Silvia Paoletta

2.6k citations

42 papers · 1.6k indexed · h-index 23

Physiology top 0.2%
- Adenosine and Purinergic Signaling 32
Cellular and Molecular Neuroscience top 5%
- Neuropeptides and Animal Physiology 5
Molecular Biology top 10%
- Receptor Mechanisms and Signaling 29
- Pharmacological Receptor Mechanisms and Effects 16
- Chemical Synthesis and Analysis 6
Organic Chemistry top 5%
- Click Chemistry and Applications 8
- Synthesis and Biological Evaluation 3
Computational Theory and Mathematics top 5%
Toxicology
- Bioactive Compounds and Antitumor Agents 2

Co-authors: Kenneth A. Jacobson Zhan‐Guo Gao Qiang Zhao Raymond C. Stevens Vsevolod Katritch Beili Wu Stefano Moro Evgeny Kiselev
Cited by: Physiology Cellular and Molecular Neuroscience Molecular Biology
Journals: Journal of Medicinal Chemistry (8 papers)Bioorganic & Medicinal Chemistry (5 papers)ACS Medicinal Chemistry Letters (3 papers)
Partner nations: United States Italy Germany

In The Last Decade

Silvia Paoletta

42 papers receiving 1.6k citations

Peers

Countries citing papers authored by Silvia Paoletta

Since Specialization

Citations

This map shows the geographic impact of Silvia Paoletta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Silvia Paoletta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Silvia Paoletta more than expected).

