Siming Li

14.9k citations

122 papers · 6.1k indexed · 3 hit papers · h-index 35

Impact in

Cell Biology top 0.5%
- Hippo pathway signaling and YAP/TAZ
Aging top 1%

Papers in ⓘ

Co-authors: Jiandie D. Lin (29 shared papers)Xin Ye (1 shared paper)Arul M. Chinnaiyan (1 shared paper)Jianjun Yu (1 shared paper)Kun‐Liang Guan (1 shared paper)Li Li (1 shared paper)Bin Zhao (1 shared paper)Zhi-Chun Lai (1 shared paper)
Journals: Journal of Clinical Oncology (17 papers)Journal of Biological Chemistry (3 papers)International Immunopharmacology (3 papers)Cell Metabolism (2 papers)Clinical Cancer Research (2 papers)
Partner nations: China United States Ethiopia

In The Last Decade

Siming Li

117 papers receiving 6.0k citations

Hit Papers

align trajectories log scale

The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis 2014 · 386 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2014 Nature Medicine
2008 Genes & Development
2007 Nature

Peers

Countries citing papers authored by Siming Li

Since Specialization

Citations

This map shows the geographic impact of Siming Li's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Siming Li with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Siming Li more than expected).

Fields of papers citing papers by Siming Li

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Siming Li. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Siming Li. The network helps show where Siming Li may publish in the future.

