S. Wayne Mascarella

3.3k citations

98 papers · 2.7k indexed · 1 hit paper · h-index 25

Impact in

Cellular and Molecular Neuroscience top 1%
- Neuropeptides and Animal Physiology
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
Toxicology top 0.5%
- Forensic Toxicology and Drug Analysis

Papers in

Cellular and Molecular Neuroscience 48
- Neuropeptides and Animal Physiology 32
- Neurotransmitter Receptor Influence on Behavior 9
- Neuroscience and Neuropharmacology Research 7
Toxicology 6

Co-authors: F. Ivy Carroll Hernán A. Navarro Anita H. Lewin James B. Thomas Eyal Vardy Bryan L. Roth Raymond C. Stevens Richard B. Westkaemper
Journals: Journal of Medicinal Chemistry (44 papers)Tetrahedron Letters (6 papers)Bioorganic & Medicinal Chemistry Letters (5 papers)ACS Chemical Neuroscience (5 papers)Bioorganic & Medicinal Chemistry (4 papers)
Partner nations: United States United Kingdom

In The Last Decade

S. Wayne Mascarella

97 papers receiving 2.6k citations

Hit Papers

align trajectories log scale

Structure of the human κ-opioid receptor in complex with JDTic 2012 · 718 citations

Peers

Countries citing papers authored by S. Wayne Mascarella

Since Specialization

Citations

This map shows the geographic impact of S. Wayne Mascarella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by S. Wayne Mascarella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites S. Wayne Mascarella more than expected).

Fields of papers citing papers by S. Wayne Mascarella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by S. Wayne Mascarella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by S. Wayne Mascarella. The network helps show where S. Wayne Mascarella may publish in the future.

