Ruth Brenk

3.5k total citations · 1 hit paper
61 papers, 2.3k citations indexed

About

Ruth Brenk is a scholar working on Molecular Biology, Computational Theory and Mathematics and Epidemiology. According to data from OpenAlex, Ruth Brenk has authored 61 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 46 papers in Molecular Biology, 19 papers in Computational Theory and Mathematics and 11 papers in Epidemiology. Recurrent topics in Ruth Brenk's work include Computational Drug Discovery Methods (19 papers), RNA and protein synthesis mechanisms (18 papers) and Biochemical and Molecular Research (10 papers). Ruth Brenk is often cited by papers focused on Computational Drug Discovery Methods (19 papers), RNA and protein synthesis mechanisms (18 papers) and Biochemical and Molecular Research (10 papers). Ruth Brenk collaborates with scholars based in United Kingdom, Germany and Norway. Ruth Brenk's co-authors include Paul G. Wyatt, Julie A. Frearson, Ian H. Gilbert, Alessandro Schipani, Brian K. Shoichet, G. Klebe, Torsten Luksch, David A. Robinson, N. Yi Mok and Alan P. Graves and has published in prestigious journals such as PLoS ONE, Journal of Molecular Biology and Nature Chemistry.

In The Last Decade

Ruth Brenk

60 papers receiving 2.3k citations

Hit Papers

Lessons Learnt from Assembling Screening Libraries for Dr... 2007 2026 2013 2019 2007 100 200 300 400
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases
    2007 482 citations Ruth Brenk, Ian H. Gilbert et al. ChemMedChem profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Ruth Brenk United Kingdom 27 1.5k 754 659 277 262 61 2.3k
Floriano Paes Silva Brazil 24 962 0.6× 726 1.0× 505 0.8× 132 0.5× 143 0.5× 70 2.2k
Georgina A. Holloway Australia 10 1.9k 1.3× 932 1.2× 1.1k 1.6× 211 0.8× 207 0.8× 12 3.3k
Carlos A. Montanari Brazil 27 858 0.6× 746 1.0× 576 0.9× 477 1.7× 126 0.5× 128 2.1k
Bruno J. Neves Brazil 20 607 0.4× 579 0.8× 586 0.9× 202 0.7× 119 0.5× 73 1.7k
Daniel Bur Switzerland 32 1.5k 1.0× 1.0k 1.4× 462 0.7× 95 0.3× 165 0.6× 88 2.9k
Andreas Larsson Sweden 21 1.9k 1.3× 473 0.6× 312 0.5× 206 0.7× 115 0.4× 55 2.9k
Amy C. Anderson United States 30 1.9k 1.3× 649 0.9× 574 0.9× 269 1.0× 405 1.5× 84 2.9k
David Lagorce France 25 1.4k 0.9× 361 0.5× 933 1.4× 576 2.1× 152 0.6× 34 2.6k
Ashfaq Ur Rehman Pakistan 31 1.3k 0.9× 1.1k 1.5× 528 0.8× 94 0.3× 128 0.5× 122 2.9k
Dana E. Vanderwall United States 20 1.3k 0.9× 599 0.8× 367 0.6× 171 0.6× 128 0.5× 28 2.2k

Countries citing papers authored by Ruth Brenk

Since Specialization
Citations

This map shows the geographic impact of Ruth Brenk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruth Brenk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruth Brenk more than expected).

Fields of papers citing papers by Ruth Brenk

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruth Brenk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruth Brenk. The network helps show where Ruth Brenk may publish in the future.

