Samson T. Jacob

17.0k citations

195 papers · 11.0k indexed · 3 hit papers · h-index 51

Impact in

Cancer Research top 0.2%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
Molecular Biology top 0.5%
- Circular RNAs in diseases
- RNA modifications and cancer
- RNA Research and Splicing
- RNA and protein synthesis mechanisms
- Epigenetics and DNA Methylation
- RNA Interference and Gene Delivery

Papers in

Molecular Biology 160
- RNA Research and Splicing 49
- RNA and protein synthesis mechanisms 40
- RNA modifications and cancer 30
- Genomics and Chromatin Dynamics 17
- Epigenetics and DNA Methylation 16
Nutrition and Dietetics 25
- Trace Elements in Health 25

Co-authors: Kalpana Ghoshal Tushar Patel Kathleen M. Rose Roger Henson Fanyin Meng Hania Wehbe–Janek Sarmila Majumder Jharna Datta
Journals: Journal of Biological Chemistry (23 papers)Biochemical and Biophysical Research Communications (16 papers)Proceedings of the National Academy of Sciences (13 papers)Biochemistry (9 papers)Journal of Cellular Biochemistry (7 papers)
Partner nations: United States Germany Uganda

In The Last Decade

Samson T. Jacob

192 papers receiving 10.5k citations

Hit Papers

align trajectories log scale

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver 2012 · 623 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2012 Journal of Clinical Investigation
2008 Journal of Biological Chemistry
2007 Gastroenterology

Peers

Countries citing papers authored by Samson T. Jacob

Since Specialization

Citations

This map shows the geographic impact of Samson T. Jacob's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Samson T. Jacob with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Samson T. Jacob more than expected).

Fields of papers citing papers by Samson T. Jacob

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Samson T. Jacob. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Samson T. Jacob. The network helps show where Samson T. Jacob may publish in the future.

