Sam D. Groombridge

611 total citations
17 papers, 299 citations indexed

About

Sam D. Groombridge is a scholar working on Molecular Biology, Organic Chemistry and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, Sam D. Groombridge has authored 17 papers receiving a total of 299 indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Molecular Biology, 6 papers in Organic Chemistry and 6 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in Sam D. Groombridge's work include Receptor Mechanisms and Signaling (5 papers), Neuropeptides and Animal Physiology (5 papers) and Diabetes Treatment and Management (3 papers). Sam D. Groombridge is often cited by papers focused on Receptor Mechanisms and Signaling (5 papers), Neuropeptides and Animal Physiology (5 papers) and Diabetes Treatment and Management (3 papers). Sam D. Groombridge collaborates with scholars based in United Kingdom, Sweden and Brazil. Sam D. Groombridge's co-authors include Andrew G. Leach, James S. Scott, Alan M. Birch, Robert V. Law, Graeme R. Robb, Philip A. MacFaul, Frederick W. Goldberg, Darren McKerrecher, Pablo Morentin Gutierrez and Kristin Goldberg and has published in prestigious journals such as PLoS ONE, Journal of Medicinal Chemistry and Tetrahedron Letters.

In The Last Decade

Sam D. Groombridge

16 papers receiving 294 citations

Peers

Countries citing papers authored by Sam D. Groombridge

Since Specialization

Citations

This map shows the geographic impact of Sam D. Groombridge's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sam D. Groombridge with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sam D. Groombridge more than expected).

Fields of papers citing papers by Sam D. Groombridge

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sam D. Groombridge. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sam D. Groombridge. The network helps show where Sam D. Groombridge may publish in the future.

Co-authorship network of co-authors of Sam D. Groombridge

This figure shows the co-authorship network connecting the top 25 collaborators of Sam D. Groombridge. A scholar is included among the top collaborators of Sam D. Groombridge based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sam D. Groombridge. Sam D. Groombridge is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

