Ryan Fleming

2.0k citations

43 papers · 1.3k indexed · h-index 17

Impact in

Radiology, Nuclear Medicine and Imaging top 2%
- Monoclonal and Polyclonal Antibodies Research
Oncology top 5%
- HER2/EGFR in Cancer Research
- CAR-T cell therapy research
- Peptidase Inhibition and Analysis

Papers in ⓘ

Radiology, Nuclear Medicine and Imaging 17
- Monoclonal and Polyclonal Antibodies Research 17
Oncology 16
- HER2/EGFR in Cancer Research 13

Co-authors: Changshou Gao (20 shared papers)Nazzareno Dimasi (20 shared papers)Herren Wu (18 shared papers)Binyam Bezabeh (12 shared papers)Steven Coats (3 shared papers)Shenlan Mao (6 shared papers)Leslie Wetzel (4 shared papers)R. James Christie (4 shared papers)
Journals: Cancer Research (5 papers)mAbs (4 papers)Molecular Pharmaceutics (2 papers)Applied Physics Letters (2 papers)Science Translational Medicine (2 papers)
Partner nations: United States Germany South Korea

In The Last Decade

Ryan Fleming

39 papers receiving 1.2k citations

Peers

Countries citing papers authored by Ryan Fleming

Since Specialization

Citations

This map shows the geographic impact of Ryan Fleming's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ryan Fleming with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ryan Fleming more than expected).

Fields of papers citing papers by Ryan Fleming

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ryan Fleming. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ryan Fleming. The network helps show where Ryan Fleming may publish in the future.

