Saifei Lei

768 total citations
22 papers, 535 citations indexed

About

Saifei Lei is a scholar working on Molecular Biology, Pharmacology and Obstetrics and Gynecology. According to data from OpenAlex, Saifei Lei has authored 22 papers receiving a total of 535 indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 6 papers in Pharmacology and 5 papers in Obstetrics and Gynecology. Recurrent topics in Saifei Lei's work include Receptor Mechanisms and Signaling (7 papers), Pharmacogenetics and Drug Metabolism (6 papers) and Pregnancy and preeclampsia studies (4 papers). Saifei Lei is often cited by papers focused on Receptor Mechanisms and Signaling (7 papers), Pharmacogenetics and Drug Metabolism (6 papers) and Pregnancy and preeclampsia studies (4 papers). Saifei Lei collaborates with scholars based in United States, China and Australia. Saifei Lei's co-authors include Peishen Zhao, Lachlan Clydesdale, Patrick M. Sexton, Denise Wootten, Arthur Christopoulos, Cassandra Koole, Radostin Danev, Sebastian G. B. Furness, Mazdak Radjainia and Laurence J. Miller and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Saifei Lei

21 papers receiving 533 citations

Peers

Saifei Lei
Russell Desnoyer United States
Christopher K. Arnatt United States
Brooke M. Katzman United States
Debra L. Ondeyka United States
Fritz Huber Germany
Marika Manolopoulou United States
Paul L. Barclay United Kingdom
Russell Desnoyer United States
Saifei Lei
Citations per year, relative to Saifei Lei Saifei Lei (= 1×) peers Russell Desnoyer

Countries citing papers authored by Saifei Lei

Since Specialization
Citations

This map shows the geographic impact of Saifei Lei's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Saifei Lei with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Saifei Lei more than expected).

Fields of papers citing papers by Saifei Lei

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Saifei Lei. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Saifei Lei. The network helps show where Saifei Lei may publish in the future.

Co-authorship network of co-authors of Saifei Lei

This figure shows the co-authorship network connecting the top 25 collaborators of Saifei Lei. A scholar is included among the top collaborators of Saifei Lei based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Saifei Lei. Saifei Lei is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Du, Ting, Saifei Lei, Zhou Jiang, et al.. (2025). EHDPP impairs intestinal microbiota homeostasis and induces placental injury through choline mediated gut-placenta axis. Journal of Hazardous Materials. 489. 137573–137573. 2 indexed citations
2.
Zhu, Junjie, Fu‐Ying Qin, Saifei Lei, et al.. (2024). Inhibition of ABCG2 prevents phototoxicity in a mouse model of erythropoietic protoporphyria. Nature Communications. 15(1). 10557–10557. 1 indexed citations
3.
Lei, Saifei, Qian Meng, Yan‐Yun Liu, et al.. (2024). Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in β-arrestin 1/2 signaling. European Journal of Pharmacology. 968. 176419–176419. 1 indexed citations
4.
Lei, Saifei, Jie Lu, Zahir Hussain, et al.. (2023). Identification of PXR Activators from Uncaria Rhynchophylla (Gou Teng) and Uncaria Tomentosa (Cat’s Claw). Drug Metabolism and Disposition. 51(5). 629–636. 3 indexed citations
5.
Zhang, Yue, Jie Liang, Ting Du, et al.. (2023). Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction. Ecotoxicology and Environmental Safety. 266. 115605–115605. 6 indexed citations
6.
Lei, Saifei, et al.. (2023). Activation of PXR causes drug interactions with Paxlovid in transgenic mice. Acta Pharmaceutica Sinica B. 13(11). 4502–4510. 5 indexed citations
7.
Zhu, Junjie, Saifei Lei, Jie Lu, et al.. (2023). Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors. European Journal of Medicinal Chemistry. 259. 115666–115666. 9 indexed citations
8.
Lei, Saifei, Junjie Zhu, Jie Lu, et al.. (2022). Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice). Liver Research. 6(4). 251–257. 1 indexed citations
9.
Hu, Zhengyu, Yan Li, Bingwei Ma, Saifei Lei, & Xingchun Wang. (2022). Iron metabolism mediates the relationship between Vitamin C and hepatic steatosis and fibrosis in NAFLD. Frontiers in Nutrition. 9. 952056–952056. 7 indexed citations
10.
Lei, Saifei, et al.. (2021). Clinical perspectives of isoniazid-induced liver injury. Liver Research. 5(2). 45–52. 21 indexed citations
11.
Sutkevičiu̅tė, Ieva, Ji Young Lee, Alex D. White, et al.. (2021). Precise druggability of the PTH type 1 receptor. Nature Chemical Biology. 18(3). 272–280. 21 indexed citations
12.
Lei, Saifei, Gang Chen, Zhenyao Huang, et al.. (2021). LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3. Environmental Pollution. 293. 118542–118542. 14 indexed citations
13.
Li, Jianhua, Zahir Hussain, Junjie Zhu, et al.. (2021). Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity. Chemical Research in Toxicology. 34(12). 2534–2539. 5 indexed citations
14.
White, Alex D., Karina A. Peña, Lisa J. Clark, et al.. (2021). Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation. Science Signaling. 14(703). eabc5944–eabc5944. 53 indexed citations
15.
Clark, Lisa J., James Krieger, Alex D. White, et al.. (2020). Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation. Nature Chemical Biology. 16(10). 1096–1104. 39 indexed citations
16.
Lei, Saifei, Lachlan Clydesdale, Antao Dai, et al.. (2018). Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism. Journal of Biological Chemistry. 293(24). 9370–9387. 42 indexed citations
17.
Liang, Yi-Lynn, Maryam Khoshouei, Alisa Glukhova, et al.. (2018). Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex. Nature. 555(7694). 121–125. 234 indexed citations
18.
Lei, Saifei, Dehua Yang, & Ming‐Wei Wang. (2016). A historic study that opened a new chapter in nutritional science. Acta Pharmacologica Sinica. 37(12). 1641–1644.
19.
Zhou, Caihong, Yi Chen, Yanyan Shen, et al.. (2016). G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells. Oncotarget. 7(11). 12823–12839. 25 indexed citations
20.
Xiao, Ting, et al.. (2015). Application of chemical biology in target identification and drug discovery. Archives of Pharmacal Research. 38(9). 1642–1650. 11 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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