#	Work	Indexed citations
1	Identification and optimisation of a pyrimidopyridone series of IRAK4 inhibitors 2022 ·Bioorganic & Medicinal Chemistry ·Iain Cumming, Sébastien L. Degorce, Anna Aagaard, (unknown), Nichola L. Davies, C. R. Diène, Andrew J. Eatherton, (unknown), Sam D. Groombridge, Eva M. Lenz, Yunxia Li, (unknown), Stuart E. Pearson, Graeme R. Robb, James S. Scott, (unknown), (unknown), Yafeng Xue, Lanping Zhang, (unknown)	4
2	Tricyclic Indazoles—A Novel Class of Selective Estrogen Receptor Degrader Antagonists 2019 ·Journal of Medicinal Chemistry ·James S. Scott, Andrew Bailey, David Buttar, Rodrigo J. Carbajo, Jon Curwen, Paul R. J. Davey, Robert D. M. Davies, Sébastien L. Degorce, Craig S. Donald, Eric T. Gangl, Ryan Greenwood, Sam D. Groombridge, Tony Johnson, Scott G. Lamont, Mandy Lawson, (unknown), Christopher J. Morrow, Tom Moss, Jennifer H. Pink, Radosław Polański	26
3	Optimization of permeability in a series of pyrrolotriazine inhibitors of IRAK4 2018 ·Bioorganic & Medicinal Chemistry ·Sébastien L. Degorce, Rana Anjum, Keith Dillman, Lisa Drew, Sam D. Groombridge, (unknown), Eva M. Lenz, (unknown), Michele Mayo, Jennifer H. Pink, Graeme R. Robb, James S. Scott, S.P. Stokes, Yafeng Xue	15
4	The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1 2017 ·PLoS ONE ·Linda Sundström, (unknown), Monika Sundqvist, Andrea Ahnmark, William McCoull, Piotr Raubo, Sam D. Groombridge, Magnus Polla, Ann‐Christin Nyström, (unknown), Mats Någård, Maria Sörhede Winzell	41
5	Regioselective ortho alkylation of nitro indole, carbazole, benzothiophene and benzofuran 2015 ·Tetrahedron Letters ·Scott G. Lamont, Craig S. Donald, (unknown), Sam D. Groombridge	0
6	Synthesis of novel, functionalised tricycles utilising the interrupted Pummerer reaction 2015 ·Tetrahedron Letters ·Scott Boyd, Robert D. M. Davies, Sébastien L. Degorce, Sam D. Groombridge, James S. Scott, S.P. Stokes	8
7	Discovery of a series of 2-(pyridinyl)pyrimidines as potent antagonists of GPR40 2015 ·MedChemComm ·Michael J. Waring, David Baker, (unknown), Alexander G. Dossetter, (unknown), (unknown), (unknown), Sam D. Groombridge, (unknown), Philip A. MacFaul, (unknown), David Morgan, (unknown), (unknown), Graeme R. Robb, David M. Smith, S.P. Stokes, Gary Wilkinson	11
8	Optimization of Brain Penetrant 11β-Hydroxysteroid Dehydrogenase Type I Inhibitors and in Vivo Testing in Diet-Induced Obese Mice 2014 ·Journal of Medicinal Chemistry ·Frederick W. Goldberg, Alexander G. Dossetter, James S. Scott, Graeme R. Robb, Scott Boyd, Sam D. Groombridge, Paul D. Kemmitt, Tove Sjögren, Pablo Morentin Gutierrez, (unknown), John G. Swales, Andrew V. Turnbull, Martin Wild	19
9	Conformational restriction in a series of GPR119 agonists: Differences in pharmacology between mouse and human 2013 ·Bioorganic & Medicinal Chemistry Letters ·James S. Scott, Katy J. Brocklehurst, Hayley S. Brown, David S. Clarke, Helen Coe, Sam D. Groombridge, (unknown), Philip A. MacFaul, Darren McKerrecher, Paul N. Schofield	14
10	Optimisation of pharmacokinetic properties in a neutral series of 11β-HSD1 inhibitors 2012 ·Bioorganic & Medicinal Chemistry Letters ·James S. Scott, Adrian L. Gill, (unknown), Sam D. Groombridge, Amanda Rees, (unknown), Paul N. Schofield, Pernilla Sörme, (unknown), John G. Swales, Paul R. O. Whittamore	11
11	Discovery and optimization of efficacious neutral 4-amino-6-biphenyl-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one diacylglycerol acyl transferase-1 (DGAT1) inhibitors 2012 ·MedChemComm ·Frederick W. Goldberg, Alan M. Birch, Andrew G. Leach, Sam D. Groombridge, (unknown), Pablo Morentin Gutierrez, (unknown), Susan Birtles, Linda K. Buckett	2
12	Rationally Designing Safer Anilines: The Challenging Case of 4-Aminobiphenyls 2012 ·Journal of Medicinal Chemistry ·Alan M. Birch, Sam D. Groombridge, Robert V. Law, Andrew G. Leach, (unknown), (unknown)	43
13	Optimisation of aqueous solubility in a series of G protein coupled receptor 119 (GPR119) agonists 2012 ·MedChemComm ·James S. Scott, Alan M. Birch, Katy J. Brocklehurst, Hayley S. Brown, Kristin Goldberg, Sam D. Groombridge, Julian A. Hudson, Andrew G. Leach, Philip A. MacFaul, Darren McKerrecher, (unknown), Paul N. Schofield, Per H. Svensson	12
14	Oxadiazole isomers: all bioisosteres are not created equal 2012 ·MedChemComm ·Kristin Goldberg, Sam D. Groombridge, Julian A. Hudson, Andrew G. Leach, Philip A. MacFaul, (unknown), (unknown), James S. Scott, Per H. Svensson, J. B. Sweeney	29
15	Free-Wilson and Structural Approaches to Co-optimizing Human and Rodent Isoform Potency for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitors 2012 ·Journal of Medicinal Chemistry ·Frederick W. Goldberg, Andrew G. Leach, James S. Scott, (unknown), Sam D. Groombridge, Craig S. Donald, (unknown), (unknown), Pablo Morentin Gutierrez, (unknown)	29
16	Property based optimisation of glucokinase activators – discovery of the phase IIb clinical candidate AZD1656 2012 ·MedChemComm ·Michael J. Waring, David S. Clarke, (unknown), (unknown), Sam D. Groombridge, Craig Johnstone, Darren McKerrecher, Kurt G. Pike, (unknown), Graeme R. Robb, (unknown)	24
17	Discovery, optimisation and in vivo evaluation of novel GPR119 agonists 2011 ·Bioorganic & Medicinal Chemistry Letters ·Katy J. Brocklehurst, Anders Broo, Roger J. Butlin, Hayley S. Brown, David S. Clarke, Öjvind Davidsson, Kristin Goldberg, Sam D. Groombridge, (unknown), Andrew G. Leach, Darren McKerrecher, Colm P. O’Donnell, Simon M. Poucher, Paul N. Schofield, James S. Scott, (unknown), (unknown), (unknown)	11

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