Roberto Perrone

4.1k citations

144 papers · 3.6k indexed · h-index 36

Impact in

Cellular and Molecular Neuroscience top 2%
- Neurotransmitter Receptor Influence on Behavior
- Neuropeptides and Animal Physiology
- Neuroscience and Neuropharmacology Research
Organic Chemistry top 2%

Papers in ⓘ

Molecular Biology 104
- Pharmacological Receptor Mechanisms and Effects 54
- Receptor Mechanisms and Signaling 51
- Phenothiazines and Benzothiazines Synthesis and Activities 15
Organic Chemistry 56
- Synthesis and Biological Evaluation 18

Co-authors: Francesco Berardi (121 shared papers)Nicola Antonio Colabufo (94 shared papers)Marcello Leopoldo (64 shared papers)Enza Lacivita (42 shared papers)Mauro Niso (49 shared papers)Marialessandra Contino (46 shared papers)Vincenzo Tortorella (42 shared papers)Carmen Abate (24 shared papers)
Journals: Journal of Medicinal Chemistry (44 papers)Bioorganic & Medicinal Chemistry (14 papers)European Journal of Medicinal Chemistry (10 papers)Bioorganic & Medicinal Chemistry Letters (8 papers)ChemMedChem (8 papers)
Partner nations: Italy United States Netherlands

In The Last Decade

Roberto Perrone

141 papers receiving 3.6k citations

Peers

Countries citing papers authored by Roberto Perrone

Since Specialization

Citations

This map shows the geographic impact of Roberto Perrone's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberto Perrone with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberto Perrone more than expected).

Fields of papers citing papers by Roberto Perrone

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberto Perrone. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberto Perrone. The network helps show where Roberto Perrone may publish in the future.

