Sergio E. Alvarez

2.6k total citations · 1 hit paper
31 papers, 2.2k citations indexed

About

Sergio E. Alvarez is a scholar working on Molecular Biology, Cell Biology and Immunology. According to data from OpenAlex, Sergio E. Alvarez has authored 31 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 7 papers in Cell Biology and 6 papers in Immunology. Recurrent topics in Sergio E. Alvarez's work include Sphingolipid Metabolism and Signaling (16 papers), Receptor Mechanisms and Signaling (4 papers) and Renin-Angiotensin System Studies (4 papers). Sergio E. Alvarez is often cited by papers focused on Sphingolipid Metabolism and Signaling (16 papers), Receptor Mechanisms and Signaling (4 papers) and Renin-Angiotensin System Studies (4 papers). Sergio E. Alvarez collaborates with scholars based in Argentina, United States and Slovakia. Sergio E. Alvarez's co-authors include Sarah Spiegel, Sheldon Milstien, Michael Maceyka, Nitai C. Hait, Tomasz Kordula, Kuzhuvelil B. Harikumar, Jeremy C. Allegood, Cheng Luo, Eugene Y. Kim and Hualiang Jiang and has published in prestigious journals such as Nature, SHILAP Revista de lepidopterología and Blood.

In The Last Decade

Sergio E. Alvarez

31 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

2010 615 citations Sergio E. Alvarez, Kuzhuvelil B. Harikumar et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sergio E. Alvarez Argentina	16	1.7k	614	574	280	150	31	2.2k
Keith Davidson United Kingdom	14	1.0k 0.6×	665 1.1×	385 0.7×	179 0.6×	67 0.4×	14	1.7k
Richard J. D’Andrea Australia	36	2.6k 1.6×	856 1.4×	780 1.4×	319 1.1×	270 1.8×	89	3.9k
Clark D. Wells United States	25	1.7k 1.0×	222 0.4×	910 1.6×	122 0.4×	132 0.9×	33	2.4k
Roy Katso United Kingdom	13	1.9k 1.1×	375 0.6×	466 0.8×	167 0.6×	206 1.4×	15	2.6k
Shunsuke Takasuga Japan	20	866 0.5×	317 0.5×	529 0.9×	185 0.7×	66 0.4×	37	1.5k
David A. Fruman United States	13	1.5k 0.9×	540 0.9×	409 0.7×	191 0.7×	141 0.9×	13	2.2k
Yun Fan United States	22	1.2k 0.7×	407 0.7×	466 0.8×	76 0.3×	131 0.9×	42	1.8k
Pat P. Ongusaha United States	17	1.5k 0.9×	337 0.5×	241 0.4×	155 0.6×	279 1.9×	20	2.0k
Koichi Miura Japan	23	1.4k 0.8×	215 0.4×	1.2k 2.1×	182 0.7×	120 0.8×	48	2.3k
Valentina Gandin Canada	21	1.9k 1.1×	247 0.4×	212 0.4×	226 0.8×	286 1.9×	31	2.3k

Countries citing papers authored by Sergio E. Alvarez

Since Specialization

Citations

This map shows the geographic impact of Sergio E. Alvarez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sergio E. Alvarez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sergio E. Alvarez more than expected).

Fields of papers citing papers by Sergio E. Alvarez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sergio E. Alvarez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sergio E. Alvarez. The network helps show where Sergio E. Alvarez may publish in the future.

Co-authorship network of co-authors of Sergio E. Alvarez

This figure shows the co-authorship network connecting the top 25 collaborators of Sergio E. Alvarez. A scholar is included among the top collaborators of Sergio E. Alvarez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sergio E. Alvarez. Sergio E. Alvarez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Angelina, Emilio, Sofı́a Salido, Lucas Gutiérrez, et al.. (2024). Second generation of pyrimidin-quinolone hybrids obtained from virtual screening acting as sphingosine kinase 1 inhibitors and potential anticancer agents. Bioorganic Chemistry. 144. 107112–107112. 2 indexed citations