Co-authors

The 25 scholars most cited alongside Samson T. Jacob, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Samson T. Jacob Line = papers co-authored together Samson T. Jacob links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Ibrutinib Potentiates Antihepatocarcinogenic Efficacy of Sorafenib by Targeting EGFR in Tumor Cells and BTK in Immune Cells in the Stroma Molecular Cancer Therapeutics ·C.-H. Chen, Luan Feng, Nissar Ahmad Wani, Li Ding, Peng Hu, Juan M. Barajas, Lianbo Yu, Xiaoli Zhang, Samson T. Jacob, Wasif N. Khan, Xue‐Feng Bai, Anne M. Noonan, Kalpana Ghoshal	2019	27
2	Polyubiquitin Chains Linked by Lysine Residue 48 (K48) Selectively Target Oxidized Proteins In Vivo Antioxidants and Redox Signaling ·Damodar Sahu, Samson T. Jacob, Jade Wang, C. Johanson, Hiromi W.L. Koh, K. N. Kovalev, Hyungwon Choi, Christine Vogel, Gustavo M. Silva	2019	28
3	Reprogramming of Glucose Metabolism by Zerumbone Suppresses Hepatocarcinogenesis Molecular Cancer Research ·Nissar Ahmad Wani, Bo Zhang, Kun‐Yu Teng, Juan M. Barajas, Tasneem Motiwala, Ouwayda M. Raafat, Lianbo Yu, Rafael Brüschweiler, Kalpana Ghoshal, Samson T. Jacob	2018	32
4	Polyadenylation of SV40 late pre-mRNA is dependent on phosphorylation of an essential component associated with the 3′ end processing machinery Europe PMC (PubMed Central) ·Roger G. VonJouanne, Z Frankowski, Samson T. Jacob	2018	0
5	The sixth vital sign: HIV status assessment and severe illness triage in Uganda Public Health Action ·Matthew J. Cummings, Eric Goldberg, Srinivasan Sundarasan, 傅偉哲, Eric Vittinghoff, Achilles Katamba, Adithya Cattamanchi, Nathan Kenya‐Mugisha, J. Lucian Davis, Samson T. Jacob	2017	2
6	Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model Molecular Cancer Therapeutics ·Kun‐Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu‐Hao Hsu, Shun He, Nissar Ahmad Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu, Kalpana Ghoshal	2016	103
7	Reciprocal Regulation of MicroRNA-122 and c-Myc in Hepatocellular Cancer: Role of E2F1 and Transcription Factor Dimerization Partner 2 Hepatology ·Bo Wang, Shu‐Hao Hsu, Xinmei Wang, Huban Kutay, Hemant K. Bid, Jianhua Yu, Ramesh K. Ganju, Samson T. Jacob, Mariia Yuneva, Kalpana Ghoshal	2013	97
8	Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver Journal of Clinical Investigation ·Shu‐Hao Hsu, Bo Wang, Janaiah Kota, Jianhua Yu, Stefan Costinean, Huban Kutay, Lianbo Yu, Shoumei Bai, Krista La Perle, Raghu R. Chivukula, Hsiaoyin Mao, Wei Min, K. Reed Clark, Jerry R. Mendell, Michael A. Caligiuri, Samson T. Jacob, Joshua T. Mendell, Kalpana Ghoshal Hit paper breakdown →	2012	623
9	Reduced Susceptibility of DNA Methyltransferase 1 Hypomorphic (Dnmt1N/+) Mice to Hepatic Steatosis upon Feeding Liquid Alcohol Diet PLoS ONE ·Huban Kutay, Robert W. Hess, Bo Wang, Shu‐Hao Hsu, Jharna Datta, Lianbo Yu, Xiaoli Zhang, Sarmila Majumder, Tasneem Motiwala, Nuzhat Khan, Martha A. Belury, Craig J. McClain, Samson T. Jacob, Kalpana Ghoshal	2012	20
10	Lipid nanoparticles for hepatic delivery of small interfering RNA Biomaterials ·Bo Yu, Shu‐Hao Hsu, Chenguang Zhou, Xinmei Wang, A.G. Robertson, Yun Wu, Lesheng Teng, Yicheng Mao, Feng Wang, Weiming Xue, Samson T. Jacob, Kalpana Ghoshal, Robert J. Lee, Eliot Elisofon	2012	58
11	Metallothionein Expression Is Suppressed in Primary Human Hepatocellular Carcinomas and Is Mediated through Inactivation of CCAAT/Enhancer Binding Protein α by Phosphatidylinositol 3-Kinase Signaling Cascade Cancer Research ·Jharna Datta, Sarmila Majumder, Huban Kutay, Tasneem Motiwala, Wendy L. Frankel, Robert H. Costa, Anthony Spicci, Ormond A. MacDougald, Samson T. Jacob, Kalpana Ghoshal	2007	109
12	Role of Protein Tyrosine Phosphatases in Cancer Progress in nucleic acid research and molecular biology ·Tasneem Motiwala, Samson T. Jacob	2006	36
13	A Folate- and Methyl-Deficient Diet Alters the Expression of DNA Methyltransferases and Methyl CpG Binding Proteins Involved in Epigenetic Gene Silencing in Livers of F344 Rats Journal of Nutrition ·Kalpana Ghoshal, Xin Li, Jharna Datta, Shoumei Bai, Igor P. Pogribny, Guntur Prabowo, Yan Huang, Donn Young, Samson T. Jacob	2006	147
14	Molecular mechanism of decitabine -induced degradation of DNA methyltransferase 1 (DNMT1) in cancer cells Cancer Research ·Kalpana Ghoshal, Jharna Datta, Sarmila Majumder, Huban Kutay, Samson T. Jacob	2004	12
15	Analysis of Promoter Methylation and Its Role in Silencing Metallothionein I Gene Expression in Tumor Cells Methods in enzymology on CD-ROM/Methods in enzymology ·Kalpana Ghoshal, Sarmila Majumder, Samson T. Jacob	2002	17
16	Regulation of metallothionein gene expression Progress in nucleic acid research and molecular biology ·Kalpana Ghoshal, Samson T. Jacob	2000	109
17	Ara-ATP impairs 3′-end processing of pre-mRNAs by inhibiting both cleavage and polyadenylation Nucleic Acids Research ·Kalpana Ghoshal, Samson T. Jacob	1991	10
18	A cis -Acting Sequence within the Rat Ribosomal DNA Enhancer Region Can Modulate RNA Polymerase II-Directed Transcription of the Metallothionein I Gene In Vitro DNA ·Aparna Dixit, Lalit C. Garg, Samson T. Jacob	1989	9
19	Specific inhibition of chromatin-associated poly(A) synthesis in vitro by cordycepin 5′-triphosphate Nature ·Kathleen M. Rose, Linn E. Bell, Samson T. Jacob	1977	66
20	Biological Sciences: Specific Action of α-Amanitin on Mammalian RNA Polymerase Protein Nature ·Samson T. Jacob, Elizabeth M. Sajdel, Hamish N. Munro	1970	114

About Samson T. Jacob

Samson T. Jacob is a scholar working on Molecular Biology, Nutrition and Dietetics, Cancer Research, Toxicology and Immunology, having authored 195 papers that have together received 11.0k indexed citations. Recurring topics across this work include RNA Research and Splicing (49 papers), RNA and protein synthesis mechanisms (40 papers), RNA modifications and cancer (30 papers), Trace Elements in Health (25 papers), Genomics and Chromatin Dynamics (17 papers), Epigenetics and DNA Methylation (16 papers), MicroRNA in disease regulation (14 papers) and Cancer-related molecular mechanisms research (12 papers). The work is most often cited by research in Cancer Research (4.0k citations), Molecular Biology (8.2k citations), Hepatology (371 citations), Immunology (952 citations) and Nutrition and Dietetics (672 citations). Samson T. Jacob has collaborated with scholars based in United States, Germany and Uganda. Frequent co-authors include Kalpana Ghoshal, Tushar Patel, Kathleen M. Rose, Roger Henson, Fanyin Meng, Hania Wehbe–Janek, Sarmila Majumder, Jharna Datta, Elizabeth M. Sajdel and Bo Wang. Their work appears in journals such as Journal of Biological Chemistry, Biochemical and Biophysical Research Communications, Proceedings of the National Academy of Sciences, Biochemistry and Journal of Cellular Biochemistry.

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