Nicolas Floc’h

1.7k total citations · 1 hit paper
30 papers, 1.2k citations indexed

About

Nicolas Floc’h is a scholar working on Pulmonary and Respiratory Medicine, Oncology and Molecular Biology. According to data from OpenAlex, Nicolas Floc’h has authored 30 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Pulmonary and Respiratory Medicine, 18 papers in Oncology and 12 papers in Molecular Biology. Recurrent topics in Nicolas Floc’h's work include Lung Cancer Treatments and Mutations (17 papers), HER2/EGFR in Cancer Research (7 papers) and Colorectal Cancer Treatments and Studies (4 papers). Nicolas Floc’h is often cited by papers focused on Lung Cancer Treatments and Mutations (17 papers), HER2/EGFR in Cancer Research (7 papers) and Colorectal Cancer Treatments and Studies (4 papers). Nicolas Floc’h collaborates with scholars based in United Kingdom, United States and France. Nicolas Floc’h's co-authors include Paul D. Smith, Darren McKerrecher, Richard A. Ward, Vikki Flemington, Stephen E. Fawell, Cory Abate‐Shen, Michael M. Shen, Andrea Califano, Antonina Mitrofanova and Matthew J. Martin and has published in prestigious journals such as Chemical Reviews, Journal of Clinical Oncology and PLoS ONE.

In The Last Decade

Nicolas Floc’h

29 papers receiving 1.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Challenges and Opportunities in Cancer Drug Resistance

2020 330 citations Richard A. Ward, Nicolas Floc’h et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Nicolas Floc’h United Kingdom	14	587	493	464	223	102	30	1.2k
Daniele Cretella Italy	23	466 0.8×	574 1.2×	714 1.5×	181 0.8×	105 1.0×	26	1.1k
Dhivya R. Sudhan United States	13	639 1.1×	341 0.7×	505 1.1×	416 1.9×	90 0.9×	28	1.2k
Sebastian Oeck Germany	17	907 1.5×	248 0.5×	379 0.8×	322 1.4×	129 1.3×	30	1.3k
Justine Y. Bruce United States	16	413 0.7×	275 0.6×	329 0.7×	175 0.8×	107 1.0×	73	955
Jian H. Song United States	20	977 1.7×	221 0.4×	387 0.8×	356 1.6×	101 1.0×	46	1.4k
Kristy J. Gotink Netherlands	7	609 1.0×	252 0.5×	294 0.6×	237 1.1×	42 0.4×	8	975
Ina Kurth Germany	18	600 1.0×	240 0.5×	544 1.2×	400 1.8×	112 1.1×	38	1.2k
Pascale Lejeune Germany	16	876 1.5×	373 0.8×	522 1.1×	225 1.0×	149 1.5×	44	1.6k
Andrey Ugolkov United States	24	899 1.5×	188 0.4×	453 1.0×	325 1.5×	121 1.2×	44	1.5k
Ashujit Tagde United States	17	859 1.5×	218 0.4×	432 0.9×	292 1.3×	284 2.8×	23	1.2k

Countries citing papers authored by Nicolas Floc’h

Since Specialization

Citations

This map shows the geographic impact of Nicolas Floc’h's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicolas Floc’h with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicolas Floc’h more than expected).

Fields of papers citing papers by Nicolas Floc’h

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicolas Floc’h. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicolas Floc’h. The network helps show where Nicolas Floc’h may publish in the future.

Co-authorship network of co-authors of Nicolas Floc’h

This figure shows the co-authorship network connecting the top 25 collaborators of Nicolas Floc’h. A scholar is included among the top collaborators of Nicolas Floc’h based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicolas Floc’h. Nicolas Floc’h is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Grazini, Ursula, Aleksandra Markovets, Lucy Ireland, et al.. (2024). Overcoming Osimertinib Resistance with AKT Inhibition in EGFRm-Driven Non–Small Cell Lung Cancer with PIK3CA/PTEN Alterations. Clinical Cancer Research. 30(18). 4143–4154. 12 indexed citations

Rosfjord, Edward, S. Christ, Ying Zheng, et al.. (2023). P1.12-04 In Vivo Efficacy of AZD9592, an EGFR-cMET Bispecific ADC, in a Broad Panel of NSCLC Patient-Derived Xenograft Models. Journal of Thoracic Oncology. 18(11). S208–S208. 2 indexed citations

Martin, Matthew J., Nicolas Floc’h, Matthias Pfeifer, et al.. (2022). Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells. Cancer Research Communications. 2(10). 1312–1325. 6 indexed citations

