Seth B. Coffelt

11.3k citations

62 papers · 8.3k indexed · 4 hit papers · h-index 34

Impact in

Immunology top 0.2%
- Immune cells in cancer
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Oncology top 0.5%
- Cancer Immunotherapy and Biomarkers
- Cancer Cells and Metastasis

Papers in

Immunology 40
- Immune cells in cancer 22
- Immune Cell Function and Interaction 13
- T-cell and B-cell Immunology 9
- Immunotherapy and Immune Responses 7
Oncology 27
- Cancer Immunotherapy and Biomarkers 10
- Chemokine receptors and signaling 8

Co-authors: Karin E. de Visser Claire E. Lewis Max D. Wellenstein Craig Murdoch Munitta Muthana Cheei‐Sing Hau Kim Vrijland Aline B. Scandurro
Journals: Cancer Research (4 papers)Nature reviews. Cancer (3 papers)PLoS ONE (3 papers)Journal of Clinical Investigation (2 papers)Nature (2 papers)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

Seth B. Coffelt

59 papers receiving 8.2k citations

Hit Papers

align trajectories log scale

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis 2019 · 361 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Nature
2016 Nature reviews. Cancer
2015 Nature
2008 Nature reviews. Cancer

Peers

Countries citing papers authored by Seth B. Coffelt

Since Specialization

Citations

This map shows the geographic impact of Seth B. Coffelt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seth B. Coffelt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seth B. Coffelt more than expected).

Fields of papers citing papers by Seth B. Coffelt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seth B. Coffelt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seth B. Coffelt. The network helps show where Seth B. Coffelt may publish in the future.