Co-authors

The 25 scholars most cited alongside Ryan Fleming, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ryan Fleming Line = papers co-authored together Ryan Fleming links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 43 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy Cancer Cell ·John Y. Li, Samuel R. Perry, Vanessa Muniz‐Medina, Xinzhong Wang, Leslie Wetzel, Marlon C. Rebelatto, Mary Jane Hinrichs, Binyam Bezabeh, Ryan Fleming, Nazzareno Dimasi, Hui Feng, Dorin Toader, Andy Q. Yuan, Lan Xu, Jia Lin, Changshou Gao, Herren Wu, Rakesh Dixit, Jane Osbourn, Steven Coats	2016	292
2	A multifunctional bispecific antibody protects against Pseudomonas aeruginosa Science Translational Medicine ·Antonio DiGiandomenico, Ashley Keller, Cuihua Gao, G. Jonah Rainey, Paul Warrener, Mareia M. Camara, Jessica Bonnell, Ryan Fleming, Binyam Bezabeh, Nazzareno Dimasi, Bret R. Sellman, Jamese J. Hilliard, Caitlin M. Guenther, Vivekananda Datta, Zhao Wei, Changshou Gao, Xiang‐Qing Yu, JoAnn Suzich, C. Kendall Stover	2014	215
3	A Human Antibody–Drug Conjugate Targeting EphA2 Inhibits Tumor GrowthIn vivo Cancer Research ·Dowdy Jackson, John Gooya, Shenlan Mao, Krista Kinneer, Linda Xu, Margarita Camara, Christine Fazenbaker, Ryan Fleming, Sudha Swamynathan, Damon L. Meyer, Peter D. Senter, Changshou Gao, Herren Wu, Michael S. Kinch, Steven Coats, Peter A. Kiener, David A. Tice	2008	121
4	Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides Journal of Controlled Release ·R. James Christie, Ryan Fleming, Binyam Bezabeh, Rob Woods, Shenlan Mao, Jay Harper, Augustine R. Joseph, Qianli Wang, Ze‐Qi Xu, Herren Wu, Changshou Gao, Nazzareno Dimasi	2015	102
5	Antibody–Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies Cancer Research ·Jonathan Rios‐Doria, Jay Harper, Raymond Rothstein, Leslie Wetzel, Jon Chesebrough, Allison M. Marrero, Cui Chen, Patrick Strout, Kathy Mulgrew, Kelly McGlinchey, Ryan Fleming, Binyam Bezabeh, John Meekin, David J. Stewart, Maureen Kennedy, Philip Martin, Andrew Buchanan, Nazzareno Dimasi, Emil F. Michelotti, Robert E. Hollingsworth	2017	91
6	The Design and Characterization of Oligospecific Antibodies for Simultaneous Targeting of Multiple Disease Mediators Journal of Molecular Biology ·Nazzareno Dimasi, Changshou Gao, Ryan Fleming, Robert M. Woods, Xiao-Tao Yao, Lena Shirinian, Peter A. Kiener, Herren Wu	2009	75
7	Efficient Preparation of Site-Specific Antibody–Drug Conjugates Using Cysteine Insertion Molecular Pharmaceutics ·Nazzareno Dimasi, Ryan Fleming, Haihong Zhong, Binyam Bezabeh, Krista Kinneer, R. James Christie, Christine Fazenbaker, Herren Wu, Changshou Gao	2017	59
8	Mitigation of reversible self-association and viscosity in a human IgG1 monoclonal antibody by rational, structure-guided Fv engineering mAbs ·James C. Geoghegan, Ryan Fleming, Melissa Damschroder, Steven M. Bishop, Hasige A. Sathish, Reza Esfandiary	2016	55
9	A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments Biomacromolecules ·Stelios Florinas, Marc Liu, Ryan Fleming, Lilian van Vlerken-Ysla, Joanne Ayriss, Ryan Gilbreth, Nazzareno Dimasi, Changshou Gao, Herren Wu, Ze-Qi Xu, Shaoyi Chen, Anjaneyulu Dirisala, Kazunori Kataoka, Horacio Cabral, R. James Christie	2016	41
10	CD19 and CD32b Differentially Regulate Human B Cell Responsiveness The Journal of Immunology ·Jodi L. Karnell, Nazzareno Dimasi, Fredrick G. Karnell, Ryan Fleming, Ellen Kuta, Mildred Wilson, Herren Wu, Changshou Gao, Ronald Herbst, Rachel Ettinger	2014	35
11	Straightforward Glycoengineering Approach to Site-Specific Antibody–Pyrrolobenzodiazepine Conjugates ACS Medicinal Chemistry Letters ·Pamela Thompson, Ebele Ezeadi, Ian Hutchinson, Ryan Fleming, Binyam Bezabeh, Jia Lin, Shenlan Mao, Cui Chen, Luke A. Masterson, Haihong Zhong, Dorin Toader, Philip W. Howard, Herren Wu, Changshou Gao, Nazzareno Dimasi	2016	28
12	Hydrolytically Stable Site-Specific Conjugation at the N-Terminus of an Engineered Antibody Bioconjugate Chemistry ·Pamela Thompson, Binyam Bezabeh, Ryan Fleming, Monica Pruitt, Shenlan Mao, Patrick Strout, Cui Chen, Song Cho, Haihong Zhong, Herren Wu, Changshou Gao, Nazzareno Dimasi	2015	24
13	Molecular engineering strategies and methods for the expression and purification of IgG1-based bispecific bivalent antibodies Methods ·Nazzareno Dimasi, Ryan Fleming, Herren Wu, Changshou Gao	2018	18
14	Design and characterization of homogenous antibody-drug conjugates with a drug-to-antibody ratio of one prepared using an engineered antibody and a dual-maleimide pyrrolobenzodiazepine dimer mAbs ·Jason B. White, Ryan Fleming, Luke A. Masterson, Ben T. Ruddle, Haihong Zhong, Christine Fazenbaker, Patrick Strout, Kim Rosenthal, Molly Reed, Vanessa Muniz‐Medina, Philip W. Howard, Rakesh Dixit, Herren Wu, Mary Jane Hinrichs, Changshou Gao, Nazzareno Dimasi	2019	17
15	Development of a Trispecific Antibody Designed to Simultaneously and Efficiently Target Three Different Antigens on Tumor Cells Molecular Pharmaceutics ·Nazzareno Dimasi, Ryan Fleming, Carl Hay, Rob Woods, Linda Xu, Herren Wu, Changshou Gao	2015	17
16	Pyrrolobenzodiazepine Antibody-Drug Conjugates Designed for Stable Thiol Conjugation Antibodies ·R. James Christie, Arnaud Tiberghien, Qun Du, Binyam Bezabeh, Ryan Fleming, Amanda Shannon, Shenlan Mao, Shannon Breen, Jing Zhang, Haihong Zhong, Jay Harper, Herren Wu, Philip W. Howard, Changshou Gao	2017	17
17	Insertion of scFv into the hinge domain of full-length IgG1 monoclonal antibody results in tetravalent bispecific molecule with robust properties mAbs ·Binyam Bezabeh, Ryan Fleming, Christine Fazenbaker, Haihong Zhong, Karen Coffman, Xiang‐Qing Yu, Ching Ching Leow, Nerea Gibson, Susan Wilson, C. Kendall Stover, Herren Wu, Changshou Gao, Nazzareno Dimasi	2016	16
18	Characterization of Disulfide Bond Rebridged Fab–Drug Conjugates Prepared Using a Dual Maleimide Pyrrolobenzodiazepine Cytotoxic Payload ChemMedChem ·Ben T. Ruddle, Ryan Fleming, Herren Wu, Changshou Gao, Nazzareno Dimasi	2019	16
19	Abstract 5736: AZD9592: An EGFR-cMET bispecific antibody-drug conjugate (ADC) targeting key oncogenic drivers in non-small-cell lung cancer (NSCLC) and beyond Cancer Research ·Frank I. Comer, Yariv Mazor, Elaine M. Hurt, Chunning Yang, Ryan Fleming, Harini Shandilya, Balakumar Vijayakrishnan, Meghan Sterba, Ruoyan Chen, Edward Rosfjord, Nicolas Floc’h, Anton I. Rosenbaum, Yue Huang, Jiaqi Yuan, Kevin Beaumont, Lisa Godfrey, Lara McGrath, Fernanda I. Arnaldez, Puja Sapra	2023	16
20	The infrared absorption spectrum of the isolated UF5 molecule in the 580–630 cm−1 region Chemical Physics Letters ·K.C. Kim, Ryan Fleming, Daniel Seitz	1979	9