Co-authorship network

The 25 scholars most cited alongside S. Wayne Mascarella, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with S. Wayne Mascarella Line = papers co-authored together S. Wayne Mascarella links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Isolation of Hemiketal and Hydroxy Ketone Tautomers of Synthetic Intermediates Each Affording 18-Hydroxycortisol-1,6,7-d₃ ACS Omega ·Anita H. Lewin, Lourene E. Bundas, Li, Dehui� Zhang, Chad M. Kormos, S. Wayne Mascarella, Herbert H. Seltzman	2023	1
2	Designer drugs: a medicinal chemistry perspective (II) Annals of the New York Academy of Sciences ·F. Ivy Carroll, Anita H. Lewin, S. Wayne Mascarella, Herbert H. Seltzman, P. Anantha Reddy	2020	6
3	Synthesis of [³H] and [¹⁴C]genipin Journal of Labelled Compounds and Radiopharmaceuticals ·徳人三浦, David Hesk, David M. Lindsay, William J. Kerr, Bagnéris, Timothy R. Fennell, S. Wayne Mascarella, Li, Scott P. Runyon	2020	2
4	Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)-N-[1R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic) Journal of Medicinal Chemistry ·Chad M. Kormos, Pauline W. Ondachi, Scott P. Runyon, James B. Thomas, S. Wayne Mascarella, Ann M. Decker, Hernán A. Navarro, Timothy R. Fennell, Rodney W. Snyder, F. Ivy Carroll	2018	4
5	Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)-7-Hydroxy-N-[(1S)-2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (PDTic) Journal of Medicinal Chemistry ·Pauline W. Ondachi, Chad M. Kormos, Scott P. Runyon, James B. Thomas, S. Wayne Mascarella, Ann M. Decker, Hernán A. Navarro, Timothy R. Fennell, Rodney W. Snyder, F. Ivy Carroll	2018	8
6	Synthesis and physicochemical characterization of (6S)-5-formiminotetrahydrofolate; a reference standard for metabolomics Organic & Biomolecular Chemistry ·Anita H. Lewin, 都築文太, Li, Ms Mansi Zanjal, S. Wayne Mascarella, Herbert H. Seltzman	2018	1
7	Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor Antagonists ACS Medicinal Chemistry Letters ·Chad M. Kormos, Pauline W. Ondachi, Scott P. Runyon, James B. Thomas, S. Wayne Mascarella, Ann M. Decker, Hernán A. Navarro, F. Ivy Carroll	2017	9
8	Caged Naloxone: Synthesis, Characterization, and Stability of 3-O-(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX) ACS Chemical Neuroscience ·Anita H. Lewin, Interlando S., Li, Louise D. Mayer, Jason P. Burgess, S. Wayne Mascarella, P. Anantha Reddy, Herbert H. Seltzman, F. Ivy Carroll	2017	3
9	Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteres Bioorganic & Medicinal Chemistry ·Chad M. Kormos, H S Chen, Scott P. Runyon, James B. Thomas, S. Wayne Mascarella, Ann M. Decker, Hernán A. Navarro, F. Ivy Carroll	2016	4
10	Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor Molecular Pharmacology ·T. Rice, S. Wayne Mascarella, Penélope Melo, Vsevolod V. Gurevich, Hernán A. Navarro, F. Ivy Carroll, Michael R. Bruchas	2015	30
11	Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituents Bioorganic & Medicinal Chemistry ·F. Ivy Carroll, H S Chen, Chad M. Kormos, Rangan Maitra, Scott P. Runyon, James B. Thomas, S. Wayne Mascarella, Ann M. Decker, Hernán A. Navarro	2015	14
12	Emergence and properties of spice and bath salts: A medicinal chemistry perspective Life Sciences ·Anita H. Lewin, Herbert H. Seltzman, F. Ivy Carroll, S. Wayne Mascarella, P. Anantha Reddy	2013	61
13	Hydrolytic instability of the important orexin 1 receptor antagonist SB-334867: Possible confounding effects on in vivo and in vitro studies Bioorganic & Medicinal Chemistry Letters ·Donna McAlister-Kizzier, Anita H. Lewin, S. Wayne Mascarella, Scott P. Runyon, Lawrence E. Brieaddy, F. Ivy Carroll	2012	47
14	4-[(8-Alkyl-8-azabicyclo[3.2.1]octyl-3-yl)-3-arylanilino]-N,N-diethylbenzamides: high affinity, selective ligands for the delta opioid receptor illustrate factors important to antagonist activity Bioorganic & Medicinal Chemistry Letters ·James B. Thomas, Robert N. Atkinson, RB Rothman, Jason P. Burgess, S. Wayne Mascarella, John R. Werren, H. Eric Xu, F. Ivy Carroll	2000	7
15	Optically pure (−)-4-[(N-allyl-3-methyl-4-piperidinyl)phenyl-amino]-N,N-diethylbenzamide displays selective binding and full agonist activity for the δ opioid receptor Bioorganic & Medicinal Chemistry Letters ·James B. Thomas, Robert N. Atkinson, Soares José Francisco, Richard B. Rothman, S. Wayne Mascarella, Christina M. Dersch, Heng Xu, Yuen Ting Kitty Tang, F. Ivy Carroll	1999	6
16	N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines are opioid receptor pure antagonists Bioorganic & Medicinal Chemistry Letters ·James B. Thomas, S. Wayne Mascarella, Jason P. Burgess, Heng Xu, Joseph Emerson Raja, Zezhong Sun, J.L. Flippen-Anderson, Clifford George, Buddy E. Cantrell, Dennis M. Zimmerman, F. Ivy Carroll	1998	5
17	Stimulation of rat striatal tyrosine hydroxylase activity following intranigral administration of σ receptor ligands European Journal of Pharmacology ·Sheri D. Weiser, Saundra L. Patrick, S. Wayne Mascarella, Shaheen Aslam, Sarah Swerey, F. Ivy Carroll, James M. Walker, Robert L. Patrick	1995	29
18	Synthesis and Ligand Binding Study of 3.beta.-(4'-Substituted phenyl)-2.beta.-(heterocyclic)tropanes Journal of Medicinal Chemistry ·Pravin L. Kotian, Dick Chiu, Anita H. Lewin, S. Wayne Mascarella, John W. Boja, Michael J. Kuhar, F.I. Carroll	1995	20
19	(+)-cis-N-(para-, meta-, and ortho-substituted benzyl)-N-normetazocines: Synthesis and binding affinity at the [3H]-(+)-pentazocine-labeled (.sigma.1) site and quantitative structure-affinity relationship studies Journal of Medicinal Chemistry ·S. Wayne Mascarella, Xu Bai, Wanda C. Williams, Yu. E. Andrianova, Wayne D. Bowen, F. Ivy Carroll	1995	15
20	Crystal, solution, and molecular modeling structural properties and muscarinic antagonist activity of azaprophen Journal of Medicinal Chemistry ·F. Ivy Carroll, Dick Chiu, S. Wayne Mascarella, Pankaj Kumar Singh, Yaoyao Feng, John Wade, Yong Wha Kwon, David J. Triggle	1991	9

About S. Wayne Mascarella

S. Wayne Mascarella is a scholar working on Cellular and Molecular Neuroscience, Toxicology, Organic Chemistry, Molecular Biology and Pharmacology, having authored 98 papers that have together received 2.7k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (42 papers), Neuropeptides and Animal Physiology (32 papers), Pharmacological Receptor Mechanisms and Effects (30 papers), Chemical Synthesis and Analysis (15 papers), Nicotinic Acetylcholine Receptors Study (13 papers), Asymmetric Synthesis and Catalysis (11 papers), Neurotransmitter Receptor Influence on Behavior (9 papers) and Neuroscience and Neuropharmacology Research (7 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.4k citations), Toxicology (239 citations), Molecular Biology (1.8k citations), Organic Chemistry (626 citations) and Pharmacology (287 citations). S. Wayne Mascarella has collaborated with scholars based in United States and United Kingdom. Frequent co-authors include F. Ivy Carroll, F. Ivy Carroll, Hernán A. Navarro, Anita H. Lewin, James B. Thomas, Eyal Vardy, Bryan L. Roth, Raymond C. Stevens, Richard B. Westkaemper and Aaron A. Thompson. Their work appears in journals such as Journal of Medicinal Chemistry, Tetrahedron Letters, Bioorganic & Medicinal Chemistry Letters, ACS Chemical Neuroscience and Bioorganic & Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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