Roberta Fruttero

6.0k citations

205 papers · 4.8k indexed · 1 hit paper · h-index 36

Impact in

Organic Chemistry top 1%
- Synthesis and Biological Evaluation
- Synthesis and biological activity
Biochemistry top 1%
- Eicosanoids and Hypertension Pharmacology

Papers in ⓘ

Organic Chemistry 94
- Synthesis and Biological Evaluation 31
- Free Radicals and Antioxidants 16
- Synthesis and Characterization of Heterocyclic Compounds 13
- Synthesis and biological activity 13
Biochemistry 19
- Eicosanoids and Hypertension Pharmacology 14

Co-authors: Alberto Gasco (144 shared papers)Loretta Lazzarato (63 shared papers)Barbara Rolando (67 shared papers)Antonella Di Stilo (46 shared papers)Konstantin Chegaev (42 shared papers)Clara Cena (36 shared papers)Stefano Guglielmo (32 shared papers)Giovanni Sorba (25 shared papers)
Journals: Journal of Medicinal Chemistry (27 papers)European Journal of Medicinal Chemistry (13 papers)ChemMedChem (11 papers)Bioorganic & Medicinal Chemistry (11 papers)Pharmaceutical Research (7 papers)
Partner nations: Italy Switzerland United Kingdom

In The Last Decade

Roberta Fruttero

203 papers receiving 4.7k citations

Hit Papers

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Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells 2011 · 510 citations

Peers

Countries citing papers authored by Roberta Fruttero

Since Specialization

Citations

This map shows the geographic impact of Roberta Fruttero's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberta Fruttero with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberta Fruttero more than expected).

Fields of papers citing papers by Roberta Fruttero

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberta Fruttero. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberta Fruttero. The network helps show where Roberta Fruttero may publish in the future.