Co-authorship network of co-authors of Ruth Brenk

This figure shows the co-authorship network connecting the top 25 collaborators of Ruth Brenk. A scholar is included among the top collaborators of Ruth Brenk based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ruth Brenk. Ruth Brenk is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Xia, Qing, et al.. (2024). Assessing small molecule conformational sampling methods in molecular docking. Journal of Computational Chemistry. 46(1). e27516–e27516. 3 indexed citations
2.
Sreeramulu, Sridhar, Christian Richter, Edgar Specker, et al.. (2024). Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection. RSC Medicinal Chemistry. 15(4). 1176–1188. 7 indexed citations
3.
Hänzelmann, Petra, Christoph Wiedemann, Ute A. Hellmich, et al.. (2022). Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97. Communications Chemistry. 5(1). 169–169. 5 indexed citations
4.
Gotfredsen, Charlotte H., et al.. (2021). Fragment‐Based Drug Discovery for RNA Targets. ChemMedChem. 16(17). 2588–2603. 24 indexed citations
5.
Kiefer, Werner, et al.. (2019). Identification of a potential allosteric site of Golgi α-mannosidase II using computer-aided drug design. PLoS ONE. 14(5). e0216132–e0216132. 6 indexed citations
6.
Harrison, Justin R., Stephen Brand, Victoria Smith, et al.. (2018). A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N -Myristoyltransferase Inhibitors. Journal of Medicinal Chemistry. 61(18). 8374–8389. 46 indexed citations
7.
Linciano, Pasquale, Giuseppe Celenza, Pierangelo Bellio, et al.. (2018). In silico identification and experimental validation of hits active against KPC-2 β-lactamase. PLoS ONE. 13(11). e0203241–e0203241. 9 indexed citations
8.
Bayliss, Tracy, David A. Robinson, Victoria Smith, et al.. (2017). Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors. Journal of Medicinal Chemistry. 60(23). 9790–9806. 16 indexed citations
9.
Sarkar, Aurijit & Ruth Brenk. (2015). To Hit or Not to Hit, That Is the Question – Genome-wide Structure-Based Druggability Predictions for Pseudomonas aeruginosa Proteins. PLoS ONE. 10(9). e0137279–e0137279. 8 indexed citations
10.
11.
Daldrop, Peter & Ruth Brenk. (2013). Structure-Based Virtual Screening for the Identification of RNA-Binding Ligands. Methods in molecular biology. 1103. 127–139. 6 indexed citations
12.
Brenk, Ruth & Daniel Rauh. (2012). Change or be changed. Bioorganic & Medicinal Chemistry. 20(12). 3695–3697. 1 indexed citations
13.
Smith, Victoria, Laura A. T. Cleghorn, Andrew Woodland, et al.. (2011). Optimisation of the Anti‐Trypanosoma brucei Activity of the Opioid Agonist U50488. ChemMedChem. 6(10). 1832–1840. 6 indexed citations
14.
Spinks, Daniel, Han B. Ong, Chidochangu P. Mpamhanga, et al.. (2010). Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1. ChemMedChem. 6(2). 302–308. 32 indexed citations
15.
Ruda, G.F., Gordon Campbell, Vincent Pius Alibu, et al.. (2010). Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase. Bioorganic & Medicinal Chemistry. 18(14). 5056–5062. 19 indexed citations
16.
Engeholm, Maik, Martijn de Jager, Andrew Flaus, et al.. (2009). Nucleosomes can invade DNA territories occupied by their neighbors. Nature Structural & Molecular Biology. 16(2). 151–158. 89 indexed citations
17.
18.
Brenk, Ruth, Stefan W. Vetter, S.E. Boyce, David B. Goodin, & Brian K. Shoichet. (2006). Probing Molecular Docking in a Charged Model Binding Site. Journal of Molecular Biology. 357(5). 1449–1470. 55 indexed citations
19.
Brenk, Ruth, John J. Irwin, & Brian K. Shoichet. (2005). Here Be Dragons: Docking and Screening in an Uncharted Region of Chemical Space. SLAS DISCOVERY. 10(7). 667–674. 34 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Floriano Paes Silva Breakdown of academic impact, for papers by Georgina A. Holloway Breakdown of academic impact, for papers by Carlos A. Montanari Breakdown of academic impact, for papers by Bruno J. Neves Breakdown of academic impact, for papers by Daniel Bur Breakdown of academic impact, for papers by Andreas Larsson Breakdown of academic impact, for papers by Amy C. Anderson Breakdown of academic impact, for papers by David Lagorce Breakdown of academic impact, for papers by Ashfaq Ur Rehman Breakdown of academic impact, for papers by Dana E. Vanderwall
Rankless by CCL
2026