Falcón, Cristian R., et al.. (2023). Melanoma cells with acquired resistance to vemurafenib have decreased autophagic flux and display enhanced ability to transfer resistance. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1869(7). 166801–166801. 4 indexed citations

Banchio, Claudia, et al.. (2023). Neurite outgrowth induced by stimulation of angiotensin II AT2 receptors in SH-SY5Y neuroblastoma cells involves c-Src activation. Heliyon. 9(5). e15656–e15656. 1 indexed citations

Garibotto, Francisco M., Emilio Angelina, Jiří Kos, et al.. (2019). Searching new structural scaffolds for BRAF inhibitors. An integrative study using theoretical and experimental techniques. Bioorganic Chemistry. 91. 103125–103125. 7 indexed citations

Lima, Santiago, Alirio Palma, Justo Cobo, et al.. (2019). Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti‐inflammatory activity. Archiv der Pharmazie. 352(3). e1800298–e1800298. 8 indexed citations

Castro, María G., et al.. (2017). In Vitro Methods to Study the Modulation of Migration and Invasion by Sphingosine-1-Phosphate. Methods in molecular biology. 1697. 117–131. 7 indexed citations

Angelina, Emilio, Santiago Lima, Tomáš Goněc, et al.. (2017). An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors. European Journal of Medicinal Chemistry. 139. 461–481. 32 indexed citations

Castro, María G., et al.. (2016). Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment. Frontiers in Oncology. 6. 218–218. 56 indexed citations

Price, Megan M., Carole A. Oskeritzian, Yves T. Falanga, et al.. (2012). A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma. Journal of Allergy and Clinical Immunology. 131(2). 501–511.e1. 130 indexed citations

10.

Alvarez, Sergio E., Kuzhuvelil B. Harikumar, Nitai C. Hait, et al.. (2010). Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature. 465(7301). 1084–1088. 615 indexed citations breakdown →

11.

Alvarez, Sergio E., et al.. (2008). Involvement of c‐Src tyrosine kinase in SHP‐1 phosphatase activation by Ang II AT₂receptors in rat fetal tissues. Journal of Cellular Biochemistry. 105(3). 703–711. 24 indexed citations

12.

Worrall, Dawn, Yun‐Kuan Liang, Sergio E. Alvarez, et al.. (2008). Involvement of sphingosine kinase in plant cell signalling. The Plant Journal. 56(1). 64–72. 101 indexed citations

13.

Valdivieso, Ángel G., et al.. (2007). The expression of the mitochondrial gene MT-ND4 is downregulated in cystic fibrosis. Biochemical and Biophysical Research Communications. 356(3). 805–809. 42 indexed citations

14.

Alvarez, Sergio E., Sheldon Milstien, & Sarah Spiegel. (2007). Autocrine and paracrine roles of sphingosine-1-phosphate. Trends in Endocrinology and Metabolism. 18(8). 300–307. 254 indexed citations

15.

Ayub, Maximiliano Juri, et al.. (2006). Production of recombinant enzymes of wide use for research. Electronic Journal of Biotechnology. 9(3). 0–0. 9 indexed citations

16.

Villarreal, Rodrigo, Sergio E. Alvarez, Maximiliano Juri Ayub, & Gladys M. Ciuffo. (2006). Angiotensin II modulates tyr-phosphorylation of IRS-4, an insulin receptor substrate, in rat liver membranes. Molecular and Cellular Biochemistry. 293(1-2). 35–46. 4 indexed citations

17.

Ayub, Maximiliano Juri, et al.. (2006). Production of recombinant enzymes of wide use for research. Electronic Journal of Biotechnology. 9(3). 0–0. 9 indexed citations

18.

Yu, JiaDe, et al.. (2006). Effects of N,N‐Dimethylsphingosine on Sphingosine Kinase. The FASEB Journal. 20(4). 1 indexed citations

19.

Alvarez, Sergio E., et al.. (2003). Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes. Molecular and Cellular Biochemistry. 254(1-2). 137–143. 5 indexed citations

20.

Ciuffo, Gladys M., et al.. (1998). Angiotensin II receptors induce tyrosine dephosphorylation in rat fetal membranes. Regulatory Peptides. 74(2-3). 129–135. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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