Fields of papers citing papers by Silvia Paoletta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Silvia Paoletta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Silvia Paoletta. The network helps show where Silvia Paoletta may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Silvia Paoletta, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Silvia Paoletta Line = papers co-authored together Silvia Paoletta links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Inherited dysfunctional platelet P2Y12 receptor mutations associated with bleeding disorders Hämostaseologie ·Anna Lecchi,Eti Alessandra Femia,Silvia Paoletta,Arnaud Dupuis,Philippe Ohlmann,Christian Gachet,Kenneth A. Jacobson,Gian Marco Podda,Barbara Zieger,Marco Cattaneo,Katharina Machura	2016	17
2	Structure-Activity Analysis of Biased Agonism at the Human Adenosine A3 Receptor Molecular Pharmacology ·Jo‐Anne Baltos,Silvia Paoletta,Thi Nguyen,Karen J. Gregory,Dilip K. Tosh,Arthur Christopoulos,Kenneth A. Jacobson,Lauren T. May	2016	39
3	Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands Bioorganic & Medicinal Chemistry ·Jenny M. Vo-Phamhi,Silvia Paoletta,Evgeny Kiselev,Kenneth A. Jacobson	2015	25
4	Nucleotides Acting at P2Y Receptors: Connecting Structure and Function Molecular Pharmacology ·Kenneth A. Jacobson,Silvia Paoletta,Vsevolod Katritch,Beili Wu,Zhan‐Guo Gao,Qiang Zhao,Raymond C. Stevens,Evgeny Kiselev	2015	85
5	Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information Journal of Computer-Aided Molecular Design ·Silvia Paoletta,Davide Sabbadin,Ivar von Kügelgen,Sonja Hinz,Vsevolod Katritch,Kristina Hoffmann,Aliaa Abdelrahman,Amanda Leisoo,Younis Baqi,Qiang Zhao,Raymond C. Stevens,Stefano Moro,Christa E. Müller,Kenneth A. Jacobson	2015	43
6	Two disparate ligand-binding sites in the human P2Y1 receptor Nature ·Dandan Zhang,Zhan‐Guo Gao,Kaihua Zhang,Evgeny Kiselev,V. Costil,Jiang Wang,Silvia Paoletta,Cuiying Yi,Limin Ma,Wenru Zhang,Gye Won Han,Hong Liu,Vadim Cherezov,Vsevolod Katritch,Hualiang Jiang,Raymond C. Stevens,Kenneth A. Jacobson,Qiang Zhao,Beili Wu	2015	286
7	Structural Probing of Off-Target G Protein-Coupled Receptor Activities within a Series of Adenosine/Adenine Congeners PLoS ONE ·Silvia Paoletta,Dilip K. Tosh,Daniela Salvemini,Kenneth A. Jacobson	2014	20
8	Photomodulation of G Protein-Coupled Adenosine Receptors by a Novel Light-Switchable Ligand Bioconjugate Chemistry ·María Isabel Bahamonde,Jaume Taura,Silvia Paoletta,Andrei A. Gakh,Saibal Chakraborty,Jordi Hernando,Víctor Fernández‐Dueñas,Kenneth A. Jacobson,Pau Gorostiza,Francisco Ciruela	2014	39
9	Agonist-bound structure of the human P2Y12 receptor Nature ·Jin Zhang,Kaihua Zhang,Zhan‐Guo Gao,Silvia Paoletta,Dandan Zhang,Gye Won Han,Tingting Li,Limin Ma,Wenru Zhang,Christa E. Müller,Huaiyu Yang,Hualiang Jiang,Vadim Cherezov,Vsevolod Katritch,Kenneth A. Jacobson,Raymond C. Stevens,Beili Wu,Qiang Zhao	2014	264
10	Synthesis and evaluation of N6-substituted apioadenosines as potential adenosine A3 receptor modulators Bioorganic & Medicinal Chemistry ·Kiran S. Toti,Steven M. Moss,Silvia Paoletta,Zhan‐Guo Gao,Kenneth A. Jacobson,Serge Van Calenbergh	2014	5
11	John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y Receptors Computational and Structural Biotechnology Journal ·Kenneth A. Jacobson,Zhan‐Guo Gao,Silvia Paoletta,Evgeny Kiselev,Saibal Chakraborty,N el Wady,R. Balasubramanian,Dilip K. Tosh	2014	16
12	Computational studies to predict or explain G protein coupled receptor polypharmacology Trends in Pharmacological Sciences ·Kenneth A. Jacobson,Stefano Costanzi,Silvia Paoletta	2014	26
13	Discovery of novel A3 adenosine receptor ligands based on chromone scaffold Biochemical Pharmacology ·Alexandra Gaspar,Joana Reis,Sonja Kachler,Silvia Paoletta,Eugenio Uriarte,Karl‐Norbert Klotz,Stefano Moro,Fernanda Borges	2012	43
14	Fluorescent ligands for adenosine receptors Bioorganic & Medicinal Chemistry Letters ·Eszter Kozma,N el Wady,Lucia Squarcialupi,Silvia Paoletta,Stefano Moro,Stephanie Federico,Giampiero Spalluto,Kenneth A. Jacobson	2012	27
15	Structural Sweet Spot for A₁Adenosine Receptor Activation by Truncated (N)-Methanocarba Nucleosides: Receptor Docking and Potent Anticonvulsant Activity Journal of Medicinal Chemistry ·Dilip K. Tosh,Silvia Paoletta,Francesca Deflorian,Khai Phan,Steven M. Moss,Zhan‐Guo Gao,Xiaohui Jiang,Kenneth A. Jacobson	2012	35
16	Does the combination of optimal substitutions at the C2-, N5- and N8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 adenosine receptors? Bioorganic & Medicinal Chemistry ·Siew Lee Cheong,Anton V. Dolzhenko,Silvia Paoletta,蔡沁宏,Sonja Kachler,Stephanie Federico,Karl‐Norbert Klotz,Anna V. Dolzhenko,Giampiero Spalluto,Stefano Moro,Giorgia Pastorin	2011	12
17	A Novel Generalized 3D‐QSAR Model of Camptothecin Analogs Molecular Informatics ·Magdalena Bacilieri,Silvia Paoletta,Stefania Basili,Zechariah D. Emery,Stefano Moro	2011	2
18	Receptor-Driven Identification of Novel Human A3 Adenosine Receptor Antagonists as Potential Therapeutic Agents Methods in enzymology on CD-ROM/Methods in enzymology ·Silvia Paoletta,Stephanie Federico,Giampiero Spalluto,Stefano Moro	2010	7
19	Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand–receptor recognition process Bioorganic & Medicinal Chemistry ·Giorgia Pastorin,Stephanie Federico,Silvia Paoletta,Karl-Heinz Wobig,Francesca Cateni,Barbara Cacciari,Karl‐Norbert Klotz,Zhan‐Guo Gao,Kenneth A. Jacobson,Giampiero Spalluto,Stefano Moro	2010	27
20	Screening of herbal constituents for aromatase inhibitory activity Bioorganic & Medicinal Chemistry ·Silvia Paoletta,Glyn B. Steventon,Dirk Wildeboer,Thomas M. Ehrman,Peter J. Hylands,David J. Barlow	2008	37

About Silvia Paoletta

Silvia Paoletta is a scholar working on Physiology, Toxicology and Molecular Biology, having authored 42 papers that have together received 1.6k indexed citations. Recurring topics across this work include Adenosine and Purinergic Signaling (32 papers), Receptor Mechanisms and Signaling (29 papers), Pharmacological Receptor Mechanisms and Effects (16 papers), Click Chemistry and Applications (8 papers), Chemical Synthesis and Analysis (6 papers), Neuropeptides and Animal Physiology (5 papers), Synthesis and Biological Evaluation (3 papers) and Bioactive Compounds and Antitumor Agents (2 papers). The work is most often cited by research in Physiology (775 citations), Cellular and Molecular Neuroscience (440 citations) and Molecular Biology (1.1k citations). Silvia Paoletta has collaborated with scholars based in United States, Italy and Germany. Frequent co-authors include Kenneth A. Jacobson, Zhan‐Guo Gao, Qiang Zhao, Raymond C. Stevens, Vsevolod Katritch, Beili Wu, Stefano Moro, Evgeny Kiselev, Dilip K. Tosh and Kaihua Zhang. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of Chemical Information and Modeling and Bioorganic & Medicinal Chemistry Letters.

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