Sandra Afione

4.3k citations

62 papers · 3.4k indexed · h-index 27

Impact in

Genetics top 0.5%
- Virus-based gene therapy research
Molecular Biology top 5%
- RNA Interference and Gene Delivery
- CRISPR and Genetic Engineering
- Viral Infectious Diseases and Gene Expression in Insects

Papers in

Genetics 39
- Virus-based gene therapy research 37
Physiology 15
- Salivary Gland Disorders and Functions 13

Co-authors: Terence R. Flotte Pamela L. Zeitlin Rikki Solow William B. Guggino John A. Chiorini C. Conrad Michael Schmidt Barrie J. Carter
Journals: Journal of Virology (9 papers)Human Gene Therapy (4 papers)Gene Therapy (3 papers)Proceedings of the National Academy of Sciences (3 papers)Scientific Reports (2 papers)
Partner nations: United States Argentina Japan

In The Last Decade

Sandra Afione

61 papers receiving 3.3k citations

Peers

Countries citing papers authored by Sandra Afione

Since Specialization

Citations

This map shows the geographic impact of Sandra Afione's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sandra Afione with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sandra Afione more than expected).

Fields of papers citing papers by Sandra Afione

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sandra Afione. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sandra Afione. The network helps show where Sandra Afione may publish in the future.

Co-authors

The 25 scholars most cited alongside Sandra Afione, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sandra Afione Line = papers co-authored together Sandra Afione links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Amplified Type I Interferon Response in Sjögren's Disease via Ectopic Toll‐Like Receptor 7 Expression in Salivary Gland Epithelial Cells Induced by Lysosome‐Associated Membrane Protein 3 Arthritis & Rheumatology ·Hiroyuki Nakamura, Tsutomu Tanaka, Changyu Zheng, Sandra Afione, Tatsuya Atsumi, Masayuki Noguchi, Fabíola Reis de Oliveira, Ana Carolina Fragoso Motta, Fernando Chahud, Eduardo Melani Rocha, Blake M. Warner, John A. Chiorini	2024	7
2	Structural and antigenic characterization of the avian adeno-associated virus capsid Journal of Virology ·林之南, Mario Mietzsch, Paul R. Chipman, Sandra Afione, 仁胜刘, Rick Huang, John A. Chiorini, Robert McKenna	2023	10
3	Lysosome‐Associated Membrane Protein 3 Induces Lysosome‐Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease Arthritis & Rheumatology ·Hiroyuki Nakamura, Tsutomu Tanaka, Changyu Zheng, Sandra Afione, Blake M. Warner, Masayuki Noguchi, Tatsuya Atsumi, John A. Chiorini	2023	18
4	Association of G protein‐coupled receptor 78 with salivary dysfunction in male Sjögren's patients Oral Diseases ·Tsutomu Tanaka, Maria C. Guimaro, Hiroyuki Nakamura, Paola Pérez, Youngmi Ji, Drew G. Michael, Sandra Afione, Changyu Zheng, Corinne M. Goldsmith, William D. Swaim, Anne Marie Lynge Pedersen, John A. Chiorini	2023	3
5	Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy Scientific Reports ·Hiroyuki Nakamura, Tsutomu Tanaka, Changyu Zheng, Sandra Afione, Blake M. Warner, Masayuki Noguchi, Tatsuya Atsumi, John A. Chiorini	2022	11
6	Lysosome-associated membrane protein 3 misexpression in salivary glands induces a Sjögren's syndrome-like phenotype in mice Annals of the Rheumatic Diseases ·Hiroyuki Nakamura, Tsutomu Tanaka, Thomas Pranzatelli, Youngmi Ji, Hongen Yin, Paola Pérez, Sandra Afione, Shyh-Ing Jang, Rahni B. Kennedy, Chang Zheng, William D. Swaim, Blake M. Warner, Noriyuki Hirata, Masayuki Noguchi, Tatsuya Atsumi, John A. Chiorini	2021	26
7	Inhibition of bone morphogenetic protein 6 receptors ameliorates Sjögren’s syndrome in mice Scientific Reports ·Hongen Yin, Taras Hutsul, Zhennan Lai, Maria C. Guimaro, Bob Mehta, Blake M. Warner, Alberto Saibene, Nan Zhang, Javier Cabrera-Pérez, Hideyuki Kunishige, William D. Swaim, Sandra Afione, Kappelmayer Janos, Cuong Q. Nguyen, Paul B. Yu, Donald B. Bloch, John A. Chiorini	2020	17
8	Novel AAV44.9-Based Vectors Display Exceptional Characteristics for Retinal Gene Therapy Molecular Therapy ·Sanford L. Boye, Shreyasi Choudhury, Sean M. Crosson, Giovanni Di Pasquale, Sandra Afione, 장재욱, Sheila Gregory, Isabela Vitória Magri, Diego Fajardo, Jim Peterson, Hangning Zhang, عبد النبي عبد الله الطيب, O.M. Deneyev, John A. Chiorini, Ryan F. Boyd, (unknown), (unknown)	2020	24
9	Rescue of Adeno-Associated Virus Production by shRNA Cotransfection Human Gene Therapy ·Maria C. Guimaro, Sandra Afione, Tsutomu Tanaka, John A. Chiorini	2020	7
10	Hepatitis Delta Virus Detected in Salivary Glands of Sjögren’s Syndrome Patients and Recapitulates a Sjögren’s Syndrome-Like Phenotype in Vivo SHILAP Revista de lepidopterología ·Melodie L. Weller, Mutsumi Sawada, Feng Yan-yan, Michael A. Smith, Elisa Astorri, Drew G. Michael, Вадим Геджадзе, Changyu Zheng, Peter D. Burbelo, Zhennan Lai, P. A. Wilson, William D. Swaim, Beverly Handelman, Sandra Afione, Stefano Bombardieri, John A. Chiorini	2016	39
11	Assessment of the Safety and Biodistribution of a Regulated AAV2 Gene Transfer Vector after Delivery to Murine Submandibular Glands Toxicological Sciences ·Changyu Zheng, Antonis Voutetakis, Benjamin I. Goldstein, Sandra Afione, Victor M. Rivera, Tim Clackson, Martin L. Wenk, Daniel Riverin, Abraham Nyska, John A. Chiorini, Molly Vallant, Richard D. Irwin, Bruce J. Baum	2011	4
12	Evaluation of a rapamycin‐regulated serotype 2 adeno‐associated viral vector in macaque parotid glands Oral Diseases ·Changyu Zheng, Antonis Voutetakis, Mark E. Metzger, Sandra Afione, G. Hemalatha, Liu-Xiaoxing, Victor M. Rivera, Tim Clackson, JA Chiorini, RE Donahue, Cynthia E. Dunbar, 堅太郎辻	2010	1
13	Adeno‐associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human glioma The Journal of Gene Medicine ·Frits Thorsen, Sandra Afione, Peter C. Huszthy, Berit B. Tysnes, Agnete Svendsen, Rolf Bjerkvig, Robert M. Kotin, Per Eystein Lønning, Frank Hoover	2006	18
14	A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia Proceedings of the National Academy of Sciences ·Lynda S. Ostedgaard, Tatiana Rokhlina, Philip H. Karp, 富蔵小間, Sandra Afione, Michael Schmidt, Joseph Zabner, Mark F. Stinski, Weeraya Somana, Michael J. Welsh	2005	79
15	Effect of human vasoactive intestinal peptide gene transfer in a murine model of Sjögren's syndrome Annals of the Rheumatic Diseases ·Beatrijs M. Lodde, Fumi Mineshiba, Jianghua Wang, Ana P. Cotrim, Sandra Afione, Paul P. Tak, Bruce J. Baum	2005	84
16	Adeno-Associated Virus Vector Gene Expression Occurs in Nondividing Cells in the Absence of Vector DNA Integration American Journal of Respiratory Cell and Molecular Biology ·Terence R. Flotte, Sandra Afione, Pamela L. Zeitlin	1994	172
17	Gene Expression from Adeno-associated Virus Vectors in Airway Epithelial Cells American Journal of Respiratory Cell and Molecular Biology ·Terence R. Flotte, Rikki Solow, R. A. Owens, Sandra Afione, Pamela L. Zeitlin, Barrie J. Carter	1992	131
18	Possible role of vasoactive intestinal peptide in the hyperprolactinemia induced by ethanol Regulatory Peptides ·Adriana Seilicovich, B. Duvilanski, Luciano Debéljuk, Mercedes Lasaga, Daniel Pisera, Sandra Afione, Betty Claire Agree, Hanyin Guo	1991	3
19	Effects of serotonin on the hypothalamic-pituitary GABAergic system Brain Research Bulletin ·Sandra Afione, Beatriz H. Duvilanski, Adriana Seilicovich, Mercedes Lasaga, Meeting on Cell, Luciano Debéljuk	1990	6
20	Vasoactive intestinal peptide affects the GABAergic system in the hypothalamic-pituitary axis Brain Research Bulletin ·Beatriz H. Duvilanski, Mercedes Lasaga, Adriana Seilicovich, Sandra Afione, Meeting on Cell, Luciano Debéljuk	1990	7