Tu, Eric, Kelly McGlinchey, Jixin Wang, et al.. (2022). Anti–PD-L1 and anti-CD73 combination therapy promotes T cell response to EGFR-mutated NSCLC. JCI Insight. 7(3). 75 indexed citations

Criscione, Steven W., Matthew J. Martin, Derek B. Oien, et al.. (2022). The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells. npj Precision Oncology. 6(1). 95–95. 22 indexed citations

Floc’h, Nicolas, Sangbin Lim, Afshan Ahmed, et al.. (2020). Osimertinib, an Irreversible Next-Generation EGFR Tyrosine Kinase Inhibitor, Exerts Antitumor Activity in Various Preclinical NSCLC Models Harboring the Uncommon EGFR Mutations G719X or L861Q or S768I. Molecular Cancer Therapeutics. 19(11). 2298–2307. 38 indexed citations

Floc’h, Nicolas, Susan Ashton, Douglas Ferguson, et al.. (2019). Modeling Dose and Schedule Effects of AZD2811 Nanoparticles Targeting Aurora B Kinase for Treatment of Diffuse Large B-cell Lymphoma. Molecular Cancer Therapeutics. 18(5). 909–919. 16 indexed citations

Floc’h, Nicolas, et al.. (2019). Abstract 1330: Osimertinib, an irreversible next generation EGFR tyrosine kinase inhibitor, exerts anti-tumor activity in various preclinical NSCLC models harboring G719X mutant-EGFR. Cancer Research. 79(13_Supplement). 1330–1330. 1 indexed citations

Ward, Richard A., Ambra Bianco, Nicola Colclough, et al.. (2019). Abstract 4813: Comparative activity profiling of tyrosine kinase inhibitors (TKIs) against exon 20 insertions and the wild-type form of epidermal growth factor receptor (EGFR). Cancer Research. 79(13_Supplement). 4813–4813. 1 indexed citations

10.

Floc’h, Nicolas, Matthew J. Martin, Jonathan W. Riess, et al.. (2018). Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions. Molecular Cancer Therapeutics. 17(5). 885–896. 85 indexed citations

11.

Ménard, Ludovic, Nicolas Floc’h, Matthew J. Martin, & Darren A.E. Cross. (2018). Reactivation of Mutant-EGFR Degradation through Clathrin Inhibition Overcomes Resistance to EGFR Tyrosine Kinase Inhibitors. Cancer Research. 78(12). 3267–3279. 33 indexed citations

12.

Floc’h, Nicolas, Susan Ashton, Paula Taylor, et al.. (2017). Optimizing Therapeutic Effect of Aurora B Inhibition in Acute Myeloid Leukemia with AZD2811 Nanoparticles. Molecular Cancer Therapeutics. 16(6). 1031–1040. 29 indexed citations

13.

Zou, Min, Roxanne Toivanen, Antonina Mitrofanova, et al.. (2017). Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer. Cancer Discovery. 7(7). 736–749. 240 indexed citations

14.

Riess, Jonathan W., Nicolas Floc’h, Matthew W. Martin, et al.. (2017). Antitumor activity of osimertinib in NSCLC harboring EGFR exon 20 insertions.. Journal of Clinical Oncology. 35(15_suppl). 9030–9030. 5 indexed citations

15.

Floc’h, Nicolas, Leila Akkari, Yannick Simonin, et al.. (2013). Modulation of Oxidative Stress by Twist Oncoproteins. PLoS ONE. 8(8). e72490–e72490. 11 indexed citations

16.

Simonin, Yannick, Serena Vegna, Leila Akkari, et al.. (2013). Lymphotoxin Signaling Is Initiated by the Viral Polymerase in HCV-linked Tumorigenesis. PLoS Pathogens. 9(3). e1003234–e1003234. 21 indexed citations

17.

Floc’h, Nicolas, Carolyn Waugh Kinkade, Takashi Kobayashi, et al.. (2012). Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model. Cancer Research. 72(17). 4483–4493. 68 indexed citations

18.

Wang, Jingqiang, Takashi Kobayashi, Nicolas Floc’h, et al.. (2012). B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer. Cancer Research. 72(18). 4765–4776. 78 indexed citations

19.

Akkari, Leila, Damien Grégoire, Nicolas Floc’h, et al.. (2012). Hepatitis C viral protein NS5A induces EMT and participates in oncogenic transformation of primary hepatocyte precursors. Journal of Hepatology. 57(5). 1021–1028. 54 indexed citations

20.

Akkari, Leila, D. Haouzi, Fabien Binamé, et al.. (2010). Cell shape and TGF‐β signaling define the choice of lineage during in vitro differentiation of mouse primary hepatic precursors. Journal of Cellular Physiology. 225(1). 186–195. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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