Co-authors

The 25 scholars most cited alongside Roberta Fruttero, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Roberta Fruttero Line = papers co-authored together Roberta Fruttero links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 205 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells The Journal of Experimental Medicine ·Barbara Molon, Stefano Ugel, Federica Del Pozzo, Cristiana Soldani, Serena Zilio, Debora Avella, Antonella De Palma, Pierluigi Mauri, Ana Monegal, María Rescigno, Benedetta Savino, Piergiuseppe Colombo, Nives Jonjić, Sanja Pečanić, Loretta Lazzarato, Roberta Fruttero, Alberto Gasco, Vincenzo Bronte, Antonella Viola Hit paper breakdown →	2011	510
2	Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors Drug Resistance Updates ·Sabrina Dallavalle, Vladimir Dobričić, Loretta Lazzarato, Elena Gazzano, Miguel Machuqueiro, Ilza Pajeva, Ivanka Tsakovska, Nace Zidar, Roberta Fruttero	2020	235
3	Furoxans as Nitric Oxide Donors. 4-Phenyl-3-furoxancarbonitrile: Thiol-Mediated Nitric Oxide Release and Biological Evaluation Journal of Medicinal Chemistry ·Claudio Medana, Giuseppe Ermondi, Roberta Fruttero, Antonella Di Stilo, Carlo Ferretti, A. Gasco	1994	109
4	Water Soluble Furoxan Derivatives as NO Prodrugs Journal of Medicinal Chemistry ·Giovanni Sorba, Claudio Medana, Roberta Fruttero, Clara Cena, Antonella Di Stilo, Ubaldina Galli, Alberto Gasco	1997	90
5	Liposome/water lipophilicity: Methods, information content, and pharmaceutical applications Medicinal Research Reviews ·Georgette Plemper van Balen, Catherine a Marca Martinet, Giulia Caron, Géraldine Bouchard, Marianne Reist, Pierre‐Alain Carrupt, Roberta Fruttero, Alberto Gasco, Bernard Testa	2004	87
6	Antiinflammatory, Gastrosparing, and Antiplatelet Properties of New NO-Donor Esters of Aspirin Journal of Medicinal Chemistry ·Clara Cena, Marco L. Lolli, Loretta Lazzarato, Elena Guaita, Giuseppina Morini, Gabriella Coruzzi, Stuart P. McElroy, Ian L. Megson, Roberta Fruttero, Alberto Gasco	2003	86
7	Molecular Factors Influencing Retention on Immobilized Artificial Membranes (IAM) Compared to Partitioning in Liposomes and n-Octanol Pharmaceutical Research ·Agnes Taillardat-Bertschinger, Catherine a Marca Martinet, Pierre‐Alain Carrupt, Marianne Reist, Giulia Caron, Roberta Fruttero, Bernard Testa	2002	78
8	A new class of furoxan derivatives as NO donors: mechanism of action and biological activity British Journal of Pharmacology ·R. Ferioli, Giancarlo Folco, C. Ferretti, Alberto Gasco, Claudio Medana, Roberta Fruttero, Maurizio Civelli	1995	73
9	Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors Journal of Controlled Release ·Elena Gazzano, Barbara Rolando, Konstantin Chegaev, Iris C. Salaroglio, Joanna Kopecka, Isabella Pedrini, Simona Saponara, Matteo Sorge, Ilaria Buondonno, Barbara Stella, Alessandro Marengo, Massimo Valoti, Mara Brancaccio, Roberta Fruttero, Alberto Gasco, Silvia Arpicco, Chiara Riganti	2017	68
10	Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis European Journal of Medicinal Chemistry ·Guilherme Fernandes, Paula Carolina de Souza, Leonardo Biancolino Marino, Konstantin Chegaev, Stefano Guglielmo, Loretta Lazzarato, Roberta Fruttero, Chung Man Chin, Fernando R. Pavan, Jean Leandro dos Santos	2016	64
11	Mitochondrial-Targeting Nitrooxy-doxorubicin: A New Approach To Overcome Drug Resistance Molecular Pharmaceutics ·Chiara Riganti, Barbara Rolando, Joanna Kopecka, Ivana Campia, Konstantin Chegaev, Loretta Lazzarato, Antonella Federico, Roberta Fruttero, Dario Ghigo	2012	61
12	Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity ACS Medicinal Chemistry Letters ·Konstantin Chegaev, Chiara Riganti, Loretta Lazzarato, Barbara Rolando, Stefano Guglielmo, Ivana Campia, Roberta Fruttero, Amalia Bosìa, Alberto Gasco	2011	59
13	A New Class of Ibuprofen Derivatives with Reduced Gastrotoxicity Journal of Medicinal Chemistry ·Marco L. Lolli, Clara Cena, Claudio Medana, Loretta Lazzarato, Giuseppina Morini, Gabriella Coruzzi, Stefano Manarini, Roberta Fruttero, Alberto Gasco	2001	59
14	NO-Donor COX-2 Inhibitors. New Nitrooxy-Substituted 1,5-Diarylimidazoles Endowed with COX-2 Inhibitory and Vasodilator Properties Journal of Medicinal Chemistry ·Konstantin Chegaev, Loretta Lazzarato, Paolo Tosco, Clara Cena, Elisabetta Marini, Barbara Rolando, Pierre‐Alain Carrupt, Roberta Fruttero, Alberto Gasco	2007	55
15	Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts Cancer Letters ·Elena Gazzano, Ilaria Buondonno, Alessandro Marengo, Barbara Rolando, Konstantin Chegaev, Joanna Kopecka, Simona Saponara, Matteo Sorge, Claudia Maria Hattinger, Alberto Gasco, Roberta Fruttero, Mara Brancaccio, Massimo Serra, Barbara Stella, Elias Fattal, Silvia Arpicco, Chiara Riganti	2019	54
16	NO donors: Focus on furoxan derivatives Pure and Applied Chemistry ·Alberto Gasco, Roberta Fruttero, Giovanni Sorba, Antonella Di Stilo, R. CALVINO	2004	54
17	Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein Journal of Medicinal Chemistry ·Roberta Fruttero, Marco Crosetti, Konstantin Chegaev, Stefano Guglielmo, Alberto Gasco, Francesco Berardi, Mauro Niso, Roberto Perrone, Maria Antonietta Panaro, Nicola Antonio Colabufo	2010	51
18	Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma Cellular and Molecular Life Sciences ·Ilaria Buondonno, Elena Gazzano, Elisa Tavanti, Konstantin Chegaev, Joanna Kopecka, Marilù Fanelli, Barbara Rolando, Roberta Fruttero, Alberto Gasco, Claudia Maria Hattinger, Massimo Serra, Chiara Riganti	2018	50
19	Physicochemical Profiling of Sartans: A Detailed Study of Ionization Constants and Distribution Coefficients Helvetica Chimica Acta ·Paolo Tosco, Barbara Rolando, Roberta Fruttero, Yveline Henchoz, Sophie Martel, Pierre‐Alain Carrupt, Alberto Gasco	2008	50
20	Mechanism of action of novel NO‐releasing furoxan derivatives of aspirin in human platelets British Journal of Pharmacology ·Catriona M Turnbull, Clara Cena, Roberta Fruttero, Alberto Gasco, Adriano G. Rossi, Ian L. Megson	2006	49

About Roberta Fruttero

Roberta Fruttero is a scholar working on Organic Chemistry, Biochemistry, Physiology, Physical and Theoretical Chemistry and Pharmacology, having authored 205 papers that have together received 4.8k indexed citations. Recurring topics across this work include Nitric Oxide and Endothelin Effects (39 papers), Synthesis and Biological Evaluation (31 papers), Free Radicals and Antioxidants (16 papers), Drug Transport and Resistance Mechanisms (14 papers), Inflammatory mediators and NSAID effects (14 papers), Eicosanoids and Hypertension Pharmacology (14 papers), Synthesis and Characterization of Heterocyclic Compounds (13 papers) and Synthesis and biological activity (13 papers). The work is most often cited by research in Organic Chemistry (1.8k citations), Biochemistry (399 citations), Physical and Theoretical Chemistry (298 citations), Toxicology (111 citations) and Oncology (784 citations). Roberta Fruttero has collaborated with scholars based in Italy, Switzerland and United Kingdom. Frequent co-authors include Alberto Gasco, Loretta Lazzarato, Barbara Rolando, Antonella Di Stilo, Konstantin Chegaev, Clara Cena, Stefano Guglielmo, Giovanni Sorba, Elena Gazzano and Donatella Boschi. Their work appears in journals such as Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, ChemMedChem, Bioorganic & Medicinal Chemistry and Pharmaceutical Research.

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