Co-authors

The 25 scholars most cited alongside Seth B. Coffelt, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Seth B. Coffelt Line = papers co-authored together Seth B. Coffelt links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Partial Compensation of IL‐17 Production by Vγ1 T Cells in the Absence of Vγ4 and Vγ6 T Cells European Journal of Immunology ·Bonnie L. Rosenthal, 耕司添田, A. Davies, Ana Teresa B. O. Britto, Anika Janssen, Seth B. Coffelt, Immo Prinz, Inga Sandrock, Sarina Ravens	2025	0
2	Loss of DOCK2 potentiates Inflammatory Bowel Disease–associated colorectal cancer via immune dysfunction and IFNγ induction of IDO1 expression Oncogene ·A. M. D. Churchhouse, Karen Hagi, Toshiyasu Suzuki, Sebastian Pohl, S Sottolano, Kevin Donnelly, Colin Nixon, Mark J. Arends, Shahida Din, P. Ducroux, 和郎高山, Alex von Kriegsheim, Seth B. Coffelt, Kevin Myant	2024	2
3	Leukaemia Exposure Alters the Transcriptional Profile and Function of Macrophages in the Bone Marrow Niche Blood ·DavidC. Wildon, Kent M. Hoffman, Nichole Dopkins, Joana Bittencourt‐Silvestre, Zeng Xianlei, Giovanny Rodriguez Blanco, Mary T. Scott, Karen Dunn, Vaidehi Krishnan, Mhairi Copland, David Vetrie, Ravi Bhatia, Seth B. Coffelt, S. Tiong Ong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G. Vignir Helgason	2023	0
4	γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection Nature Communications ·Juan F. Quintana, Matthew C. Sinton, Soheyla Ahmadi Charkhabi, Lysander W. Babbitt, Ιωάννης Λιάμπας, Bachar Cheaib, O.Y. Kalinina, Dieudonné Mumba Ngoyi, Nono-Raymond Kuispond Swar, Anneli Cooper, Neil A. Mabbott, Seth B. Coffelt, Annette MacLeod	2023	10
5	PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells The Journal of Experimental Medicine ·Sarah C. Edwards, Ann Hedley, Bannikova Olga Anatolyevnaa, Tanaka Rikinobu, Ju-Lan Yang, Anna Kilbey, Robin Shaw, 齐绍武, Nizar N. Batada, Shinya Hatano, Yasunobu Yoshikai, Karen Blyth, Crispin Miller, Kristina Kirschner, Seth B. Coffelt	2022	35
6	The MSP‐RON axis stimulates cancer cell growth in models of triple negative breast cancer Molecular Oncology ·城ノ口秀樹, Anna Kilbey, Melissa K Bradley, Tesa Severson, Sandeep Dhayade, Emma Sandilands, Kyla Foster, David M. Bryant, Karen Blyth, Seth B. Coffelt	2020	12
7	Impact of Formate Supplementation on Body Weight and Plasma Amino Acids Nutrients ·Sandeep Dhayade, Matthias Pietzke, Tanaka Rikinobu, Jacqueline Tait-Mulder, Dimitris Athineos, David Sumpton, Seth B. Coffelt, Karen Blyth, Alexei Vázquez	2020	4
8	Emerging immunotherapies for metastasis British Journal of Cancer ·Sarah C. Edwards, Bannikova Olga Anatolyevnaa, Seth B. Coffelt	2020	40
9	Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response Nature Cell Biology ·Camilla Salvagno, Metamia Ciampricotti, Undre Ar, Cheei‐Sing Hau, Antoinette van Weverwijk, Seth B. Coffelt, Kelly Kersten, Kim Vrijland, Kevin Kos, Thomas Ulas, Ji‐Ying Song, Chia-Huey Ooi, Dominik Rüttinger, Philippe A. Cassier, Jos Jonkers, Joachim L. Schultze, Carola H. Ries, Karin E. de Visser	2019	122
10	Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages OncoImmunology ·Kelly Kersten, Seth B. Coffelt, Marlous Hoogstraat, Niels J. M. Verstegen, Kim Vrijland, Metamia Ciampricotti, Chris W. Doornebal, Cheei‐Sing Hau, Max D. Wellenstein, Camilla Salvagno, Parul Doshi, Esther H. Lips, Lodewyk F.A. Wessels, Karin E. de Visser	2017	85
11	CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity PMC ·Josephine Walton, Malcolm Farquharson, Susan Mason, Jennifer Port, Björn Kruspig, Suzanne Dowson, David Stevenson, Daniel J. Murphy, Martin M. Matzuk, Jaeyeon Kim, Seth B. Coffelt, Karen Blyth, Iain A. McNeish	2017	2
12	Immune-mediated mechanisms influencing the efficacy of anticancer therapies Trends in Immunology ·Seth B. Coffelt, Karin E. de Visser	2015	112
13	Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients Journal of Reproductive Immunology ·Ebtisam A. Al-ofi, Seth B. Coffelt, Dilly Anumba	2014	34
14	OS006. Functional expression of endogenous ligands of Toll like receptor4 on monocytes and placentae from women during normal pregnancy andpre-eclampsia Pregnancy Hypertension ·Ebtisam A. Al-ofi, Dilly Anumba, Seth B. Coffelt	2012	2
15	Monocyte Subpopulations from Pre-Eclamptic Patients Are Abnormally Skewed and Exhibit Exaggerated Responses to Toll-Like Receptor Ligands PLoS ONE ·Ebtisam A. Al-ofi, Seth B. Coffelt, Dilly Anumba	2012	38
16	Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors Cancer Research ·Munitta Muthana, Athina Giannoudis, Simon D. Scott, Hsin‐Yu Fang, Seth B. Coffelt, Martha Cruz‐Soto, Craig Murdoch, Julian Burton, Neil A. Cross, B. F. Burke, A. V. Tolochko, Freddie C. Hamdy, Nicola J. Brown, 余鑫炎, Peter Hoskin, Magnus Essand, Claire E. Lewis, Norman J. Maitland	2011	101
17	TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice Journal of Clinical Investigation ·Abigail Welford, Daniela Biziato, Seth B. Coffelt, Silvia Nucera, Matthew Fisher, Ferdinando Pucci, Clelia Di Serio, Luigi Naldini, Michele De Palma, Gillian M. Tozer, Claire E. Lewis	2011	186
18	Angiopoietin-2 Regulates Gene Expression in TIE2-Expressing Monocytes and Augments Their Inherent Proangiogenic Functions Cancer Research ·Seth B. Coffelt, Andrea O. Tal, Alexander Scholz, Michele De Palma, Sunil Patel, Carmen Urbich, Subhra K. Biswas, Craig Murdoch, Karl H. Plate, Yvonne Reiss, Claire E. Lewis	2010	268
19	Leucine Leucine-37 Uses Formyl Peptide Receptor–Like 1 to Activate Signal Transduction Pathways, Stimulate Oncogenic Gene Expression, and Enhance the Invasiveness of Ovarian Cancer Cells Molecular Cancer Research ·Seth B. Coffelt, Suzanne L. Tomchuck, Kevin J. Zwezdaryk, Elizabeth S. Danka, Aline B. Scandurro	2009	69
20	The role of myeloid cells in the promotion of tumour angiogenesis Nature reviews. Cancer ·Craig Murdoch, Munitta Muthana, Seth B. Coffelt, Claire E. Lewis Hit paper breakdown →	2008	1251

About Seth B. Coffelt

Seth B. Coffelt is a scholar working on Immunology, Oncology, Microbiology, Obstetrics and Gynecology and Reproductive Medicine, having authored 62 papers that have together received 8.3k indexed citations. Recurring topics across this work include Immune cells in cancer (22 papers), Immune Cell Function and Interaction (13 papers), Cancer Immunotherapy and Biomarkers (10 papers), T-cell and B-cell Immunology (9 papers), Chemokine receptors and signaling (8 papers), Immunotherapy and Immune Responses (7 papers), Antimicrobial Peptides and Activities (5 papers) and Angiogenesis and VEGF in Cancer (5 papers). The work is most often cited by research in Immunology (4.6k citations), Oncology (3.6k citations), Cancer Research (1.3k citations), Genetics (634 citations) and Microbiology (323 citations). Seth B. Coffelt has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Karin E. de Visser, Claire E. Lewis, Max D. Wellenstein, Craig Murdoch, Munitta Muthana, Cheei‐Sing Hau, Kim Vrijland, Aline B. Scandurro, Jos Jonkers and Metamia Ciampricotti. Their work appears in journals such as Cancer Research, Nature reviews. Cancer, PLoS ONE, Journal of Clinical Investigation and Nature.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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