Co-authors

The 25 scholars most cited alongside Roberto Perrone, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Roberto Perrone Line = papers co-authored together Roberto Perrone links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 144 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Serotonin 5-HT7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disorders Pharmacology & Therapeutics ·Marcello Leopoldo, Enza Lacivita, Francesco Berardi, Roberto Perrone, Peter B. Hedlund	2010	162
2	Antiproliferative and cytotoxic effects of some ?2 agonists and ?1 antagonists in tumour cell lines Naunyn-Schmiedeberg s Archives of Pharmacology ·NicolaAntonio Colabufo, Francesco Berardi, Marialessandra Contino, Mauro Niso, Carmen Abate, Roberto Perrone, Vincenzo Tortorella	2004	106
3	Perspectives of P-Glycoprotein Modulating Agents in Oncology and Neurodegenerative Diseases: Pharmaceutical, Biological, and Diagnostic Potentials Journal of Medicinal Chemistry ·Nicola Antonio Colabufo, Francesco Berardi, Mariangela Cantore, Marialessandra Contino, Carmela Inglese, Mauro Niso, Roberto Perrone	2009	101
4	Cyclohexylpiperazine derivative PB28, a σ2 agonist and σ1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer Molecular Cancer Therapeutics ·Amalia Azzariti, Nicola Antonio Colabufo, Francesco Berardi, Letizia Porcelli, Mauro Niso, G. Simone, Roberto Perrone, Angelo Paradiso	2006	96
5	High Affinity and Selectivity on 5-HT1A Receptor of 1-Aryl-4-[(1-tetralin)alkyl]piperazines. 2 Journal of Medicinal Chemistry ·Roberto Perrone, Francesco Berardi, Nicola Antonio Colabufo, Marcello Leopoldo, Vincenzo Tortorella, Francesco Fiorentini, V.R. Olgiati, Alberto Ghiglieri, Stefano Govoni	1995	85
6	5-HT1A Receptor, an Old Target for New Therapeutic Agents Current Topics in Medicinal Chemistry ·Enza Lacivita, Marcello Leopoldo, Francesco Berardi, Roberto Perrone	2008	76
7	Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives Bioorganic & Medicinal Chemistry ·Nicola Antonio Colabufo, Francesco Berardi, Mariangela Cantore, Maria Grazia Perrone, Marialessandra Contino, Carmela Inglese, Mauro Niso, Roberto Perrone, Amalia Azzariti, G. Simone, Letizia Porcelli, Angelo Paradiso	2007	73
8	Structure−Affinity Relationship Study on N-[4-(4-Arylpiperazin-1-yl)butyl]arylcarboxamides as Potent and Selective Dopamine D₃ Receptor Ligands Journal of Medicinal Chemistry ·Marcello Leopoldo, Francesco Berardi, Nicola Antonio Colabufo, Paola De Giorgio, Enza Lacivita, Roberto Perrone, Vincenzo Tortorella	2002	67
9	Developments in fluorescent probes for receptor research Drug Discovery Today ·Marcello Leopoldo, Enza Lacivita, Francesco Berardi, Roberto Perrone	2009	66
10	LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor Neuroscience Letters ·Peter B. Hedlund, Marcello Leopoldo, Silvio Caccia, Gor Sarkisyan, Claudia Fracasso, Giuliana Martelli, Enza Lacivita, Francesco Berardi, Roberto Perrone	2010	65
11	4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cyclohexylpiperazine as σ Receptor Ligands with Agonist σ₂ Activity Journal of Medicinal Chemistry ·Francesco Berardi, Savina Ferorelli, Carmen Abate, Nicola Antonio Colabufo, Marialessandra Contino, Roberto Perrone, Vincenzo Tortorella	2004	64
12	Structure−Affinity Relationship Study onN-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-Piperazinealkylamides, a New Class of 5-Hydroxytryptamine₇Receptor Agents Journal of Medicinal Chemistry ·Marcello Leopoldo, Francesco Berardi, Nicola Antonio Colabufo, Marialessandra Contino, Enza Lacivita, Mauro Niso, Roberto Perrone, Vincenzo Tortorella	2004	63
13	Structural Modifications of N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-piperazinehexanamides: Influence on Lipophilicity and 5-HT₇ Receptor Activity. Part III Journal of Medicinal Chemistry ·Marcello Leopoldo, Enza Lacivita, Paola De Giorgio, Claudia Fracasso, Sara Guzzetti, Silvio Caccia, Marialessandra Contino, Nicola Antonio Colabufo, Francesco Berardi, Roberto Perrone	2008	61
14	Sigma‐2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity ChemMedChem ·Mauro Niso, Carmen Abate, Marialessandra Contino, Savina Ferorelli, Amalia Azzariti, Roberto Perrone, Nicola Antonio Colabufo, Francesco Berardi	2013	57
15	ABC Pumps and Their Role in Active Drug Transport Current Topics in Medicinal Chemistry ·Nicola Antonio Colabufo, Francesco Berardi, Marialessandra Contino, Mauro Niso, Roberto Perrone	2009	54
16	Is the σ₂ Receptor a Histone Binding Protein? Journal of Medicinal Chemistry ·Nicola Antonio Colabufo, Francesco Berardi, Carmen Abate, Marialessandra Contino, Mauro Niso, Roberto Perrone	2006	54
17	4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators Bioorganic & Medicinal Chemistry ·Nicola Antonio Colabufo, Francesco Berardi, Mariangela Cantore, Maria Grazia Perrone, Marialessandra Contino, Carmela Inglese, Mauro Niso, Roberto Perrone, Amalia Azzariti, G. Simone, (unknown)	2008	51
18	Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein Journal of Medicinal Chemistry ·Roberta Fruttero, Marco Crosetti, Konstantin Chegaev, Stefano Guglielmo, Alberto Gasco, Francesco Berardi, Mauro Niso, Roberto Perrone, Maria Antonietta Panaro, Nicola Antonio Colabufo	2010	51
19	Structure−Activity Relationship Study onN-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a Class of 5-HT₇Receptor Agents. 2 Journal of Medicinal Chemistry ·Marcello Leopoldo, Enza Lacivita, Marialessandra Contino, Nicola Antonio Colabufo, Francesco Berardi, Roberto Perrone	2007	50
20	Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers Journal of Medicinal Chemistry ·Carmen Abate, Mauro Niso, Enza Lacivita, Philip D. Mosier, Annamaria Toscano, Roberto Perrone	2011	50

About Roberto Perrone

Roberto Perrone is a scholar working on Molecular Biology, Organic Chemistry, Cellular and Molecular Neuroscience, Oncology and Infectious Diseases, having authored 144 papers that have together received 3.6k indexed citations. Recurring topics across this work include Pharmacological Receptor Mechanisms and Effects (54 papers), Receptor Mechanisms and Signaling (51 papers), Drug Transport and Resistance Mechanisms (29 papers), Neurotransmitter Receptor Influence on Behavior (28 papers), Neuropeptides and Animal Physiology (20 papers), Synthesis and Biological Evaluation (18 papers), Phenothiazines and Benzothiazines Synthesis and Activities (15 papers) and HIV/AIDS drug development and treatment (13 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.1k citations), Organic Chemistry (1.0k citations), Molecular Biology (2.4k citations), Oncology (702 citations) and Biological Psychiatry (56 citations). Roberto Perrone has collaborated with scholars based in Italy, United States and Netherlands. Frequent co-authors include Francesco Berardi, Nicola Antonio Colabufo, Marcello Leopoldo, Enza Lacivita, Mauro Niso, Marialessandra Contino, Vincenzo Tortorella, Carmen Abate, Savina Ferorelli and Carmela Inglese. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, European Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters and ChemMedChem.

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