About Sandra Afione

Sandra Afione is a scholar working on Genetics, Physiology, Behavioral Neuroscience, Cellular and Molecular Neuroscience and Molecular Biology, having authored 62 papers that have together received 3.4k indexed citations. Recurring topics across this work include Virus-based gene therapy research (37 papers), RNA Interference and Gene Delivery (17 papers), Viral Infectious Diseases and Gene Expression in Insects (15 papers), Salivary Gland Disorders and Functions (13 papers), Neuropeptides and Animal Physiology (8 papers), Respiratory viral infections research (7 papers), Viral gastroenteritis research and epidemiology (6 papers) and CAR-T cell therapy research (6 papers). The work is most often cited by research in Genetics (2.1k citations), Molecular Biology (1.9k citations), Infectious Diseases (465 citations), Pulmonary and Respiratory Medicine (613 citations) and Animal Science and Zoology (166 citations). Sandra Afione has collaborated with scholars based in United States, Argentina and Japan. Frequent co-authors include Terence R. Flotte, Pamela L. Zeitlin, Rikki Solow, William B. Guggino, John A. Chiorini, C. Conrad, Michael Schmidt, Barrie J. Carter, Robert M. Kotin and Marie E. Egan. Their work appears in journals such as Journal of Virology, Human Gene Therapy, Gene Therapy, Proceedings of the National Academy of Sciences and Scientific Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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