed citations. Recurring topics across this work include Glaucoma and retinal disorders (91 papers), Retinal Development and Disorders (47 papers), Retinal Diseases and Treatments (33 papers), Corneal surgery and disorders (10 papers), Cell Adhesion Molecules Research (10 papers), Neuroinflammation and Neurodegeneration Mechanisms (9 papers), Connexins and lens biology (8 papers) and Photoreceptor and optogenetics research (7 papers). The work is most often cited by research in Ophthalmology (6.6k citations), Neurology (3.3k citations), Biological Psychiatry (367 citations), Developmental Neuroscience (542 citations) and Molecular Biology (7.6k citations). Simon W. M. John has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Richard T. Libby, Richard S. Smith, Gareth R. Howell, Michael G. Anderson, Oliver Smithies, О. В. Савинова, Douglas B. Gould, Pete A. Williams, Jeffrey M. Harder and Norman L. Hawes. Their work appears in journals such as Investigative Ophthalmology & Visual Science, BMC Genetics, Proceedings of the National Academy of Sciences, PLoS Genetics and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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