Co-authors

The 25 scholars most cited alongside Siming Li, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Siming Li Line = papers co-authored together Siming Li links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 122 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	TEAD mediates YAP-dependent gene induction and growth control Genes & Development ·Bin Zhao, Xin Ye, Jindan Yu, Li Li, Weiquan Li, Siming Li, Jianjun Yu, Jiandie D. Lin, Cun-Yu Wang, Arul M. Chinnaiyan, Zhi-Chun Lai, Kun‐Liang Guan Hit paper breakdown →	2008	1934
2	Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism Nature ·Chang Liu, Siming Li, Tiecheng Liu, Jimo Borjigin, Jiandie D. Lin Hit paper breakdown →	2007	531
3	The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis Nature Medicine ·Guo-Xiao Wang, Xu-Yun Zhao, Zhuo‐Xian Meng, Matthias Kern, Arne Dietrich, Zhimin Chen, Zoharit Cozacov, Dequan Zhou, Adewole L. Okunade, Xiong Su, Siming Li, Matthias Blüher, Jiandie D. Lin Hit paper breakdown →	2014	386
4	Prevalence of BRAF V600E mutation in Chinese melanoma patients: Large scale analysis of BRAF and NRAS mutations in a 432-case cohort European Journal of Cancer ·Lu Si, Yan Kong, Xiaowei Xu, Keith T. Flaherty, Xinan Sheng, Chuanliang Cui, Zhihong Chi, Siming Li, Lili Mao, Jun Guo	2011	191
5	Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression Journal of Clinical Investigation ·Liang Guo, Peng Zhang, Zhimin Chen, Houjun Xia, Siming Li, Yanqiao Zhang, Sune Kobberup, Weiping Zou, Jiandie D. Lin	2017	141
6	Genome-wide Coactivation Analysis of PGC-1α Identifies BAF60a as a Regulator of Hepatic Lipid Metabolism Cell Metabolism ·Siming Li, Chang Liu, Na Li, Tong Hao, Ting Han, David E. Hill, Marc Vidal, Jiandie D. Lin	2008	139
7	Fibroblast growth factor 21 (FGF21) inhibits macrophage-mediated inflammation by activating Nrf2 and suppressing the NF-κB signaling pathway International Immunopharmacology ·Yin-Hang Yu, Jinjiao He, Siming Li, Liying Song, Xiaochen Guo, Wenbing Yao, Dehua Zou, Xinyu Gao, Yunye Liu, Fuliang Bai, Guiping Ren, Deshan Li	2016	135
8	Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis Nature Communications ·Xu-Yun Zhao, Xuelian Xiong, Tongyu Liu, Lin Mi, Xiaoling Peng, Crystal Rui, Liang Guo, Siming Li, (unknown), Jiandie D. Lin	2018	133
9	Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation Nature Medicine ·Zhuo‐Xian Meng, Siming Li, Lin Wang, Hwi Jin Ko, Yongjin Lee, Dae Young Jung, Mitsuharu Okutsu, Zhen Yan, Jason K. Kim, Jiandie D. Lin	2013	115
10	Increasing specificity in high-throughput yeast two-hybrid experiments Methods ·Pierre‐Olivier Vidalain, Mike Boxem, Hui Ming Ge, Siming Li, Marc Vidal	2004	110
11	Fibroblast growth factor 21 protects mouse brain against d-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation Pharmacology Biochemistry and Behavior ·Yin-Hang Yu, Fuliang Bai, Wenfei Wang, Yaonan Liu, Qingyan Yuan, Susu Qu, Tong Zhang, Guiyou Tian, Siming Li, Deshan Li, Guiping Ren	2015	100
12	Kinetics Study of Hydrogenation of Dimethyl Oxalate over Cu/SiO₂ Catalyst Industrial & Engineering Chemistry Research ·Siming Li, Yue Wang, Jian Zhang, Shengping Wang, Yan Xu, Yujun Zhao, Xinbin Ma	2015	93
13	Fibroblast growth factor (FGF21) protects mouse liver against d-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways Molecular and Cellular Biochemistry ·Yin-Hang Yu, Fuliang Bai, Yaonan Liu, Yongbi Yang, Qingyan Yuan, Dehua Zou, Susu Qu, Guiyou Tian, Liying Song, Tong Zhang, Siming Li, Yunye Liu, Wenfei Wang, Guiping Ren, Deshan Li	2015	88
14	A Phase II, Randomized, Double-blind, Placebo-controlled Multicenter Trial of Endostar in Patients With Metastatic Melanoma Molecular Therapy ·Chuanliang Cui, Lili Mao, Zhihong Chi, Lu Si, Xinan Sheng, Yan Kong, Siming Li, Bin Lian, Kangsheng Gu, Min Tao, Xin Song, Tongyu Lin, Xiubao Ren, Shukui Qin, Jun Guo	2013	83
15	KLF11 mediates PPARγ cerebrovascular protection in ischaemic stroke Brain ·Ke‐Jie Yin, Yanbo Fan, Michael R. Hamblin, Jifeng Zhang, Tainqing Zhu, Siming Li, John R. Hawse, Malayannan Subramaniam, Chao-Zhong Song, Raúl Urrutia, Jiandie D. Lin, Yanchao Chen	2013	80
16	Circadian autophagy rhythm: a link between clock and metabolism? Trends in Endocrinology and Metabolism ·Di Ma, Siming Li, Matthew M. Molusky, Jiandie D. Lin	2012	77
17	Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis Proceedings of the National Academy of Sciences ·Siming Li, Lin Mi, Lei Yu, Qi Yu, Tongyu Liu, Guo-Xiao Wang, Xu-Yun Zhao, Jun Wu, Jiandie D. Lin	2017	73
18	MAPK Pathway and TERT Promoter Gene Mutation Pattern and Its Prognostic Value in Melanoma Patients: A Retrospective Study of 2,793 Cases Clinical Cancer Research ·Xue Bai, Yan Kong, Zhihong Chi, Xinan Sheng, Chuanliang Cui, Xuan Wang, Lili Mao, Bixia Tang, Siming Li, Bin Lian, Xieqiao Yan, Li Zhou, Jie Dai, Jun Guo, Lu Si	2017	72
19	Neuronal Inactivation of Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Protects Mice from Diet-induced Obesity and Leads to Degenerative Lesions Journal of Biological Chemistry ·Di Ma, Siming Li, Elizabeth K. Lucas, Rita M. Cowell, Jiandie D. Lin	2010	68
20	Fibroblast growth factor 21 (FGF21) ameliorates collagen-induced arthritis through modulating oxidative stress and suppressing nuclear factor-kappa B pathway International Immunopharmacology ·Yin-Hang Yu, Siming Li, Yaonan Liu, Guiyou Tian, Qingyan Yuan, Fuliang Bai, Wenfei Wang, Zhiyi Zhang, Guiping Ren, Yu Zhang, Deshan Li	2015	66

About Siming Li

Siming Li is a scholar working on Aging, Endocrine and Autonomic Systems, Oncology, Molecular Biology and Immunology, having authored 122 papers that have together received 6.1k indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (14 papers), Adipose Tissue and Metabolism (14 papers), Fibroblast Growth Factor Research (13 papers), CAR-T cell therapy research (12 papers), Virus-based gene therapy research (10 papers), Cutaneous Melanoma Detection and Management (9 papers), Kruppel-like factors research (9 papers) and Epigenetics and DNA Methylation (8 papers). The work is most often cited by research in Cell Biology (2.0k citations), Aging (173 citations), Endocrine and Autonomic Systems (635 citations), Physiology (1.3k citations) and Molecular Biology (3.3k citations). Siming Li has collaborated with scholars based in China, United States and Ethiopia. Frequent co-authors include Jiandie D. Lin, Xin Ye, Arul M. Chinnaiyan, Jianjun Yu, Kun‐Liang Guan, Li Li, Bin Zhao, Zhi-Chun Lai, Jindan Yu and Weiquan Li. Their work appears in journals such as Journal of Clinical Oncology, Journal of Biological Chemistry, International Immunopharmacology, Cell Metabolism and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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