About Ryan Fleming

Ryan Fleming is a scholar working on Radiology, Nuclear Medicine and Imaging, Oncology, Molecular Biology, Electrical and Electronic Engineering and Atomic and Molecular Physics, and Optics, having authored 43 papers that have together received 1.3k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (17 papers), HER2/EGFR in Cancer Research (13 papers), Particle accelerators and beam dynamics (6 papers), Glycosylation and Glycoproteins Research (6 papers), Gyrotron and Vacuum Electronics Research (5 papers), Particle Accelerators and Free-Electron Lasers (4 papers), Diamond and Carbon-based Materials Research (4 papers) and Immune Cell Function and Interaction (3 papers). The work is most often cited by research in Radiology, Nuclear Medicine and Imaging (747 citations), Oncology (626 citations), Molecular Medicine (81 citations), Molecular Biology (606 citations) and Immunology (163 citations). Ryan Fleming has collaborated with scholars based in United States, Germany and South Korea. Frequent co-authors include Changshou Gao, Nazzareno Dimasi, Herren Wu, Binyam Bezabeh, Steven Coats, Shenlan Mao, Leslie Wetzel, R. James Christie, Dorin Toader and Peter A. Kiener. Their work appears in journals such as Cancer Research, mAbs, Molecular Pharmaceutics, Applied Physics Letters and Science Translational Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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